Knoxville, TN to Lafayette, LA bus

Sat, Jun 20
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Alsa
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Rede Expressos
Costa Verde
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Costa Verde
2,000+ travel companies
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Travel Information

Compare bus and flight for Knoxville, TN to Lafayette, LA

Omio recommends booking the bus as it is the most popular option from Knoxville, TN to Lafayette, LA among Omio's users. If you are prioritising price take the bus with prices starting from $203. For those with little time consider booking a flight which can get you there in 6h 3m. The ticket price range depends on the travel mode: a bus costs an average of $203, and a flight costs an average of $466.

Distance: 613 miles (987 km)

Compare bus with

Most popular
Bus
Flight
Driving

$221

Average price

Cheapest

$488

Average price

$139

Average price

(fuel + tolls)

20h 55m

Average total duration

20h 25m

Onboard

+

30m

Additional time*

9h 3m

Average total duration

Fastest

6h 3m

Onboard

+

3h 0m

Additional time*

10h 22m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Knoxville, TN to Lafayette, LA is a bus with an average price of $221 (€181).

This is compared to other travel options from Knoxville, TN to Lafayette, LA:

A bus is $267 (€218) less than a flight for this route with tickets for a flight from Knoxville, TN to Lafayette, LA costing on average $488 (€399).

The fastest way to travel from Knoxville, TN to Lafayette, LA is by flight with an average journey time of 6h 3m.

Other travel options to Lafayette, LA take longer:

Bus takes on average 20h 25m.

It's helpful to compare your options as there are 2 ways to travel between Knoxville, TN and Lafayette, LA including taking a bus and flight.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Knoxville, TN to Lafayette, LA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
07:40PM
Arrival Time
12:20PM
Duration
17h40
Departure days
Mon
Cheapest price
$131
Operator
Greyhound
Departure Time
11:40PM
Arrival Time
08:05PM
Duration
20h25
Departure days
Fri
Cheapest price
$203

Live departures

Knoxville, TN to Lafayette, LA bus times

The table below shows live departures for Knoxville, TN to Lafayette, LA buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound11:40 PM Knoxville, TN
20h25
8:05 PM Lafayette, LA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Knoxville, TN to Lafayette, LA by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Jun 20
Sun
Jun 21
Mon
Jun 22
Tue
Jun 23
Wed
Jun 24
Thu
Jun 25
Fri
Jun 26

Journey information

Overview: Bus from Knoxville, TN to Lafayette, LA

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Icon of bus

Buses from Knoxville, TN to Lafayette, LA run on average 2 times per day, taking around 20h 25m. Cheap bus tickets for this journey start at $203 (€166) if you book in advance.

The earliest bus runs at 02:00, the last at 23:50. The fastest bus covers the 613 miles (987 km) distance in 20h 25m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
613 miles (987 km)
Average bus duration
20h 25m
Cheapest ticket price
$203 (€166)
Buses per day
2
Fastest bus
20h 25m
First bus
2:00 AM
Last bus
11:50 PM
Cheapest Month
Jan
Cheapest Day
Thu
High Season
Jan - Mar
Low Season
Apr - Jun
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Knoxville, TN to Lafayette, LA

Find answers to the most common questions about traveling from Knoxville, TN to Lafayette, LA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lafayette, LA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Knoxville, TN to Lafayette, LA can start from as little as $203 (€166) when you book in advance. The average bus ticket price for Knoxville, TN to Lafayette, LA is $221 (€181) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Knoxville, TN to Lafayette, LA is 20h 25m to travel the 613 miles (987 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Knoxville, TN to Lafayette, LA leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Knoxville, TN to Lafayette, LA leaves at 11:50 PM.
A trip to Lafayette, LA from Knoxville, TN is worth doing but not as a day trip with a journey time of 20h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Knoxville, TN to Lafayette, LA is January.
It's helpful to compare your options as there are 2 ways to travel between Knoxville, TN and Lafayette, LA including taking a bus and flight.
No, there are no bathrooms on board the bus from Knoxville, TN to Lafayette, LA.
No, the bus from Knoxville, TN to Lafayette, LA has no accessibility options.
No, bikes are not allowed on board the bus from Knoxville, TN to Lafayette, LA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Knoxville, TN to Lafayette, LA.
No, luggage for the bus from Knoxville, TN to Lafayette, LA needs to be booked in addition.
No, there are no additional luggage options for the bus from Knoxville, TN to Lafayette, LA.
Unfortunately, pets are not allowed on the bus from Knoxville, TN to Lafayette, LA.
No, there are no USB plugs on board the bus from Knoxville, TN to Lafayette, LA.
No, there is no WiFi on board the bus from Knoxville, TN to Lafayette, LA.
Since neither Knoxville, TN nor Lafayette, LA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Lafayette, LA, travelers should be aware of common safety concerns such as petty theft, especially in crowded areas and parking lots. Scams involving overcharging or misleading taxi and rideshare services can occur, so it’s best to use reputable companies and confirm fares upfront. Additionally, travelers should stay alert in nightlife districts, avoid isolated areas at night, and secure personal belongings to prevent pickpocketing.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Knoxville, TN to Lafayette, LA

Knoxville
Lafayette
The major bus station for departures in Knoxville is Knoxville, Kirkwood Street. Find all the information you need to know about services, amenities and connections at Knoxville, Kirkwood Street for your trip from Knoxville to Lafayette.
Knoxville, Kirkwood Street
information

More options for your journey from Knoxville, TN to Lafayette, LA

Here are some other resources that might have the information you need

Tickets and more information for coaches to Lafayette, LA

Most popular buses to and from Lafayette, LA and Knoxville, TN

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