The cheapest and fastest buses from Plzeň to Frankfurt am Main
Cheapest price
$43
Average price
$49
Fastest journey
5 h 5 m
Average duration
5 h 59 m
Buses per day
9
Distance
338 km
The best way to find a cheap bus ticket from Plzeň to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Plzeň to Frankfurt am Main will cost around $49 if you buy it on the day, but the cheapest tickets can be found for only $43.
Of the 9 buses that leave Plzeň for Frankfurt am Main on Fri, May 29, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, May 29 the direct buses cover the 338 km distance in an average of 5 h 59 m but if you time it right, some buses will get you there in just 5 h 5 m .
On Fri, May 29 the slowest buses will take 6 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus12:20 PM7h05Plzeň, Centrální Autobusové Nádraží7:25 PMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$431One-way0 transfers
FlixBus · FlixBus11:55 PM6h05Plzeň, Centrální Autobusové Nádraží6:00 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$491One-way1 transfer
FlixBus · FlixBus4:40 PM8h30Plzeň, Centrální Autobusové Nádraží1:10 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$491One-way1 transfer
(Prague -> Amsterdam)12:20 AM5h05Plzeň, Centrální Autobusové Nádraží5:25 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$501One-way0 transfers
(Prague -> Amsterdam)12:20 AM5h35Plzeň, Centrální Autobusové Nádraží5:55 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$501One-way0 transfers
(Prague -> Amsterdam)12:20 AM5h05Plzeň, Centrální Autobusové Nádraží5:25 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$501One-way0 transfers
(Prague -> Amsterdam)12:20 AM5h35Plzeň, Centrální Autobusové Nádraží5:55 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$501One-way0 transfers
FlixBus · FlixBus11:55 PM6h05Plzeň, Centrální Autobusové Nádraží6:00 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$491One-way1 transfer
FlixBus · FlixBus11:55 PM6h35Plzeň, Centrální Autobusové Nádraží6:30 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$501One-way1 transfer
FlixBus12:20 PM6h35Plzeň, Centrální Autobusové Nádraží6:55 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$511One-way0 transfers
Travel Information
Compare train, bus, and flight for Plzeň to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Plzeň to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a flight which can get you there in 1h 10m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $100.
Distance: 210 miles (338 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$37 Average price Cheapest | $86 Average price | $201 Average price | $95 Average price (fuel + tolls) |
5h 54m Average total duration 5h 24m Onboard + 30m Additional time* | 5h 56m Average total duration 5h 26m Onboard + 30m Additional time* | 4h 10m Average total duration Fastest 1h 10m Onboard + 3h 0m Additional time* | 3h 58m Average total duration (door-to-door) |
0.3 - 0.8kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.0 - 2.0kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Plzeň to Frankfurt am Main:
A bus is $49 (€40) less than a train for this route with tickets for a train from Plzeň to Frankfurt am Main costing on average $86 (€69).
A bus is $164 (€132) less than a flight for this route with tickets for a flight from Plzeň to Frankfurt am Main costing on average $201 (€162).
Other travel options to Frankfurt am Main take longer:
Bus takes on average 5h 24m.
Train takes on average 5h 26m.
Tickets start at around $37 (€30) compared to roughly $95 (€76) in fuel and tolls — a saving of about $58 (€47). The journey takes 5h 24m versus 3h 58m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Plzeň to Frankfurt am Main Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator RegioJet a.s. | Departure Time 12:20AM | Arrival Time 05:55AM | Duration 5h35 | Departure days Thu, Fri, Sun | Cheapest price $37 |
Operator FlixBus | Departure Time 01:20AM | Arrival Time 09:20AM | Duration 8h00 | Departure days Fri | Cheapest price $53 |
Operator FlixBus | Departure Time 10:20AM | Arrival Time 05:25PM | Duration 7h05 | Departure days Mon, Tue, Wed, Sat | Cheapest price $29 |
Operator FlixBus | Departure Time 11:20AM | Arrival Time 06:25PM | Duration 7h05 | Departure days Mon, Tue, Wed, Sat | Cheapest price $29 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 07:25PM | Duration 7h05 | Departure days Thu, Fri, Sun | Cheapest price $35 |
Operator FlixBus | Departure Time 03:40PM | Arrival Time 12:35AM | Duration 8h55 | Departure days Wed | Cheapest price $37 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 12:20AM | Duration 7h40 | Departure days Thu, Fri, Sun | Cheapest price $43 |
Operator FlixBus | Departure Time 08:45PM | Arrival Time 07:15AM | Duration 10h30 | Departure days Tue | Cheapest price $37 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 07:15AM | Duration 8h20 | Departure days Wed | Cheapest price $42 |
Operator FlixBus | Departure Time 11:55PM | Arrival Time 09:45AM | Duration 9h50 | Departure days Thu, Fri, Sun | Cheapest price $42 |
Live departures
Plzeň to Frankfurt am Main bus times
The table below shows live departures for Plzeň to Frankfurt am Main buses for today, Thursday, May 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:55 PM Plzeň, Centrální Autobusové Nádraží | 9h50 | 9:45 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 11:55 PM Plzeň, Centrální Autobusové Nádraží | 8h20 | 8:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
| Friday, May 29 | |||||
(Prague -> Amsterdam) | 12:20 AM Plzeň, Centrální Autobusové Nádraží | 5h35 | 5:55 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
(Prague -> Amsterdam) | 12:20 AM Plzeň, Centrální Autobusové Nádraží | 5h05 | 5:25 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus · FlixBus | 1:20 AM Plzeň, Centrální Autobusové Nádraží | 8h00 | 9:20 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
FlixBus | 12:20 PM Plzeň, Centrální Autobusové Nádraží | 7h05 | 7:25 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 0 transfersDirect | |
FlixBus | 12:20 PM Plzeň, Centrální Autobusové Nádraží | 6h35 | 6:55 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 0 transfersDirect | |
FlixBus · FlixBus | 4:40 PM Plzeň, Centrální Autobusové Nádraží | 8h55 | 1:35 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 1 transfer | |
FlixBus · FlixBus | 4:40 PM Plzeň, Centrální Autobusové Nádraží | 8h30 | 1:10 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Plzeň to Frankfurt am Main by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Jun 04
Why should you book Plzeň to Frankfurt am Main buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Plzeň to Frankfurt am Main.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Plzeň to Frankfurt am Main.
Journey information
Overview: Bus from Plzeň to Frankfurt am Main
Buses from Plzeň to Frankfurt am Main run on average 7 times per day, taking around 5h 24m. Cheap bus tickets for this journey start at $24 (€19) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:20, the last at 23:55. The fastest bus covers the 210 miles (338 km) distance in 5h 35m.
Distance 210 miles (338 km) |
Average bus duration 5h 24m |
Cheapest ticket price $24 (€19) |
Buses per day 7 |
Direct buses 3 |
Fastest bus 5h 35m |
First bus 12:20 AM |
Last bus 11:55 PM |
Cheapest Month Sep |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Thu |
Best time to book 42 days |
Bus providers: FlixBus, BlaBlaCar from Plzeň to Frankfurt am MainYou can travel by bus between Plzeň to Frankfurt am Main with FlixBus, BlaBlaCar for as low as $24 (€19). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
FAQs: Bus from Plzeň to Frankfurt am Main
Find answers to the most common questions about traveling from Plzeň to Frankfurt am Main by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Römer, a historic city hall with medieval architecture located in the heart of Frankfurt's old town
- Städel Museum, an art museum featuring a vast collection of European artworks from the Middle Ages to the present
- Palmengarten, a large botanical garden showcasing diverse plant species in themed greenhouses and outdoor areas
- Goethe House, the birthplace of the famous writer Johann Wolfgang von Goethe, now a museum dedicated to his life and works
- Frankfurt Cathedral, a Gothic-style church with a rich history and stunning architecture.
- Main Tower, a skyscraper with an observation deck providing panoramic views of the city
- Explore the vibrant Kleinmarkthalle, an indoor market offering a variety of local and international foods
- Visit the Senckenberg Natural History Museum, home to an extensive collection of dinosaur fossils and natural exhibits
- Take a leisurely walk along the River Main and enjoy the scenic views
- Experience the lively atmosphere of the Zeil, Frankfurt's premier shopping street.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Plzeň to Frankfurt am Main
- 00:00-23:59
- Free Wi-Fi
- McDonald's (in the station)
- Hausmann's (in the station).
- Available outside the terminal at designated taxi stands.
- Elevators, ramps, assistance
- Available in the station.
- Bus: 61, 62, 77 Train: S8, S9
Most popular bus connections from Plzeň
More options for your journey from Plzeň to Frankfurt am Main
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