- Must visit
Greenville County Museum of Art
Major art museum known for its Southern art collection and works by Andrew Wyeth and Jasper Johns. One of the city’s top cultural attractions.
Omio recommends booking the train as it is the most popular option from Philadelphia, PA to Greenville, NC among Omio's users. If you are prioritising price take the bus with prices starting from $45. For those with little time consider booking a train which can get you there in 8h 13m. The ticket price range depends on the travel mode: a bus costs an average of $45, and a train costs an average of $117.
Distance: 323 miles (520 km)
| Bus | Most popular Train |
|---|---|
$88 Average price Cheapest | $159 Average price |
15h 3m Average total duration 14h 33m Onboard + 30m Additional time* | 8h 43m Average total duration Fastest 8h 13m Onboard + 30m Additional time* |
Direct Options | Direct Options |
This is compared to other travel options from Philadelphia, PA to Greenville, NC:
A bus is $71 (€57) less than a train for this route with tickets for a train from Philadelphia, PA to Greenville, NC costing on average $159 (€128).
Other travel options to Greenville, NC take longer:
Bus takes on average 14h 33m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:30AM | Arrival Time 04:30PM | Duration 16h00 | Departure days Wed, Thu | Cheapest price $83 |
Operator Greyhound | Departure Time 03:00AM | Arrival Time 05:30PM | Duration 14h30 | Departure days Sat | Cheapest price $74 |
Operator Greyhound | Departure Time 04:50AM | Arrival Time 03:00PM | Duration 10h10 | Departure days Thu, Fri | Cheapest price $124 |
Operator Greyhound | Departure Time 05:50AM | Arrival Time 04:00PM | Duration 10h10 | Departure days Thu | Cheapest price $45 |
Operator FlixBus | Departure Time 10:30PM | Arrival Time 04:30PM | Duration 18h00 | Departure days Wed | Cheapest price $65 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 05:30PM | Duration 18h00 | Departure days Thu | Cheapest price $59 |
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Philadelphia, PA to Greenville, NC run on average 4 times per day, taking around 14h 33m. Cheap bus tickets for this journey start at $45 (€36) if you book in advance.
The earliest bus runs at 00:50, the last at 23:20. The fastest bus covers the 323 miles (520 km) distance in 10h 10m.
Distance 323 miles (520 km) |
Average bus duration 14h 33m |
Cheapest ticket price $45 (€36) |
Buses per day 4 |
Fastest bus 10h 10m |
First bus 12:50 AM |
Last bus 11:20 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 35 days |
Discover the best of Greenville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville trip today.
Major art museum known for its Southern art collection and works by Andrew Wyeth and Jasper Johns. One of the city’s top cultural attractions.
Regional history museum with rotating exhibitions on the Upstate’s people, industry, and culture. A strong choice for understanding Greenville beyond downtown.
Specialized museum displaying historic string, keyboard, and wind instruments from around the world. A lesser-known but distinctive Greenville stop.
The core downtown street lined with shops, public art, plazas, and event spaces. It is Greenville’s main walking corridor and a top first stop.
Multi-use greenway linking Greenville with nearby communities. Highly popular for walking and cycling, and one of the city’s most loved outdoor assets.
Lively downtown district near Falls Park known for baseball, galleries, restored buildings, and a strong local atmosphere. Popular for strolling and photos.
Slow-smoked pork, often chopped or pulled, served with the state's famous mustard-based 'Carolina Gold' sauce. It is a defining Upstate and statewide tradition.
Unripe green tomatoes sliced, breaded, and fried until crisp. A classic Southern starter found on many Greenville-area menus.
Creamy stone-ground grits topped with shrimp, often with bacon, gravy, or a rich butter sauce. A beloved Lowcountry and broader South Carolina favorite.
Acclaimed neighborhood restaurant focused on seasonal Southern-influenced cooking, thoughtful plates, and a more polished dining experience.
A long-running downtown favorite serving refined Southern cuisine, including shrimp and grits and seasonal regional dishes, in a lively historic setting.
Stylish downtown restaurant known for handmade pasta, oysters, and city views. It is one of Greenville's best-known upscale dining rooms.
Costs are moderate by U.S. standards. Dining is reasonable, while hotels rise during events and peak weekends.
Tip 18-20% in restaurants; 20%+ for excellent service. Tip bartenders USD 1-2 per drink, taxis 10-15%, hotel staff USD 2-5, and round up for coffee if desired.
Find answers to the most common questions about traveling from Philadelphia, PA to Greenville, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Greenville, NC, this guide helps you travel smarter and with confidence.

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