Karlovy Vary to Brno bus with FlixBus

Sat, Jun 20
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The cheapest and fastest buses from Karlovy Vary to Brno

Showing times and prices for Jun 20

Cheapest price

$16

Average price

$20

Fastest journey

4 h 50 m

Average duration

5 h 17 m

Buses per day

19

Distance

292 km

Cheap tickets

The best way to find a cheap bus ticket from Karlovy Vary to Brno is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Karlovy Vary to Brno will cost around $20 if you buy it on the day, but the cheapest tickets can be found for only $16.

Fast buses

Of the 19 buses that leave Karlovy Vary for Brno on Sat, Jun 20, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Sat, Jun 20 the direct buses cover the 292 km distance in an average of 5 h 17 m but if you time it right, some buses will get you there in just 4 h 50 m .

On Sat, Jun 20 the slowest buses will take 5 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBusFlixBus
    4:10 PM4h50
    Karlovy Vary, Dolní Nádraží
    9:00 PMBrno, Benešova - Grandhotel (Hlavní nádraží)
    $161One-way
    0 transfers
  • FlixBusFlixBus
    5:55 AM6h15
    Karlovy Vary, Dolní Nádraží
    12:10 PMBrno, Benešova - Grandhotel (Hlavní nádraží)
    $161One-way
    0 transfers
  • FlixBusFlixBus · FlixBus
    12:30 PM5h35
    Karlovy Vary, Dolní Nádraží
    6:05 PMBrno, Benešova - Grandhotel (Hlavní nádraží)
    $171One-way
    1 transfer
  • FlixBusFlixBus · FlixBus
    9:30 AM5h10
    Karlovy Vary, Dolní Nádraží
    2:40 PMBrno, Benešova - Grandhotel (Hlavní nádraží)
    $171One-way
    1 transfer
  • FlixBusFlixBus · FlixBus
    6:15 AM5h55
    Karlovy Vary, Dolní Nádraží
    12:10 PMBrno, Benešova - Grandhotel (Hlavní nádraží)
    $171One-way
    1 transfer

Travel Information

Compare bus and train for Karlovy Vary to Brno

Omio recommends booking the bus as it is the most popular option from Karlovy Vary to Brno among Omio's users. If you are prioritising price take the bus with prices starting from $8. For those with little time consider booking a bus which can get you there in 5h 2m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $8, and a train costs an average of $16.

Distance: 181 miles (292 km)

Compare bus with

Most popular
Bus
Train
Driving

$14

Average price

Cheapest

$32

Average price

$78

Average price

(fuel + tolls)

5h 32m

Average total duration

Fastest

5h 2m

Onboard

+

30m

Additional time*

5h 55m

Average total duration

5h 25m

Onboard

+

30m

Additional time*

3h 34m

Average total duration

(door-to-door)

0.3 - 0.7kg

CO2 emissions

0.1 - 0.3kg

CO2 emissions

Lowest

-

CO2 emissions

FlixBus

Most popular bus company

České dráhy

Most popular train company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Karlovy Vary to Brno is a bus with an average price of $14 (€11).

This is compared to other travel options from Karlovy Vary to Brno:

A bus is $19 (€15) less than a train for this route with tickets for a train from Karlovy Vary to Brno costing on average $32 (€27).

The fastest way to travel from Karlovy Vary to Brno is by bus with an average journey time of 5h 2m.

Other travel options to Brno take longer:

Train takes on average 5h 25m.

It's helpful to compare your options as there are 2 ways to travel between Karlovy Vary and Brno including taking a bus and train.
We recommend using the bus as it is the most popular way to get from Karlovy Vary to Brno among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $14 (€11) compared to roughly $78 (€64) in fuel and tolls — a saving of about $64 (€53). The journey takes 5h 2m versus 3h 34m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Direct services are operated by FlixBus.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Karlovy Vary to Brno Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
03:55AM
Arrival Time
10:10AM
Duration
6h15
Departure days
Fri
Cheapest price
$17
Operator
RegioJet a.s.
Departure Time
05:00AM
Arrival Time
10:55AM
Duration
5h55
Departure days
Wed, Thu, Sat
Cheapest price
$18
Operator
FlixBus
Departure Time
05:15AM
Arrival Time
11:10AM
Duration
5h55
Departure days
Fri
Cheapest price
$13
Operator
FlixBus
Departure Time
05:55AM
Arrival Time
12:10PM
Duration
6h15
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$16
Operator
RegioJet a.s.
Departure Time
06:00AM
Arrival Time
12:00PM
Duration
6h00
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$20
Operator
FlixBus
Departure Time
06:15AM
Arrival Time
12:10PM
Duration
5h55
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$17
Operator
RegioJet a.s.
Departure Time
07:00AM
Arrival Time
12:55PM
Duration
5h55
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$20
Operator
FlixBus
Departure Time
07:30AM
Arrival Time
02:30PM
Duration
7h00
Departure days
Tue, Fri
Cheapest price
$19
Operator
RegioJet a.s.
Departure Time
08:00AM
Arrival Time
01:30PM
Duration
5h30
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$23
Operator
FlixBus
Departure Time
08:30AM
Arrival Time
03:30PM
Duration
7h00
Departure days
Mon, Tue
Cheapest price
$9
Operator
FlixBus
Departure Time
09:30AM
Arrival Time
04:05PM
Duration
6h35
Departure days
Wed, Thu, Fri, Sat, Sun
Cheapest price
$17
Operator
RegioJet a.s.
Departure Time
10:00AM
Arrival Time
03:55PM
Duration
5h55
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$20
Operator
RegioJet a.s.
Departure Time
11:00AM
Arrival Time
04:55PM
Duration
5h55
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$20
Operator
FlixBus
Departure Time
11:30AM
Arrival Time
05:10PM
Duration
5h40
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$18
Operator
FlixBus
Departure Time
12:30PM
Arrival Time
06:05PM
Duration
5h35
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$17
Operator
RegioJet a.s.
Departure Time
01:00PM
Arrival Time
06:55PM
Duration
5h55
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$20
Operator
RegioJet a.s.
Departure Time
02:00PM
Arrival Time
07:55PM
Duration
5h55
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$18
Operator
RegioJet a.s.
Departure Time
03:00PM
Arrival Time
08:30PM
Duration
5h30
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$20
Operator
FlixBus
Departure Time
03:10PM
Arrival Time
08:00PM
Duration
4h50
Departure days
Tue
Cheapest price
$16
Operator
RegioJet a.s.
Departure Time
04:00PM
Arrival Time
09:55PM
Duration
5h55
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$24
Operator
FlixBus
Departure Time
04:10PM
Arrival Time
09:00PM
Duration
4h50
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$15
Operator
FlixBus
Departure Time
04:30PM
Arrival Time
11:05PM
Duration
6h35
Departure days
Tue
Cheapest price
$10
Operator
RegioJet a.s.
Departure Time
05:00PM
Arrival Time
10:55PM
Duration
5h55
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$21
Operator
RegioJet a.s.
Departure Time
08:00PM
Arrival Time
01:30AM
Duration
5h30
Departure days
Wed, Thu, Sat, Sun
Cheapest price
$21
Operator
FlixBus
Departure Time
08:30PM
Arrival Time
01:55AM
Duration
5h25
Departure days
Sat, Sun
Cheapest price
$17

Live departures

Karlovy Vary to Brno bus times

The table below shows live departures for Karlovy Vary to Brno buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBus7:30 AM Karlovy Vary
7h00
2:30 PM Brno0 transfersDirect
FlixBus9:30 AM Karlovy Vary
6h35
4:05 PM Brno0 transfersDirect
Saturday, June 20
RegioJet a.s.(Karlovy Vary -> Prague) · (Prague -> Brno)5:00 AM Karlovy Vary, Dolní Nádraží
5h55
10:55 AM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
FlixBusFlixBus5:55 AM Karlovy Vary, Dolní Nádraží
6h15
12:10 PM Brno, Benešova - Grandhotel (Hlavní nádraží)0 transfersDirect
RegioJet a.s.(Cheb -> Prague) · (Prague -> Budapest)6:00 AM Karlovy Vary, Dolní Nádraží
6h00
12:00 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
FlixBusFlixBus · FlixBus6:15 AM Karlovy Vary, Dolní Nádraží
5h55
12:10 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
RegioJet a.s.(Karlovy Vary -> Prague) · (Prague -> Brno)7:00 AM Karlovy Vary, Dolní Nádraží
5h55
12:55 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer
RegioJet a.s.(Cheb -> Prague) · (Prague -> Vienna)8:00 AM Karlovy Vary, Dolní Nádraží
5h30
1:30 PM Brno, Benešova - Grandhotel (Hlavní nádraží)1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Karlovy Vary to Brno by bus or train

Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Jun 20
Sun
Jun 21
Mon
Jun 22
Tue
Jun 23
Wed
Jun 24
Thu
Jun 25
Fri
Jun 26

Why should you book Karlovy Vary to Brno buses with Omio?

FlixBus operates all buses services from Karlovy Vary to Brno.
Omio is an official ticket reseller for all your travel options from Karlovy Vary to Brno.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and train to ensure you get the best deal for traveling from Karlovy Vary to Brno.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Karlovy Vary to Brno.

Journey information

Overview: Bus from Karlovy Vary to Brno

CzechiaCzechia
CzechiaCzechia
Icon of bus

Buses from Karlovy Vary to Brno run on average 16 times per day, taking around 5h 2m. Cheap bus tickets for this journey start at $8 (€6) if you book in advance.

There are 1 buses per day. The earliest bus runs at 03:15, the last at 21:20. The fastest bus covers the 181 miles (292 km) distance in 4h 50m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
181 miles (292 km)
Average bus duration
5h 2m
Cheapest ticket price
$8 (€6)
Buses per day
16
Direct buses
1
Fastest bus
4h 50m
First bus
3:15 AM
Last bus
9:20 PM
Cheapest Month
Feb
Cheapest Day
Tue
High Season
Jan - Mar
Low Season
Oct - Dec
Busiest Day
Sat
Least Busy Day
Sun
Best time to book
1 day
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Karlovy Vary to BrnoYou can travel by bus between Karlovy Vary to Brno with FlixBus for as low as $8 (€6). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
4h 50m
Cheapest Price
$8 (€6)
FlixBus frequency
7 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Complete guide to Brno

Things to do in Brno

Discover the best of Brno — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brno trip today.

  • Must visit

Moravian Gallery in Brno

The Czech Republic’s second-largest art museum, spread across several historic buildings and known for design, modern art, and strong temporary exhibitions.

  • Must visit

Moravian Museum

A major regional museum with natural history, archaeology, and cultural collections, including exhibitions linked to Mendel and Moravian heritage.

  • Must visit

Villa Tugendhat

A UNESCO-listed modernist masterpiece by Mies van der Rohe and one of Brno’s most famous cultural sites. Visits are by guided tour and usually require advance booking.

Czech Koruna

Generally cheaper than Prague. Dining and public transport are reasonable, while central hotels cost more in peak periods.

Average meal costs

Budget
CZK 150-250 for street food or a simple lunch.
Mid-range
CZK 300-500 per person at a casual restaurant.
Fine dining
CZK 900+ per person at upscale venues.
Coffee
CZK 55-80 for a cappuccino.

Tipping culture

About 10% is standard in restaurants for good service; round up in cafés and taxis. Tell the server the total when paying by card or cash.

FAQs: Bus from Karlovy Vary to Brno

Find answers to the most common questions about traveling from Karlovy Vary to Brno by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brno, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Karlovy Vary to Brno can start from as little as $8 (€6) when you book in advance. The average bus ticket price for Karlovy Vary to Brno is $14 (€11) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Karlovy Vary to Brno is 4h 50m to travel the 181 miles (292 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Karlovy Vary to Brno leaves at 3:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Karlovy Vary to Brno leaves at 9:20 PM.
Yes, there are 1 direct buses a day from Karlovy Vary to Brno with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Karlovy Vary to Brno, you can count on FlixBus for the best way to get you to Brno. You can also check all possible bus companies who offer a service between Karlovy Vary and Brno and compare the amenities they offer before buying a bus ticket.
When departing from Karlovy Vary , you have various bus station options to start your journey from including Karlovy Vary, Dolní Nádraží, Sokolov, Těšovice . When arriving in Brno , you can end your journey in bus stations like Brno, Benešova - Grandhotel (Hlavní nádraží) .Passengers board the bus most frequently from Karlovy Vary, Dolní Nádraží, which is located around away from the city centre, and they get off the bus at Brno, Benešova - Grandhotel (Hlavní nádraží), located 0 away from the city centre.
A trip to Brno from Karlovy Vary is worth doing but not as a day trip with a journey time of 4h 50m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Karlovy Vary to Brno is February.
It's helpful to compare your options as there are 2 ways to travel between Karlovy Vary and Brno including taking a bus and train.
Yes, there are bathrooms on board the bus from Karlovy Vary to Brno for bus company FlixBus.
Yes, the following accessibility options are available when taking the bus from Karlovy Vary to Brno:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Some of the most interesting sights to explore in Brno are:
  • Špilberk Castle, a historic fortress offering panoramic views of the city and housing a museum
  • Cathedral of St. Peter and Paul, a striking Gothic cathedral known for its twin spires and rich history
  • Villa Tugendhat, a UNESCO World Heritage site showcasing modernist architecture by Mies van der Rohe
  • Brno Underground, a network of historical tunnels and cellars beneath the city center
  • Moravian Museum, the second-largest museum in the Czech Republic, featuring diverse exhibits on natural history and culture.
The best things to do in Brno include:
  • Moravian Karst, a natural reserve with stunning caves and hiking trails located just outside the city
  • Brno Technical Museum, an interactive museum featuring exhibits on the history of technology and industry in the region
  • Mendel Museum, dedicated to the life and work of Gregor Mendel, the father of genetics
  • Lužánky Park, the oldest public park in Brno, perfect for a leisurely stroll or a picnic
  • Brno Zoo, offering a fun and educational experience with a variety of animal species.
Whether you can cancel your bus ticket from Karlovy Vary to Brno depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Karlovy Vary to Brno.
Yes, the following luggage options are included when booking a bus ticket from Karlovy Vary to Brno:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Karlovy Vary to Brno:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Karlovy Vary to Brno. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Karlovy Vary to Brno with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Karlovy Vary to Brno with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Karlovy Vary to Brno with the following bus company: FlixBus.
Since both Karlovy Vary and Brno are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the bus as it is the most popular way to get from Karlovy Vary to Brno among Omio's users.
The currency used in Czechia is the Czech koruna (CZK). While many places accept card payments, cash is still widely used, especially in smaller shops and markets, so travelers should carry some cash but can also use cards conveniently in most urban areas.
In Brno, travelers should be cautious of pickpocketing, especially in crowded areas like public transport and popular tourist spots. Avoid unlicensed taxi services to prevent overcharging. Be wary of distraction scams near major attractions and keep an eye on personal belongings in busy markets or events. Overall, standard urban safety precautions apply.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Karlovy Vary to Brno

Most Karlovy Vary to Brno buses use the Karlovy Vary, Dolní Nádraží to Brno, Benešova - Grandhotel (Hlavní nádraží) station pair. Use this guide to compare Karlovy Vary and Brno bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Karlovy Vary
Arrival bus stations in Brno

Which Karlovy Vary station do buses to Brno leave from?

Buses from Karlovy Vary to Brno leave from Karlovy Vary, Dolní Nádraží. The station is 0 miles (1 km) from Karlovy Vary city centre at Zapadni 2, 360 01 Karlovy Vary, Czech Republic.
Karlovy Vary, Dolní NádražíZapadni 2, 360 01 Karlovy Vary, Czech RepublicWifiParkingDiningATMAccessibilityWCTicket Office
City-centre transport

Getting to Karlovy Vary, Dolní Nádraží from Karlovy Vary city centre

Train145 · 2m
Bus854 · 5m · $2 · every ~1 min

Karlovy Vary, Dolní Nádraží bus station facilities and services

Karlovy Vary, Dolní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Accessibility, WC, and Ticket Office.

Food and drink

Food options include: Cafeteria Dolní (in the station), Fast Food Express (in the station), Coffee Corner (in the station).

Wi-Fi and ATMs

Free Wi-Fi. ATMs are located near the entrance.

Tickets and information

Ticket office support is available at Karlovy Vary, Dolní Nádraží.

Parking, taxis and toilets

Available at Karlovy Vary, Dolní Nádraží: Parking, WC.

Accessibility

Accessibility facilities are available at Karlovy Vary, Dolní Nádraží: Elevators, ramps.

More options for your journey from Karlovy Vary to Brno

Here are some other resources that might have the information you need

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