Knoxville, TN to Lafayette, LA bus with Greyhound

Sat, Sep 19
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The cheapest and fastest buses from Knoxville, TN to Lafayette, LA

Showing times, prices and bookable tickets for Sep 19

Cheapest price on Sep 19

$111

Average ticket price on Sep 19

$111

Fastest journey on Sep 19

17 h 20 m

Average journey duration on Sep 19

18 h 43 m

Buses on Sep 19

2

Distance

987 km

Cheap tickets

The best way to find a cheap bus ticket from Knoxville, TN to Lafayette, LA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Knoxville, TN to Lafayette, LA will cost around $111 if you buy it on the day, but the cheapest tickets can be found for only $111.

Fast buses

It's difficult to get from Knoxville, TN to Lafayette, LA without transferring at least once.

  • Greyhound · +FlixBusFlixBus
    8:00 PM20h05
    Knoxville, Kirkwood Street, TN
    3:05 PMLafayette, TA Travel center
    $1111One-way
    2 transfers
  • Greyhound ·
    8:00 PM17h20
    Knoxville, Kirkwood Street, TN
    12:20 PMLafayette, Lee Ave (Greyhound Bus Station), LA
    $1111One-way
    1 transfer

Travel Information

Compare bus for Knoxville, TN to Lafayette, LA

Omio recommends booking the bus as it is the most popular option from Knoxville, TN to Lafayette, LA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $132 For those with little time, consider booking a bus, which has an average total journey time of 16h 40m. Average ticket prices depend on the travel mode: a bus costs an average of $132, while a bus costs an average of $132.

Distance: 613 miles (987 km)

Compare bus with

Most popular
Bus
Driving

$132

Average price

Cheapest

$142

Average price

(fuel + tolls)

16h 40m

Average total duration

Fastest

16h 10m

Onboard

+

30m

Additional time*

10h 22m

Average total duration

(door-to-door)

Greyhound

Most popular bus company

Your own car or car rental

Direct Options

Direct Options

The cheapest way to travel from Knoxville, TN to Lafayette, LA is a bus with an average price of $132.
The fastest way to travel from Knoxville, TN to Lafayette, LA is by bus with an average journey time of 16h 10m.
Yes, you can take a bus between Knoxville, TN and Lafayette, LA.
We recommend using the bus as it is the most popular way to get from Knoxville, TN to Lafayette, LA among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $132 compared to roughly $142 in fuel and tolls — a saving of about $9. The journey takes 16h 10m versus 10h 22m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Knoxville, TN to Lafayette, LA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
08:00PM
Arrival Time
12:20PM
Duration
17h20
Departure days
Fri, Sat, Sun
Cheapest price
$90

Live departures

Knoxville, TN to Lafayette, LA bus times

The table below shows live departures for Knoxville, TN to Lafayette, LA buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound · 8:00 PM Knoxville, Kirkwood Street, TN
17h20
12:20 PM Lafayette, Lee Ave (Greyhound Bus Station), LA1 transfer
Greyhound · +FlixBusFlixBus8:00 PM Knoxville, Kirkwood Street, TN
20h05
3:05 PM Lafayette, TA Travel center2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Knoxville, TN to Lafayette, LA by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Sep 19
Sun
Sep 20
Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
Fri
Sep 25

Why should you book Knoxville, TN to Lafayette, LA buses with Omio?

Greyhound operates all buses services from Knoxville, TN to Lafayette, LA.
Omio is an official ticket reseller for all your travel options from Knoxville, TN to Lafayette, LA.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Journey information

Overview: Bus from Knoxville, TN to Lafayette, LA

USAUSA
USAUSA
Icon of bus

Buses from Knoxville, TN to Lafayette, LA run on average 2 times per day, taking around 16h 10m. Cheap bus tickets for this journey start at $114 if you book in advance.

The earliest bus runs at 02:00, the last at 23:50. The fastest bus covers the 613 miles (987 km) distance in 15h 40m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
613 miles (987 km)
Average bus duration
16h 10m
Cheapest ticket price
$114
Buses per day
2
Fastest bus
15h 40m
First bus
2:00 AM
Last bus
11:50 PM
Cheapest Month
Jan
Cheapest Day
Thu
High Season
Jul - Sep
Low Season
Jan - Mar
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Knoxville, TN to Lafayette, LAYou can travel by bus between Knoxville, TN to Lafayette, LA with Greyhound for as low as $114. When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
15h 40m
Cheapest Greyhound Price
$114
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Knoxville, TN to Lafayette, LA

Find answers to the most common questions about traveling from Knoxville, TN to Lafayette, LA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lafayette, LA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Knoxville, TN to Lafayette, LA can start from as little as $114 when you book in advance. The average bus ticket price for Knoxville, TN to Lafayette, LA is $132 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Knoxville, TN to Lafayette, LA is 15h 40m to travel the 613 miles (987 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Knoxville, TN to Lafayette, LA leaves at 2:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Knoxville, TN to Lafayette, LA leaves at 11:50 PM.
There are 2 buses a day from Knoxville, TN to Lafayette, LA which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Knoxville, TN to Lafayette, LA, you can count on Greyhound for the best way to get you to Lafayette, LA. You can also check all possible bus companies who offer a service between Knoxville, TN and Lafayette, LA and compare the amenities they offer before buying a bus ticket.
When departing from Knoxville, TN , you have various bus station options to start your journey from including Knoxville, Kirkwood Street, TN . When arriving in Lafayette, LA , you can end your journey in bus stations like Lafayette, TA Travel center, Lafayette, Lee Ave (Greyhound Bus Station), LA .Passengers board the bus most frequently from Knoxville, Kirkwood Street, TN, which is located around 3 miles (5 km) away from the city centre, and they get off the bus at Lafayette, TA Travel center, located 3 away from the city centre.
A trip to Lafayette, LA from Knoxville, TN is worth doing but not as a day trip with a journey time of 15h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Knoxville, TN to Lafayette, LA is January.
Yes, you can take a bus between Knoxville, TN and Lafayette, LA.
Yes, there are bathrooms on board the bus from Knoxville, TN to Lafayette, LA for bus company Greyhound.
Yes, the following accessibility options are available when taking the bus from Knoxville, TN to Lafayette, LA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Knoxville, TN to Lafayette, LA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Knoxville, TN to Lafayette, LA.
Yes, the following luggage options are included when booking a bus ticket from Knoxville, TN to Lafayette, LA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Knoxville, TN to Lafayette, LA:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Knoxville, TN to Lafayette, LA.
You can reserve your seat on the bus from Knoxville, TN to Lafayette, LA with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Knoxville, TN to Lafayette, LA with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Knoxville, TN to Lafayette, LA with the following bus company: Greyhound.
Since neither Knoxville, TN nor Lafayette, LA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Knoxville, TN to Lafayette, LA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Lafayette, LA, travelers should be aware of common safety concerns such as petty theft, especially in crowded areas and parking lots. Scams involving overcharging or misleading taxi and rideshare services can occur, so it’s best to use reputable companies and confirm fares upfront. Additionally, travelers should stay alert in nightlife districts, avoid isolated areas at night, and secure personal belongings to prevent pickpocketing.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Knoxville, TN to Lafayette, LA

Most Knoxville, TN to Lafayette, LA buses use the Knoxville, Kirkwood Street to Lafayette, Lee Ave (Greyhound Bus Station) station pair, with some services arriving at Lafayette, TA Travel center. Use this guide to compare Knoxville, TN and Lafayette, LA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Knoxville
Arrival bus stations in Lafayette

Which Knoxville, TN station do buses to Lafayette, LA leave from?

Buses from Knoxville, TN to Lafayette, LA leave from Knoxville, Kirkwood Street. The station is 3 miles (6 km) from Knoxville, TN city centre at Kirkwood St, Knoxville, TN 37914, USA.
Knoxville, Kirkwood StreetKirkwood St, Knoxville, TN 37914, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Knoxville, Kirkwood Street from Knoxville city centre

Knoxville, Kirkwood Street is 5 km from Knoxville city centre. Public transport options include:

Bus31, 33 · 20m · $2 · every ~6 min

Knoxville, Kirkwood Street bus station facilities and services

Knoxville, Kirkwood Street has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Knoxville, Kirkwood Street. ATMs are available at Knoxville, Kirkwood Street.

Tickets and information

Ticket office support is available at Knoxville, Kirkwood Street.

Parking, taxis and toilets

Available at Knoxville, Kirkwood Street: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Knoxville, Kirkwood Street: Wheelchair accessible buses available.

More options for your journey from Knoxville, TN to Lafayette, LA

Here are some other resources that might have the information you need

Tickets and more information for coaches to Lafayette, LA

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