- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price on Sep 19
$61
Average ticket price on Sep 19
$68
Fastest journey on Sep 19
10 h 40 m
Average journey duration on Sep 19
11 h 54 m
Buses on Sep 19
5
Distance
433 km
The best way to find a cheap bus ticket from La Spezia to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from La Spezia to Lyon will cost around $68 if you buy it on the day, but the cheapest tickets can be found for only $61.
It's difficult to get from La Spezia to Lyon without transferring at least once.
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FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from La Spezia to Lyon among Omio's users. If you are prioritising price, take the train, with an average ticket price of $30 For those with little time, consider booking a train, which has an average total journey time of 8h 44m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a train costs an average of $30, while a bus costs an average of $104.
Distance: 269 miles (433 km)
Most popular Bus | Train | Driving |
|---|---|---|
$104 Average price | $30 Average price Cheapest | $272 Average price (fuel + tolls) |
9h 38m Average total duration 9h 8m Onboard + 30m Additional time* | 8h 44m Average total duration Fastest 8h 14m Onboard + 30m Additional time* | 6h 34m Average total duration (door-to-door) |
0.4 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from La Spezia to Lyon:
A train is $74 less than a bus for this route with tickets for a bus from La Spezia to Lyon costing on average $104.
A train is $739 less than a flight for this route with tickets for a flight from La Spezia to Lyon costing on average $769.
Other travel options to Lyon take longer:
Train takes on average 8h 14m.
Bus takes on average 9h 8m.
Tickets start at around $104 compared to roughly $272 in fuel and tolls — a saving of about $167. The journey takes 9h 8m versus 6h 34m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:30AM | Arrival Time 12:10PM | Duration 10h40 | Departure days Fri | Cheapest price $90 |
Operator FlixBus | Departure Time 03:30AM | Arrival Time 02:10PM | Duration 10h40 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $66 |
Operator FlixBus | Departure Time 07:10AM | Arrival Time 06:10PM | Duration 11h00 | Departure days Mon, Tue, Sat, Sun | Cheapest price $68 |
Operator FlixBus | Departure Time 02:00PM | Arrival Time 01:55AM | Duration 11h55 | Departure days Fri | Cheapest price $75 |
Operator FlixBus | Departure Time 03:30PM | Arrival Time 02:50AM | Duration 11h20 | Departure days Fri | Cheapest price $84 |
Operator FlixBus | Departure Time 03:35PM | Arrival Time 03:55AM | Duration 12h20 | Departure days Wed | Cheapest price $60 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 03:55AM | Duration 11h55 | Departure days Mon, Thu, Sat, Sun | Cheapest price $61 |
Operator FlixBus | Departure Time 05:30PM | Arrival Time 06:45AM | Duration 13h15 | Departure days Fri | Cheapest price $103 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 06:30AM | Duration 12h25 | Departure days Mon, Thu, Sat, Sun | Cheapest price $67 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 07:45AM | Duration 13h30 | Departure days Fri | Cheapest price $53 |
Operator FlixBus | Departure Time 07:15PM | Arrival Time 08:45AM | Duration 13h30 | Departure days Wed, Thu, Sat, Sun | Cheapest price $64 |
The table below shows live departures for La Spezia to Lyon buses for tomorrow, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 3:30 AM La Specia, Via Giosuè Carducci | 10h40 | 2:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 7:10 AM La Specia, Via Giosuè Carducci | 11h00 | 6:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 4:00 PM La Specia, Via Giosuè Carducci | 11h55 | 3:55 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 6:05 PM La Specia, Via Giosuè Carducci | 12h25 | 6:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 7:15 PM La Specia, Via Giosuè Carducci | 13h30 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer |
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from La Spezia to Lyon run on average 4 times per day, taking around 9h 8m. Cheap bus tickets for this journey start at $56 but you can travel from only $2 by train.
The earliest bus runs at 00:05, the last at 23:00. The fastest bus covers the 269 miles (433 km) distance in 8h 5m.
Distance 269 miles (433 km) |
Average bus duration 9h 8m |
Cheapest ticket price $56 |
Buses per day 4 |
Fastest bus 8h 5m |
First bus 12:05 AM |
Last bus 11:00 PM |
Cheapest Month Mar |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Wed |
Best time to book 21 days |
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from La Spezia to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most La Spezia to Lyon buses use the La Spezia, Via Giosuè Carducci to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) station pair, with some services arriving at Lyon, Gare Routière de Perrache. Use this guide to compare La Spezia and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Ticket office support is available at Lyon, St Exupéry Aéroport.
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
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