- Must visit
Royal Museums of Fine Arts of Belgium
Major museum complex with Old Masters, Magritte works, and Belgian art; one of the city’s essential cultural visits.
Cheapest price
$121
Average price
$149
Fastest journey
1 d 1 h 10 m
Average duration
1 d 3 h 8 m
Buses per day
12
Distance
1174 km
The best way to find a cheap bus ticket from Rome to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Brussels will cost around $149 if you buy it on the day, but the cheapest tickets can be found for only $121.
It's difficult to get from Rome to Brussels without transferring at least once.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
4788 · 50327
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Rome to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $86. For those with little time consider booking a flight which can get you there in 3h 7m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 2.9kg. The ticket price range depends on the travel mode: a bus costs an average of $86, and a flight costs an average of $33.
Distance: 729 miles (1174 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$134 Average price Cheapest | $164 Average price | $430 Average price (fuel + tolls) |
27h 8m Average total duration 26h 38m Onboard + 30m Additional time* | 6h 7m Average total duration Fastest 3h 7m Onboard + 3h 0m Additional time* | 15h 30m Average total duration (door-to-door) |
1.2 - 2.9kg CO2 emissions Lowest | 3.5 - 7.0kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Rome to Brussels:
A bus is $30 (€24) less than a flight for this route with tickets for a flight from Rome to Brussels costing on average $164 (€134).
Other travel options to Brussels take longer:
Train takes on average 20h 4m.
Bus takes on average 26h 38m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:20AM | Arrival Time 12:25PM | Duration 35h05 | Departure days Tue | Cheapest price $189 |
Operator FlixBus | Departure Time 07:45AM | Arrival Time 12:20PM | Duration 28h35 | Departure days Mon, Thu, Fri, Sat | Cheapest price $115 |
Operator FlixBus | Departure Time 08:50AM | Arrival Time 12:45PM | Duration 27h55 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $87 |
Operator FlixBus | Departure Time 09:30AM | Arrival Time 01:55PM | Duration 28h25 | Departure days Everyday | Cheapest price $82 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 03:45PM | Duration 29h05 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $107 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 07:35PM | Duration 31h25 | Departure days Tue, Wed, Thu, Fri, Sat | Cheapest price $102 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 03:45PM | Duration 26h40 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $102 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 10:10PM | Duration 31h25 | Departure days Sat, Sun | Cheapest price $119 |
Operator BlaBlaCar Bus | Departure Time 03:20PM | Arrival Time 05:30PM | Duration 26h10 | Departure days Wed, Thu, Sat, Sun | Cheapest price $127 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 01:10AM | Duration 29h10 | Departure days Everyday | Cheapest price $80 |
Operator FlixBus | Departure Time 09:45PM | Arrival Time 07:20AM | Duration 33h35 | Departure days Tue | Cheapest price $101 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 03:05AM | Duration 28h20 | Departure days Everyday | Cheapest price $84 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 07:20AM | Duration 32h25 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $81 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 07:20AM | Duration 31h45 | Departure days Everyday | Cheapest price $91 |
The table below shows live departures for Rome to Brussels buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 7:45 AM Roma, Autostazione Tiburtina | 28h35 | 12:20 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus | 8:50 AM Roma, Autostazione Tiburtina | 27h55 | 12:45 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 28h25 | 1:55 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 29h05 | 3:45 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 31h25 | 7:35 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 26h40 | 3:45 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 29h10 | 1:10 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:45 PM Roma, Autostazione Tiburtina | 28h20 | 3:05 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 32h25 | 7:20 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:35 PM Roma, Autostazione (Metro Anagnina) | 31h45 | 7:20 AM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Rome to Brussels run on average 10 times per day, taking around 26h 38m. Cheap bus tickets for this journey start at $86 (€70) but you can travel from only $33 (€27) by flight.
The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 729 miles (1174 km) distance in 25h 10m.
Distance 729 miles (1174 km) |
Average bus duration 26h 38m |
Cheapest ticket price $86 (€70) |
Buses per day 10 |
Fastest bus 25h 10m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Jul |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Thu |
Best time to book 49 days |
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Major museum complex with Old Masters, Magritte works, and Belgian art; one of the city’s essential cultural visits.
Dedicated to René Magritte, with the world’s largest collection of his surrealist works in a central historic setting.
Celebrated museum in an Art Nouveau building, known for its global instrument collection and audio-guided displays.
Popular cultural hill and viewpoint linking the upper and lower city, especially photogenic at sunset.
Historic covered arcade of elegant passages, shops, and architecture, often highlighted in social media imagery.
Stylish square known for antiques, refined atmosphere, and easy access to nearby churches and museums.
Brussels classic of mussels steamed with white wine, celery, onions, or cream, served with crisp fries. It is one of the city’s most iconic comfort dishes.
Traditional Belgian beef and onion stew slowly cooked with dark beer, often slightly sweet-sour and served with fries or bread. A staple in Brussels brasseries.
Rustic mashed potatoes mixed with vegetables such as carrots, leeks, or spinach, often served with sausage or meat. The base preparation is a classic local side dish.
One of Brussels’ most famous fine-dining restaurants, celebrated for refined Belgian and French cuisine in an elegant Art Nouveau setting.
Respected restaurant specializing in carefully prepared Belgian cuisine and strong beer pairings, with a cozy, polished brasserie feel.
Well-known old-school restaurant serving generous Belgian specialties such as carbonnade, stoemp, and sausage in a rustic, bustling atmosphere.
Moderate by Western European standards. Food and transport are manageable, but central hotels cost more.
Service is usually included. Rounding up or leaving 5-10% for great restaurant service is appreciated, not required. Round up taxi fares; no tip is expected for bars or cafés.
Official public transport app
Brussels South (Gare du Midi), Brussels -> Brussels Central Station, Brussels
Find answers to the most common questions about traveling from Rome to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Rome to Brussels buses use the Roma, Autostazione Tiburtina to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Brussels, Gare Du Midi. Use this guide to compare Rome and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Here are some other resources that might have the information you need