The cheapest and fastest buses from Plzeň to Brno
Cheapest price
$22
Average price
$30
Fastest journey
4 h
Average duration
4 h 20 m
Buses per day
7
Distance
241 km
The best way to find a cheap bus ticket from Plzeň to Brno is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Plzeň to Brno will cost around $30 if you buy it on the day, but the cheapest tickets can be found for only $22.
Of the 7 buses that leave Plzeň for Brno on Sun, Dec 21, 6 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Dec 21 the direct buses cover the 241 km distance in an average of 4 h 20 m but if you time it right, some buses will get you there in just 4 h .
On Sun, Dec 21 the slowest buses will take 4 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


FlixBus
FlixBus
FlixBus
FlixBus

FlixBus
FlixBusPlzeň - BrnoCompare A-Express, FlixBus, Slovak Lines Express



Travel Information
Compare train and bus for Plzeň to Brno
Omio recommends booking the bus as it is the most popular option from Plzeň to Brno among Omio's users. If you are prioritising price take the bus with prices starting from €11. For those with little time consider booking a bus which can get you there in 4h 15m. The ticket price range depends on the travel mode: a bus costs an average of €11, and a train costs an average of €18.
Distance: 149 miles (241 km)
Compare bus with
Most popular Bus | Train |
|---|---|
€16 Average price Cheapest | €24 Average price |
4h 45m Average total duration Fastest 4h 15m Onboard + 30m Additional time* | 5h 16m Average total duration 4h 46m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Plzeň to Brno Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Infobus | Departure Time 12:00AM | Arrival Time 04:00AM | Duration 4h00 | Departure days Tue | Cheapest price $205 |
Operator FlixBus | Departure Time 01:50AM | Arrival Time 05:50AM | Duration 4h00 | Departure days Tue, Wed, Sat, Sun | Cheapest price $29 |
Operator Slovak Lines Express | Departure Time 05:45AM | Arrival Time 10:35AM | Duration 4h50 | Departure days Tue, Sat, Sun | Cheapest price $38 |
Operator FlixBus | Departure Time 06:45AM | Arrival Time 11:20AM | Duration 4h35 | Departure days Tue, Wed, Sat, Sun | Cheapest price $28 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 11:20AM | Duration 4h30 | Departure days Tue, Wed, Sat, Sun | Cheapest price $28 |
Operator A-Express | Departure Time 05:30PM | Arrival Time 09:50PM | Duration 4h20 | Departure days Tue, Sat, Sun | Cheapest price $22 |
Operator A-Express | Departure Time 05:35PM | Arrival Time 09:50PM | Duration 4h15 | Departure days Tue, Sat, Sun | Cheapest price $22 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 01:55AM | Duration 5h45 | Departure days Sat, Sun | Cheapest price $28 |
Live departures
Plzeň to Brno bus times
The table below shows live departures for Plzeň to Brno buses for today, Saturday, December 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 7:10 PM Plzeň, Centrální Autobusové Nádraží | 5h45 | 12:55 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 1 transfer | |
| Sunday, December 21 | |||||
FlixBus | 12:50 AM Plzeň, Centrální Autobusové Nádraží | 4h00 | 4:50 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 0 transfersDirect | |
0 | 4:45 AM Plzen, Centralni Autobusove Nadrazi | 4h50 | 9:35 AM Brno, ÚAN Zvonařka | 0 transfersDirect | |
FlixBus | 5:45 AM Plzeň, Centrální Autobusové Nádraží | 4h35 | 10:20 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 0 transfersDirect | |
FlixBus | 5:50 AM Plzeň, Divadlo Alfa | 4h30 | 10:20 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Plzeň to Brno by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 21
Dec 22
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
Dec 28
Dec 29
Dec 30
Dec 31
Jan 01
Jan 02
Jan 03
Journey information
Overview: Bus from Plzeň to Brno
Buses from Plzeň to Brno run on average 6 times per day, taking around 4h 15m. Cheap bus tickets for this journey start at $14 (€11) if you book in advance.
There are 5 buses per day. The earliest bus runs at 01:05, the last at 20:10. The fastest bus covers the 149 miles (241 km) distance in 4h 20m.
Distance 149 miles (241 km) |
Average bus duration 4h 15m |
Cheapest ticket price $14 (€11) |
Buses per day 6 |
Direct buses 5 |
Fastest bus 4h 20m |
First bus 01:05 |
Last bus 20:10 |
Bus providers: A-Express, FlixBus, Slovak Lines Express from Plzeň to BrnoYou can travel by bus between Plzeň to Brno with A-Express, FlixBus, Slovak Lines Express for as low as $14 (€11). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Slovak Lines Express
A-Express
FAQs: Bus from Plzeň to Brno
Find answers to the most common questions about traveling from Plzeň to Brno by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brno, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Slovak Lines Express
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Špilberk Castle, a historic fortress offering panoramic views of the city and housing a museum
- Cathedral of St. Peter and Paul, a striking Gothic cathedral known for its twin spires and rich history
- Villa Tugendhat, a UNESCO World Heritage site showcasing modernist architecture by Mies van der Rohe
- Brno Underground, a network of historical tunnels and cellars beneath the city center
- Moravian Museum, the second-largest museum in the Czech Republic, featuring diverse exhibits on natural history and culture.
- Moravian Karst, a natural reserve with stunning caves and hiking trails located just outside the city
- Brno Technical Museum, an interactive museum featuring exhibits on the history of technology and industry in the region
- Mendel Museum, dedicated to the life and work of Gregor Mendel, the father of genetics
- Lužánky Park, the oldest public park in Brno, perfect for a leisurely stroll or a picnic
- Brno Zoo, offering a fun and educational experience with a variety of animal species.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Slovak Lines Express
- You can cancel your ticket up to 24 hours before departure for a full refund. No refunds for cancellations within 24 hours.
To find the cheapest bus tickets for your trip from Plzeň to Brno, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Slovak Lines Express
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Slovak Lines Express
- 5€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
- Slovak Lines Express
- Small pets allowed in carriers
- Larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Plzeň to Brno
- 00:00-23:59
- Free Wi-Fi
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 40, 61, 67 Tram: 1, 2, 4, 8, 9, 10, 12 Train: S2, S3, S6
Most popular bus connections from Plzeň
More options for your journey from Plzeň to Brno
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