- Must visit
Bowers Museum
Major Orange County museum campus with art exhibitions, family programs, and rotating contemporary and historical shows.
Flights from Portland, OR to Santa Ana, CA depart on average 91 times per day, taking around 4h 44m. Cheap flight tickets for this journey start at $276 but you can travel from only $113 by bus.
There are 6 flights per day. The earliest flight runs at 00:09, the last at 23:58. The fastest flight covers the 852 miles (1372 km) distance in 2h 31m. November is the cheapest month to fly.
Distance 852 miles (1372 km) |
Average flight duration 4h 44m |
Cheapest ticket price $276 |
Flights per day 91 |
Direct flights 6 |
Fastest flight 2h 31m |
First flight 12:09 AM |
Last flight 11:58 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Omio recommends booking the flight as it is the most popular option from Portland, OR to Santa Ana, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $174 For those with little time, consider booking a flight, which has an average total journey time of 6h 44m. Average ticket prices depend on the travel mode: a bus costs an average of $174, while a flight costs an average of $712.
Distance: 852 miles (1372 km)
Most popular Flight | Train | Bus |
|---|---|---|
$712 Average price | $298 Average price | $174 Average price Cheapest |
6h 44m Average total duration Fastest 4h 44m Onboard + 2h 0m Additional time* | 32h 9m Average total duration 31h 39m Onboard + 30m Additional time* | 26h 1m Average total duration 25h 31m Onboard + 30m Additional time* |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Portland, OR to Santa Ana, CA:
A bus is $124 less than a train for this route with tickets for a train from Portland, OR to Santa Ana, CA costing on average $298.
A bus is $538 less than a flight for this route with tickets for a flight from Portland, OR to Santa Ana, CA costing on average $712.
Other travel options to Santa Ana, CA take longer:
Bus takes on average 25h 31m.
Train takes on average 31h 39m.
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Santa Ana, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Santa Ana, CA trip today.
Major Orange County museum campus with art exhibitions, family programs, and rotating contemporary and historical shows.
Hands-on science museum with interactive exhibits, a Discovery Cube, and family-friendly learning in downtown Santa Ana.
Small local museum preserving Orange County aviation and aerospace history with artifacts, photos, and volunteer-led interpretation.
Walkable downtown district with historic buildings, murals, shops, galleries, and regular arts and community events.
Lively pedestrian-friendly arts corridor known for galleries, murals, boutiques, and monthly art-focused street activity.
Historic neighborhood of preserved early 20th-century homes, ideal for architecture walks and seasonal house tours.
Find answers to the most common questions about traveling from Portland, OR to Santa Ana, CA by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Santa Ana, CA, this guide helps you travel smarter and with confidence.

Most Portland, OR to Santa Ana, CA flights use the Portland International Airport to John Wayne Airport airport pair. Use this guide to compare Portland, OR and Santa Ana, CA airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Portland International Airport is 8 km from Portland city centre. Public transport options include:
Portland International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants in concourses, including Burgerville and Mo's Seafood
Free Wi-Fi available throughout the airport. ATMs are located throughout the airport.
Lost and found is available at the station.
Available at Portland International Airport: Parking, Taxis, WC.
Available at Portland International Airport: Car Rental.
Accessibility facilities are available at Portland International Airport: Ramps, assistance.
Nearby hotels include Hotels nearby, including Sheraton Portland Airport Hotel..
John Wayne Airport is 3 km from Santa Ana city centre. Public transport options include:
John Wayne Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Located in terminals; options include fast food and sit-down restaurants like McDold's and Ruby's Diner
Free Wi-Fi available throughout the airport. ATMs are located in all terminals.
Lost and found is available at the station.
Available at John Wayne Airport: Parking, Taxis, WC.
Available at John Wayne Airport: Car Rental.
Accessibility facilities are available at John Wayne Airport: Elevators, ramps.
Nearby hotels include Hotels within walking distance, Hilton Irvine/Orange County Airport..
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