- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
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Travel Information
Compare bus and flight for Pisa International Airport to Brussels
Omio recommends booking the flight as it is the most popular option from Pisa International Airport to Brussels among Omio's users. If you are prioritising price, take the flight, with an average ticket price of $622 For those with little time, consider booking a flight, which has an average total journey time of 5h 50m. Average ticket prices depend on the travel mode: a flight costs an average of $622, while a flight costs an average of $622.
Distance: 569 miles (916 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$622 Average price Cheapest | $355 Average price (fuel + tolls) | |
5h 50m Average total duration Fastest 3h 50m Onboard + 2h 0m Additional time* | 11h 50m Average total duration (door-to-door) | |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Pisa International Airport to Brussels is a flight with an average price of $622 (€503).
The fastest way to travel from Pisa International Airport to Brussels is by flight with an average journey time of 3h 50m.
It's helpful to compare your options as there are 2 ways to travel between Pisa International Airport and Brussels including taking a bus and flight.
We recommend using the flight as it is the most popular way to get from Pisa International Airport to Brussels among Omio's users.
Pisa International Airport to Brussels Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:45AM | Arrival Time 08:30AM | Duration 26h45 | Departure days Fri, Sat, Sun | Cheapest price $127 |
Compare prices and tickets Pisa International Airport to Brussels by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Pisa International Airport to Brussels buses with Omio?
FlixBus operates all buses services from Pisa International Airport to Brussels.
Omio is an official ticket reseller for all your travel options from Pisa International Airport to Brussels.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Pisa International Airport to Brussels.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Pisa International Airport to Brussels.
Journey information
Overview: Bus from Pisa International Airport to Brussels
Italy
Belgium
Take a bus from Pisa International Airport to Brussels and enjoy the approximately 569 miles (916 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 05:45, the last at 05:45.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $30 (€24)
Distance 569 miles (916 km) |
First bus 5:45 AM |
Last bus 5:45 AM |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Sun |
Least Busy Day Wed |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $30 (€24)
Complete guide to Brussels
Things to do in Brussels
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
- Must visit
Magritte Museum
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
- Must visit
Comics Art Museum
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
- Must visit
Grand Place
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
- Must visit
Parc du Cinquantenaire
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
- Must visit
Mont des Arts
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Moules-Frites
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
- Vegetarian
- Gluten-free
Frites
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
Carbonnade Flamande
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Bozar Restaurant
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Brasserie La Paix
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Maison Dandoy
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Euro (€)
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Average meal costs
- Budget
- €8-15 for fast food or casual takeaway.
- Mid-range
- €20-35 per person for a standard restaurant meal.
- Fine dining
- €70+ per person for upscale restaurants.
- Coffee
- €3-5 for cappuccino or latte.
Tipping culture
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
STIB-MIVB
Get the appOfficial public transport app
Prices
- Single ticket
- €2.50
- Day pass
- €8.40
To the city center
Brussels South (Gare du Midi) -> Brussels Central Station, Brussels
- Distance
- 2 km
- Travel time
- 5 min
- Contactless bank card payment is available on STIB-MIVB trams, buses, and metro gates. Buy the cheapest fare for occasional travel this way.
- Brussels South is also called Gare du Midi or Zuidstation. Validate paper tickets before boarding or at metro gates.
FAQs: Bus from Pisa International Airport to Brussels
Find answers to the most common questions about traveling from Pisa International Airport to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
popular bus stations
Popular bus stations from Pisa International Airport to Brussels
Most Pisa International Airport to Brussels buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Brussels, Gare Du Midi. Use this guide to compare Pisa International Airport and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Pisa
Arrival bus stations in Brussels
Brussels, Brussels South (Gare du Midi)Avenue Fonsny 47, 1060 Brussels, Belgium
City-centre transport
Getting to Brussels, Brussels South (Gare du Midi) from Brussels city centre
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
TrainEuroCity · 4m · $1 · every ~2 min
Ice · 14m · $1
Bus48 · 16m · $4 · every ~9 min
Bus · 20m
FlixBus N1153 · 29m · $1
Subway2, 6 · 18m · $4 · every ~38 min
Brussels, Brussels South (Gare du Midi) bus station facilities and services
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Tickets and information
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Parking, taxis and toilets
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Brussels, Gare Du MidiBrussel-Zuid, Av. Fonsny 47B, 1060 Bruxelles, Belgium
City-centre transport
Getting to Brussels, Gare Du Midi from Brussels city centre
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
TrainEuroCity · 4m · $1 · every ~2 min
Ice · 14m · $1
Bus48 · 16m · $4 · every ~9 min
Bus · 20m
FlixBus N1153 · 29m · $1
Subway2, 6 · 18m · $4 · every ~38 min
Brussels, Gare Du Midi bus station facilities and services
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Various dining options are nearby.
Wi-Fi and ATMs
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Tickets and information
Ticket office support is available at Brussels, Gare Du Midi.
Parking, taxis and toilets
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Brussels-NoordRue du Progres 123, 1030 Schaerbeek, Brussels, Belgium
City-centre transport
Getting to Brussels-Noord from Brussels city centre
Brussels-Noord is 1 km from Brussels city centre. Public transport options include:
TrainP, S3, Ec, T, Ic, Ext, L, S1, S10, S4, S2, S8 · 4m · $1 · every ~58 min
Bus88 · 6m · $4 · every ~10 min
R24, 728, R28 · 7m · $4 · every ~10 min
Tram4, 10 · 4m · $4 · every ~34 min
10, 4 · 5m · $4 · every ~34 min
Brussels-Noord bus station facilities and services
Brussels-Noord has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Noord (in the station), Quick Brussels Noord (in the station), Le Pain Quotidien (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Tickets and information
Ticket office support is available at Brussels-Noord.
Parking, taxis and toilets
Available at Brussels-Noord: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels-Noord: Elevators, ramps.
Most popular bus connections from Pisa International Airport
More options for your journey from Pisa International Airport to Brussels
Here are some other resources that might have the information you need
Most popular buses to and from Brussels and Pisa International Airport
Most popular bus connections to Brussels
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