- Must visit
Villa Tugendhat
Modernist villa by Mies van der Rohe, listed by UNESCO. An essential architecture visit for its groundbreaking open-plan interior.
The best way to find a cheap bus ticket from Plzeň to Brno is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Plzeň to Brno will cost around $44 if you buy it on the day, but the cheapest tickets can be found for only $14.
On Tue, Nov 03, we found 6 buses from Plzeň to Brno, including 6 direct services.
On Tue, Nov 03 the direct buses cover the 241 km distance in an average of 4 h 13 m but if you time it right, some buses will get you there in just 4 h .
On Tue, Nov 03 the slowest buses will take 4 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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Buses from Plzeň to Brno run on average 5 times per day, taking around 4h 24m. Cheap bus tickets for this journey start at $11 but you can travel from only $11 by train.
There are 4 buses per day. The earliest bus runs at 01:05, the last at 20:10. The fastest bus covers the 149 miles (241 km) distance in 4h 0m.
Distance 149 miles (241 km) |
Average bus duration 4h 24m |
Cheapest ticket price $11 |
Buses per day 5 |
Direct buses 4 |
Fastest bus 4h 0m |
First bus 1:05 AM |
Last bus 8:10 PM |
Cheapest Month Sep |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Tue |
Best time to book 2 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Plzeň to Brno.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator AMI-Tour | Departure Time 12:00AM | Arrival Time 04:00AM | Duration 4h00 | Departure days Tue | Cheapest price $168 |
Operator FlixBus | Departure Time 12:50AM | Arrival Time 04:50AM | Duration 4h00 | Departure days Sat | Cheapest price $17 |
Operator FlixBus | Departure Time 01:50AM | Arrival Time 05:50AM | Duration 4h00 | Departure days Tue, Sun | Cheapest price $14 |
Operator FlixBus | Departure Time 05:15AM | Arrival Time 11:00AM | Duration 5h45 | Departure days Thu | Cheapest price $14 |
Operator FlixBus | Departure Time 05:35AM | Arrival Time 11:55AM | Duration 6h20 | Departure days Wed, Thu | Cheapest price $11 |
Operator FlixBus | Departure Time 05:50AM | Arrival Time 10:20AM | Duration 4h30 | Departure days Fri | Cheapest price $15 |
Operator FlixBus | Departure Time 06:45AM | Arrival Time 11:20AM | Duration 4h35 | Departure days Tue, Sun | Cheapest price $14 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 11:20AM | Duration 4h30 | Departure days Tue, Sun | Cheapest price $14 |
Operator FlixBus | Departure Time 09:10AM | Arrival Time 02:40PM | Duration 5h30 | Departure days Mon, Wed, Thu | Cheapest price $11 |
Operator A-Express | Departure Time 03:35PM | Arrival Time 07:50PM | Duration 4h15 | Departure days Fri | Cheapest price $26 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 12:05AM | Duration 7h20 | Departure days Fri | Cheapest price $9 |
Operator A-Express | Departure Time 05:30PM | Arrival Time 09:50PM | Duration 4h20 | Departure days Mon, Tue, Wed, Sun | Cheapest price $25 |
Operator A-Express | Departure Time 05:35PM | Arrival Time 09:50PM | Duration 4h15 | Departure days Mon, Tue, Wed, Sun | Cheapest price $25 |
Operator FlixBus | Departure Time 05:45PM | Arrival Time 01:05AM | Duration 7h20 | Departure days Mon, Wed, Thu, Sun | Cheapest price $12 |
Operator FlixBus | Departure Time 06:10PM | Arrival Time 11:55PM | Duration 5h45 | Departure days Fri, Sat | Cheapest price $17 |
Operator FlixBus | Departure Time 07:10PM | Arrival Time 12:55AM | Duration 5h45 | Departure days Fri, Sat | Cheapest price $7 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 03:50AM | Duration 4h00 | Departure days Thu, Fri | Cheapest price $17 |
The table below shows live departures for Plzeň to Brno buses for tomorrow, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
7715433 | 12:00 AM Plzeň | 4h00 | 4:00 AM Brno | 0 transfersDirect | |
FlixBus | 1:50 AM Plzeň, Centrální Autobusové Nádraží | 4h00 | 5:50 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 0 transfersDirect | |
FlixBus | 6:45 AM Plzeň, Centrální Autobusové Nádraží | 4h35 | 11:20 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 0 transfersDirect | |
FlixBus | 6:50 AM Plzeň, Divadlo Alfa | 4h30 | 11:20 AM Brno, Benešova - Grandhotel (Hlavní nádraží) | 0 transfersDirect | |
000217 | 5:30 PM Plzeň, Centrální Autobusové Nádraží | 4h20 | 9:50 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 0 transfersDirect | |
000217 | 5:35 PM Plzeň, Divadlo Alfa | 4h15 | 9:50 PM Brno, Benešova - Grandhotel (Hlavní nádraží) | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Brno — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brno trip today.
Modernist villa by Mies van der Rohe, listed by UNESCO. An essential architecture visit for its groundbreaking open-plan interior.
Brno’s city museum inside Špilberk Castle, covering local history, art, and prison heritage in a dramatic hilltop complex.
Major regional museum with natural science, history, and temporary exhibitions. A strong choice for understanding Moravia in context.
Brno’s main central square, lined with historic facades, events, and public art. A practical meeting point and key place to feel the city.
Historic market square with colorful townhouses, the Parnas fountain, and regular produce and festive markets. One of Brno’s liveliest areas.
Prominent hill around the cathedral, with calm lanes and viewpoints over the old town. Ideal for short walks and classic Brno panoramas.
Brno's classic bun filled with whipped cream. It is a beloved local pastry tied to the city's café culture and everyday sweet eating.
Pork schnitzel with potato salad is a Czech staple widely loved in Brno for family meals, pubs, and festive gatherings.
Roast beef in creamy root vegetable sauce with bread dumplings. A cornerstone Czech dish commonly served in traditional Brno restaurants.
Fine dining restaurant with modern Czech and Central European tasting menus in an elegant, contemporary setting.
Well-known restaurant and wine bar focused on Moravian ingredients, seasonal cooking, and a polished but relaxed atmosphere.
Traditional Brno restaurant by Špilberk Castle known for Czech dishes, local beer, and a historic cellar atmosphere.
More affordable than Prague and many Western European cities. Dining and transit are low-cost, while central hotels are moderate in peak periods.
Service is often not included. Round up or tip 5-10% in restaurants. Round up small taxi fares and leave small change in cafes if service is good.
Official public transport app
Brno, Benešova - Grandhotel (Hlavní nádraží) -> Náměstí Svobody, Brno
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Brno.
Find answers to the most common questions about traveling from Plzeň to Brno by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brno, this guide helps you travel smarter and with confidence.

Most Plzeň to Brno buses use the Plzeň, Centrální Autobusové Nádraží to Brno, Benešova - Grandhotel (Hlavní nádraží) station pair, with some services arriving at Brno, ÚAN Zvonařka. Use this guide to compare Plzeň and Brno bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Plzeň, Divadlo Alfa is 1 km from Plzeň city centre. Public transport options include:
Plzeň, Divadlo Alfa has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Plzeň, Divadlo Alfa. ATMs are available at Plzeň, Divadlo Alfa.
Ticket office support is available at Plzeň, Divadlo Alfa.
Available at Plzeň, Divadlo Alfa: Parking, Taxis, WC.
Accessibility facilities are available at Plzeň, Divadlo Alfa: Wheelchair accessible paths.
Plzen, Centralni Autobusove Nadrazi is 5 km from Plzeň city centre. Public transport options include:
Plzen, Centralni Autobusove Nadrazi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bars available.
Wi-Fi is available at Plzen, Centralni Autobusove Nadrazi. ATMs are aTM available near the main entrance.
Ticket office support is available at Plzen, Centralni Autobusove Nadrazi.
Available at Plzen, Centralni Autobusove Nadrazi: Parking, Taxis, WC.
Accessibility facilities are available at Plzen, Centralni Autobusove Nadrazi: Accessible for passengers with reduced mobility.
Brno, Benešova - Grandhotel (Hlavní nádraží) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, and Ticket Office.
Free Wi-Fi. ATMs are located inside the station.
Ticket office support is available at Brno, Benešova - Grandhotel (Hlavní nádraží).
Available at Brno, Benešova - Grandhotel (Hlavní nádraží): Parking, Taxis, WC.
Accessibility facilities are available at Brno, Benešova - Grandhotel (Hlavní nádraží): Elevators, ramps.
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