- Must visit
Villa Tugendhat
Modernist villa by Mies van der Rohe, listed by UNESCO. An essential architecture visit for its groundbreaking open-plan interior.
Cheapest price
$15
Average price
$20
Fastest journey
4 h
Average duration
4 h 20 m
Buses per day
5
Distance
241 km
The best way to find a cheap bus ticket from Plzeň to Brno is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Plzeň to Brno will cost around $20 if you buy it on the day, but the cheapest tickets can be found for only $15.
Of the 5 buses that leave Plzeň for Brno on Wed, Aug 05, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct buses cover the 241 km distance in an average of 4 h 20 m but if you time it right, some buses will get you there in just 4 h .
On Wed, Aug 05 the slowest buses will take 4 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus
000217
000217
FlixBus
000217
000217
FlixBus
FlixBusOmio recommends booking the bus as it is the most popular option from Plzeň to Brno among Omio's users. If you are prioritising price take the bus with prices starting from $5. For those with little time consider booking a train which can get you there in 4h 19m. The ticket price range depends on the travel mode: a bus costs an average of $5, and a train costs an average of $12.
Distance: 149 miles (241 km)
Most popular Bus | Train | Driving |
|---|---|---|
$15 Average price Cheapest | $28 Average price | $70 Average price (fuel + tolls) |
4h 52m Average total duration 4h 22m Onboard + 30m Additional time* | 4h 49m Average total duration Fastest 4h 19m Onboard + 30m Additional time* | 3h 0m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Plzeň to Brno:
A bus is $12 (€10) less than a train for this route with tickets for a train from Plzeň to Brno costing on average $28 (€23).
Other travel options to Brno take longer:
Bus takes on average 4h 22m.
Tickets start at around $15 (€13) compared to roughly $70 (€57) in fuel and tolls — a saving of about $55 (€45). The journey takes 4h 22m versus 3h 0m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by A-Express, FlixBus, Slovak Lines Express a.s., Slovak Lines Express, Infobus, LeviTour.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator AMI-Tour | Departure Time 12:00AM | Arrival Time 04:00AM | Duration 4h00 | Departure days Tue | Cheapest price $172 |
Operator FlixBus | Departure Time 12:50AM | Arrival Time 04:50AM | Duration 4h00 | Departure days Sat, Sun | Cheapest price $14 |
Operator FlixBus | Departure Time 01:50AM | Arrival Time 05:50AM | Duration 4h00 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $15 |
Operator FlixBus | Departure Time 05:15AM | Arrival Time 11:00AM | Duration 5h45 | Departure days Thu | Cheapest price $28 |
Operator FlixBus | Departure Time 05:50AM | Arrival Time 10:20AM | Duration 4h30 | Departure days Sun | Cheapest price $20 |
Operator FlixBus | Departure Time 06:45AM | Arrival Time 11:20AM | Duration 4h35 | Departure days Mon, Tue, Wed, Fri | Cheapest price $15 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 11:20AM | Duration 4h30 | Departure days Mon, Tue, Wed, Fri | Cheapest price $15 |
Operator FlixBus | Departure Time 09:10AM | Arrival Time 02:40PM | Duration 5h30 | Departure days Thu | Cheapest price $28 |
Operator A-Express | Departure Time 03:35PM | Arrival Time 07:50PM | Duration 4h15 | Departure days Sun | Cheapest price $28 |
Operator A-Express | Departure Time 05:30PM | Arrival Time 09:50PM | Duration 4h20 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $25 |
Operator A-Express | Departure Time 05:35PM | Arrival Time 09:50PM | Duration 4h15 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $25 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 11:55PM | Duration 5h45 | Departure days Sat | Cheapest price $17 |
Operator FlixBus | Departure Time 07:10PM | Arrival Time 12:55AM | Duration 5h45 | Departure days Sat, Sun | Cheapest price $7 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 03:50AM | Duration 4h00 | Departure days Fri, Sat | Cheapest price $17 |
The table below shows live departures for Plzeň to Brno buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
000217 | 5:30 PM Plzeň, Centrální Autobusové Nádraží | 4h20 | 9:50 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 0 transfersDirect | |
000217 | 5:35 PM Plzeň, Divadlo Alfa | 4h15 | 9:50 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 0 transfersDirect | |
| Wednesday, August 5 | |||||
FlixBus | 1:50 AM Plzeň, Centrální Autobusové Nádraží | 4h00 | 5:50 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 0 transfersDirect | |
FlixBus | 6:45 AM Plzeň, Centrální Autobusové Nádraží | 4h35 | 11:20 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 0 transfersDirect | |
FlixBus | 6:50 AM Plzeň, Divadlo Alfa | 4h30 | 11:20 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 0 transfersDirect | |
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Plzeň to Brno run on average 6 times per day, taking around 4h 22m. Cheap bus tickets for this journey start at $5 (€4) if you book in advance.
There are 5 buses per day. The earliest bus runs at 01:05, the last at 20:10. The fastest bus covers the 149 miles (241 km) distance in 4h 0m.
Distance 149 miles (241 km) |
Average bus duration 4h 22m |
Cheapest ticket price $5 (€4) |
Buses per day 6 |
Direct buses 5 |
Fastest bus 4h 0m |
First bus 1:05 AM |
Last bus 8:10 PM |
Cheapest Month Mar |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Tue |
Best time to book 1 day |
Discover the best of Brno — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brno trip today.
Modernist villa by Mies van der Rohe, listed by UNESCO. An essential architecture visit for its groundbreaking open-plan interior.
Brno’s city museum inside Špilberk Castle, covering local history, art, and prison heritage in a dramatic hilltop complex.
Major regional museum with natural science, history, and temporary exhibitions. A strong choice for understanding Moravia in context.
Brno’s main central square, lined with historic facades, events, and public art. A practical meeting point and key place to feel the city.
Historic market square with colorful townhouses, the Parnas fountain, and regular produce and festive markets. One of Brno’s liveliest areas.
Prominent hill around the cathedral, with calm lanes and viewpoints over the old town. Ideal for short walks and classic Brno panoramas.
Brno's classic bun filled with whipped cream. It is a beloved local pastry tied to the city's café culture and everyday sweet eating.
Pork schnitzel with potato salad is a Czech staple widely loved in Brno for family meals, pubs, and festive gatherings.
Roast beef in creamy root vegetable sauce with bread dumplings. A cornerstone Czech dish commonly served in traditional Brno restaurants.
Fine dining restaurant with modern Czech and Central European tasting menus in an elegant, contemporary setting.
Well-known restaurant and wine bar focused on Moravian ingredients, seasonal cooking, and a polished but relaxed atmosphere.
Traditional Brno restaurant by Špilberk Castle known for Czech dishes, local beer, and a historic cellar atmosphere.
More affordable than Prague and many Western European cities. Dining and transit are low-cost, while central hotels are moderate in peak periods.
Service is often not included. Round up or tip 5-10% in restaurants. Round up small taxi fares and leave small change in cafes if service is good.
Official public transport app
Brno, Benešova - Grandhotel (Hlavní nádraží) -> Náměstí Svobody, Brno
Find answers to the most common questions about traveling from Plzeň to Brno by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brno, this guide helps you travel smarter and with confidence.

Most Plzeň to Brno buses use the Plzeň, Centrální Autobusové Nádraží to Brno, Benešova - Grandhotel (Hlavní nádraží) station pair, with some services arriving at Brno, ÚAN Zvonařka. Use this guide to compare Plzeň and Brno bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Brno, Benešova - Grandhotel (Hlavní nádraží) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located inside the station.
Ticket office support is available at Brno, Benešova - Grandhotel (Hlavní nádraží).
Available at Brno, Benešova - Grandhotel (Hlavní nádraží): Parking, Taxis, WC.
Accessibility facilities are available at Brno, Benešova - Grandhotel (Hlavní nádraží): Elevators, ramps.
Here are some other resources that might have the information you need