- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey on Place des Terreaux, known for strong collections from antiquity to modern art.
Cheapest price
$88
Average price
$97
Fastest journey
10 h 40 m
Average duration
11 h 51 m
Buses per day
5
Distance
433 km
The best way to find a cheap bus ticket from La Spezia to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from La Spezia to Lyon will cost around $97 if you buy it on the day, but the cheapest tickets can be found for only $88.
It's difficult to get from La Spezia to Lyon without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBus
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FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from La Spezia to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $43. For those with little time consider booking a train which can get you there in 8h 30m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $43, and a train costs an average of $94.
Distance: 269 miles (433 km)
Most popular Bus | Train | Driving |
|---|---|---|
$78 Average price Cheapest | $133 Average price | $270 Average price (fuel + tolls) |
9h 10m Average total duration 8h 40m Onboard + 30m Additional time* | 9h 0m Average total duration Fastest 8h 30m Onboard + 30m Additional time* | 6h 34m Average total duration (door-to-door) |
0.4 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from La Spezia to Lyon:
A bus is $56 (€46) less than a train for this route with tickets for a train from La Spezia to Lyon costing on average $133 (€109).
Other travel options to Lyon take longer:
Train takes on average 8h 30m.
Bus takes on average 8h 40m.
Tickets start at around $78 (€63) compared to roughly $270 (€221) in fuel and tolls — a saving of about $192 (€157). The journey takes 8h 40m versus 6h 34m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:30AM | Arrival Time 12:10PM | Duration 10h40 | Departure days Tue, Thu, Fri | Cheapest price $62 |
Operator FlixBus | Departure Time 03:30AM | Arrival Time 02:10PM | Duration 10h40 | Departure days Mon, Sun | Cheapest price $76 |
Operator FlixBus | Departure Time 05:10AM | Arrival Time 04:10PM | Duration 11h00 | Departure days Tue | Cheapest price $57 |
Operator FlixBus | Departure Time 06:10AM | Arrival Time 05:10PM | Duration 11h00 | Departure days Tue | Cheapest price $43 |
Operator FlixBus | Departure Time 07:10AM | Arrival Time 06:10PM | Duration 11h00 | Departure days Mon, Sun | Cheapest price $87 |
Operator BlaBlaCar | Departure Time 09:50AM | Arrival Time 04:20PM | Duration 6h30 | Departure days Sat | Cheapest price $68 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 01:55AM | Duration 11h55 | Departure days Thu, Fri | Cheapest price $75 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 02:50AM | Duration 11h20 | Departure days Fri | Cheapest price $84 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 03:55AM | Duration 11h55 | Departure days Mon, Sun | Cheapest price $76 |
Operator FlixBus | Departure Time 05:15PM | Arrival Time 06:45AM | Duration 13h30 | Departure days Wed, Thu | Cheapest price $60 |
Operator FlixBus | Departure Time 05:30PM | Arrival Time 06:45AM | Duration 13h15 | Departure days Wed, Fri | Cheapest price $88 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 06:30AM | Duration 12h25 | Departure days Mon, Sat, Sun | Cheapest price $80 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 07:45AM | Duration 13h30 | Departure days Thu, Fri | Cheapest price $47 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 07:45AM | Duration 13h15 | Departure days Wed | Cheapest price $77 |
Operator FlixBus | Departure Time 06:50PM | Arrival Time 07:45AM | Duration 12h55 | Departure days Thu | Cheapest price $80 |
Operator FlixBus | Departure Time 07:30PM | Arrival Time 08:45AM | Duration 13h15 | Departure days Sat, Sun | Cheapest price $120 |
The table below shows live departures for La Spezia to Lyon buses for tomorrow, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 3:30 AM La Specia, Via Giosuè Carducci | 10h40 | 2:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 7:10 AM La Specia, Via Giosuè Carducci | 11h00 | 6:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 4:00 PM La Specia, Via Giosuè Carducci | 11h55 | 3:55 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 6:05 PM La Specia, Via Giosuè Carducci | 12h25 | 6:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 7:30 PM La Specia, Via Giosuè Carducci | 13h15 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer |
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from La Spezia to Lyon run on average 4 times per day, taking around 8h 40m. Cheap bus tickets for this journey start at $43 (€35) if you book in advance.
The earliest bus runs at 00:05, the last at 23:00. The fastest bus covers the 269 miles (433 km) distance in 10h 40m.
Distance 269 miles (433 km) |
Average bus duration 8h 40m |
Cheapest ticket price $43 (€35) |
Buses per day 4 |
Fastest bus 10h 40m |
First bus 12:05 AM |
Last bus 11:00 PM |
Cheapest Month Mar |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 21 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey on Place des Terreaux, known for strong collections from antiquity to modern art.
Excellent museum on Roman Lyon with mosaics, inscriptions, and artifacts beside the ancient theaters on Fourvière hill.
Striking science and society museum at the meeting of the Rhône and Saône, famous for immersive displays and architecture.
The city's atmospheric old quarter with Renaissance lanes, traboules, courtyards, and a strong UNESCO heritage feel.
One of Europe's largest open squares and a key central meeting point in Lyon's Presqu'île.
Large urban park with lake, botanical spaces, greenhouses, and broad paths for walking and relaxing.
Light dumplings traditionally made with pike and baked in a rich Nantua crayfish sauce, a classic specialty of Lyonnais cuisine.
A warm salad of frisee lettuce, lardons, croutons, and a poached egg, emblematic of Lyon's hearty bouchon cooking.
Pork sausage baked inside a soft brioche loaf, a festive and traditional Lyonnais dish often served in bouchons.
An iconic fine-dining restaurant with deep Lyon culinary heritage, serving elegant cuisine in a prestigious setting.
A respected modern bouchon offering refined takes on Lyonnais classics in a warm and polished setting.
A historic bouchon known for classic Lyonnais dishes, convivial service, and a traditional, bustling atmosphere.
Moderate by French standards: bakeries and lunch deals are good value, while central hotels and dinner spots cost more.
Service is included by law. Rounding up or leaving 5-10% for very good restaurant service is appreciated, not required. Round up taxis; small change is fine in cafés and bars.
Official public transport app
Lyon Perrache Bus Station, Lyon -> Lyon Part-Dieu Station, Lyon
Find answers to the most common questions about traveling from La Spezia to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most La Spezia to Lyon buses use the La Spezia, Via Giosuè Carducci to Lyon, Gare Routière de Perrache station pair, with some services arriving at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan). Use this guide to compare La Spezia and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Here are some other resources that might have the information you need