The cheapest and fastest buses from La Spezia to Lyon
Cheapest price
$54
Average price
$76
Fastest journey
10 h 30 m
Average duration
11 h 30 m
Buses per day
5
Distance
433 km
The best way to find a cheap bus ticket from La Spezia to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from La Spezia to Lyon will cost around $76 if you buy it on the day, but the cheapest tickets can be found for only $54.
Of the 5 buses that leave La Spezia for Lyon on Thu, Nov 06, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Nov 06 the direct buses cover the 433 km distance in an average of 11 h 30 m but if you time it right, some buses will get you there in just 10 h 30 m .
On Thu, Nov 06 the slowest buses will take 12 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare train, bus, and flight for La Spezia to Lyon
Omio recommends booking the bus as it is the most popular option from La Spezia to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €40. For those with little time consider booking a flight which can get you there in 2h 7m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €40, and a flight costs an average of €29.
Distance: 269 miles (433 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
€73 Average price Cheapest | €357 Average price | €93 Average price |
9h 2m Average total duration 8h 32m Onboard + 30m Additional time* | 5h 7m Average total duration Fastest 2h 7m Onboard + 3h 0m Additional time* | 9h 22m Average total duration 8h 52m Onboard + 30m Additional time* |
0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
La Spezia to Lyon Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Regionale | Departure Time 04:30AM | Arrival Time 12:20AM | Duration 19h50 | Departure days Tue | Cheapest price $127 |
Operator Intercity | Departure Time 04:56AM | Arrival Time 12:20AM | Duration 19h24 | Departure days Tue | Cheapest price $129 |
Operator Regionale | Departure Time 05:00AM | Arrival Time 12:20AM | Duration 19h20 | Departure days Tue | Cheapest price $127 |
Operator Intercity Notte | Departure Time 05:25AM | Arrival Time 12:20AM | Duration 18h55 | Departure days Tue | Cheapest price $129 |
Operator Regionale | Departure Time 05:40AM | Arrival Time 12:20AM | Duration 18h40 | Departure days Tue | Cheapest price $127 |
Operator Regionale | Departure Time 06:25AM | Arrival Time 12:20AM | Duration 17h55 | Departure days Tue | Cheapest price $127 |
Operator Intercity | Departure Time 06:38AM | Arrival Time 12:20AM | Duration 17h42 | Departure days Tue | Cheapest price $129 |
Operator Regionale | Departure Time 07:04AM | Arrival Time 12:20AM | Duration 17h16 | Departure days Tue | Cheapest price $127 |
Operator FlixBus | Departure Time 07:10AM | Arrival Time 06:10PM | Duration 11h00 | Departure days Tue | Cheapest price $137 |
Operator Intercity | Departure Time 07:38AM | Arrival Time 12:20AM | Duration 16h42 | Departure days Tue | Cheapest price $129 |
Operator Regionale | Departure Time 07:45AM | Arrival Time 12:20AM | Duration 16h35 | Departure days Tue | Cheapest price $127 |
Operator Regionale | Departure Time 08:12AM | Arrival Time 12:20AM | Duration 16h08 | Departure days Tue | Cheapest price $127 |
Operator Frecciargento | Departure Time 09:39AM | Arrival Time 12:20AM | Duration 14h41 | Departure days Tue | Cheapest price $135 |
Operator Regionale | Departure Time 09:57AM | Arrival Time 12:20AM | Duration 14h23 | Departure days Tue | Cheapest price $127 |
Operator Intercity | Departure Time 10:10AM | Arrival Time 12:20AM | Duration 14h10 | Departure days Tue | Cheapest price $129 |
Operator Regionale | Departure Time 10:15AM | Arrival Time 12:20AM | Duration 14h05 | Departure days Tue | Cheapest price $127 |
Operator Frecciarossa | Departure Time 10:45AM | Arrival Time 12:20AM | Duration 13h35 | Departure days Tue | Cheapest price $135 |
Operator BlaBlaCar | Departure Time 12:30PM | Arrival Time 06:40PM | Duration 6h10 | Departure days Tue | Cheapest price $56 |
Operator BlaBlaCar | Departure Time 02:00PM | Arrival Time 09:10PM | Duration 7h10 | Departure days Tue | Cheapest price $43 |
Live departures
La Spezia to Lyon bus times
The table below shows live departures for La Spezia to Lyon buses for tomorrow, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:30 AM La Spezia | 10h45 | 12:15 PM Lyon | 0 transfersDirect | |
![]() | 2:45 AM La Spezia | 10h30 | 1:15 PM Lyon | 0 transfersDirect | |
![]() | 5:10 AM La Spezia | 11h00 | 4:10 PM Lyon | 0 transfersDirect | |
![]() | 2:30 PM La Spezia | 12h45 | 3:15 AM Lyon | 0 transfersDirect | |
![]() | 4:05 PM La Spezia | 12h30 | 4:35 AM Lyon | 0 transfersDirect |
Find all the dates and times for this journey
Compare prices and tickets La Spezia to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 06
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Journey information
Overview: Bus from La Spezia to Lyon
Buses from La Spezia to Lyon run on average 4 times per day, taking around 8h 32m. Cheap bus tickets for this journey start at $50 (€40) but you can travel from only $35 (€29) by flight.
The earliest bus runs at 00:05, the last at 23:00. The fastest bus covers the 269 miles (433 km) distance in 10h 45m.
Distance 269 miles (433 km) |
Average bus duration 8h 32m |
Cheapest ticket price $50 (€40) |
Buses per day 4 |
Fastest bus 10h 45m |
First bus 00:05 |
Last bus 23:00 |
Bus providers: FlixBus, BlaBlaCar from La Spezia to LyonYou can travel by bus between La Spezia to Lyon with FlixBus, BlaBlaCar for as low as $35 (€29). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
FAQs: Bus from La Spezia to Lyon
Find answers to the most common questions about traveling from La Spezia to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Basilica of Notre-Dame de Fourvière, a stunning 19th-century basilica offering panoramic views of the city
- Vieux Lyon, a UNESCO World Heritage site known for its Renaissance architecture and narrow cobblestone streets
- Parc de la Tête d'Or, a large urban park featuring a zoo, botanical garden, and lake
- Musée des Confluences, a modern science and anthropology museum with innovative exhibits
- Place Bellecour, one of Europe's largest open squares, ideal for shopping and dining.
- Les Halles de Lyon Paul Bocuse, a renowned indoor market offering gourmet food and local specialties
- Take a river cruise on the Rhône and Saône for a unique view of the city
- Explore the traboules, secret passageways in Vieux Lyon
- Attend a performance at the Opéra de Lyon, known for its diverse program
- Visit the Institut Lumière, dedicated to the history of cinema.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from La Spezia to Lyon, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from La Spezia to Lyon
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Most popular bus connections from La Spezia
More options for your journey from La Spezia to Lyon
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