- Must visit
Buffalo AKG Art Museum
Major regional art museum with modern, contemporary, and historic works, plus a growing campus and frequent exhibitions.
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The cheapest and fastest buses from Indianapolis, IN to Buffalo, NY
Showing times, prices and bookable tickets for Sep 15
Cheapest price on Sep 15
$81
Average ticket price on Sep 15
$82
Fastest journey on Sep 15
16 h 25 m
Average journey duration on Sep 15
17 h 52 m
Buses on Sep 15
5
Distance
699 km
Cheap tickets
The best way to find a cheap bus ticket from Indianapolis, IN to Buffalo, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Indianapolis, IN to Buffalo, NY will cost around $82 if you buy it on the day, but the cheapest tickets can be found for only $81.
Fast buses
It's difficult to get from Indianapolis, IN to Buffalo, NY without transferring at least 2 times.
FlixBus+
· 12:15 AM16h30Indianapolis, IN4:45 PMBuffalo, NFTA Metro Center$811One-way2 transfers- FlixBus+ · 1:30 PM18h30Indianapolis, IN8:00 AMBuffalo, NFTA Metro Center$811One-way2 transfers
- · · 8:10 PM20h35Indianapolis, Illinois St (Greyhound Bus Station)4:45 PMBuffalo, NFTA Metro Center$811One-way2 transfers
- FlixBus+ · 11:25 PM17h20Indianapolis, IN4:45 PMBuffalo, NFTA Metro Center$811One-way2 transfers
- · · 3:35 PM16h25Indianapolis, Illinois St (Greyhound Bus Station)8:00 AMBuffalo, NFTA Metro Center$871One-way2 transfers
- · · 3:35 PM16h25Indianapolis, Illinois St (Greyhound Bus Station)8:00 AMBuffalo, NFTA Metro Center$871One-way2 transfers
- FlixBus+ · 12:15 AM16h30Indianapolis, IN4:45 PMBuffalo, NFTA Metro Center$811One-way2 transfers
- FlixBus+ · 11:25 PM17h20Indianapolis, IN4:45 PMBuffalo, NFTA Metro Center$811One-way2 transfers
- FlixBus+ · 1:30 PM18h30Indianapolis, IN8:00 AMBuffalo, NFTA Metro Center$811One-way2 transfers
- · · 8:10 PM20h35Indianapolis, Illinois St (Greyhound Bus Station)4:45 PMBuffalo, NFTA Metro Center$811One-way2 transfers
Travel Information
Compare bus and train for Indianapolis, IN to Buffalo, NY
Omio recommends booking the bus as it is the most popular option from Indianapolis, IN to Buffalo, NY among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $114 For those with little time, consider booking a bus, which has an average total journey time of 14h 51m. Average ticket prices depend on the travel mode: a bus costs an average of $114, while a train costs an average of $400.
Distance: 434 miles (699 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$114 Average price Cheapest | $400 Average price | $103 Average price (fuel + tolls) |
14h 51m Average total duration Fastest 14h 21m Onboard + 30m Additional time* | 15h 53m Average total duration 15h 23m Onboard + 30m Additional time* | 7h 22m Average total duration (door-to-door) |
Most popular bus company |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Indianapolis, IN to Buffalo, NY is a bus with an average price of $114.
This is compared to other travel options from Indianapolis, IN to Buffalo, NY:
A bus is $286 less than a train for this route with tickets for a train from Indianapolis, IN to Buffalo, NY costing on average $400.
A bus is $456 less than a flight for this route with tickets for a flight from Indianapolis, IN to Buffalo, NY costing on average $570.
The fastest way to travel from Indianapolis, IN to Buffalo, NY is by flight with an average journey time of 3h 50m.
Other travel options to Buffalo, NY take longer:
Bus takes on average 14h 21m.
Train takes on average 15h 23m.
It's helpful to compare your options as there are 2 ways to travel between Indianapolis, IN and Buffalo, NY including taking a bus and train.
We recommend using the bus as it is the most popular way to get from Indianapolis, IN to Buffalo, NY among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $114 compared to roughly $103 in fuel and tolls — a saving of about $-10.51. The journey takes 14h 21m versus 7h 22m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Indianapolis, IN to Buffalo, NY Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:15AM | Arrival Time 04:45PM | Duration 16h30 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $80 |
Operator Greyhound | Departure Time 01:30PM | Arrival Time 08:00AM | Duration 18h30 | Departure days Everyday | Cheapest price $80 |
Operator Greyhound | Departure Time 03:35PM | Arrival Time 08:00AM | Duration 16h25 | Departure days Everyday | Cheapest price $80 |
Operator Greyhound | Departure Time 06:35PM | Arrival Time 04:45PM | Duration 22h10 | Departure days Thu | Cheapest price $96 |
Operator Greyhound | Departure Time 08:10PM | Arrival Time 04:45PM | Duration 20h35 | Departure days Everyday | Cheapest price $79 |
Operator Greyhound | Departure Time 11:25PM | Arrival Time 04:45PM | Duration 17h20 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $79 |
Live departures
Indianapolis, IN to Buffalo, NY bus times
The table below shows live departures for Indianapolis, IN to Buffalo, NY buses for today, Monday, September 14. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus+ · | 1:30 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 18h30 | 8:00 AM Buffalo, NFTA Metro Center | 2 transfers | |
| · · | 3:35 PM Indianapolis, Illinois St (Greyhound Bus Station) | 16h25 | 8:00 AM Buffalo, NFTA Metro Center | 2 transfers | |
| · · | 8:10 PM Indianapolis, Illinois St (Greyhound Bus Station) | 20h35 | 4:45 PM Buffalo, NFTA Metro Center | 2 transfers | |
| FlixBus+ · | 11:25 PM Indianapolis, E Washington St / N Delaware St (City/County Building), IN | 17h20 | 4:45 PM Buffalo, NFTA Metro Center | 2 transfers | |
| Tuesday, September 15 | |||||
| FlixBus+ · | 12:15 AM Indianapolis, IN | 16h30 | 4:45 PM Buffalo, NFTA Metro Center | 2 transfers | |
Find all the dates and times for this journey
Compare prices and tickets Indianapolis, IN to Buffalo, NY by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Indianapolis, IN to Buffalo, NY buses with Omio?
Greyhound as well as Barons Bus offer buses services from Indianapolis, IN to Buffalo, NY.
Omio is an official ticket reseller for all your travel options from Indianapolis, IN to Buffalo, NY.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of Barons Bus to find the best option for your trip from Indianapolis, IN to Buffalo, NY.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and train to ensure you get the best deal for traveling from Indianapolis, IN to Buffalo, NY.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Indianapolis, IN to Buffalo, NY.
Journey information
Overview: Bus from Indianapolis, IN to Buffalo, NY
USAUSA
Buses from Indianapolis, IN to Buffalo, NY run on average 5 times per day, taking around 14h 21m. Cheap bus tickets for this journey start at $81 if you book in advance.
The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 434 miles (699 km) distance in 13h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 434 miles (699 km) |
Average bus duration 14h 21m |
Cheapest ticket price $81 |
Buses per day 5 |
Fastest bus 13h 10m |
First bus 12:15 AM |
Last bus 11:55 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 28 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, FlixBus from Indianapolis, IN to Buffalo, NYYou can travel by bus between Indianapolis, IN to Buffalo, NY with Greyhound, FlixBus for as low as $81. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
13h 10m
Cheapest FlixBus Price
$82
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
13h 15m
Cheapest Greyhound Price
$81
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Buffalo, NY
Things to do in Buffalo, NY
Discover the best of Buffalo, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Buffalo, NY trip today.
- Recommended
Theodore Roosevelt Inaugural National Historic Site
Former presidential inaugural site with exhibits on Theodore Roosevelt, the Pan-American Exposition, and Buffalo politics.
- Recommended
Michigan Street African American Heritage Corridor
Community museum preserving Buffalo’s African American heritage through local history, culture, and rotating exhibitions.
- Must visit
Canalside
Waterfront district with canal history, public art, seasonal events, skating, and frequent family-friendly activities downtown.
- Must visit
Elmwood Village
Lively walkable neighborhood known for boutiques, galleries, architecture, and one of Buffalo’s most popular main streets.
- Must visit
Outer Harbor
Long urban trail and greenway connecting waterfront areas, parks, and neighborhoods for walking, biking, and sightseeing.
Buffalo Wings
Crisp fried chicken wings coated in spicy butter-hot sauce. Created in Buffalo, they are the city’s signature bar food and a must-try local classic.
Beef On Weck
Thin-sliced roast beef on a kummelweck roll topped with coarse salt and caraway, usually dipped in jus. It is a longtime Western New York sandwich staple.
- Gluten-free
Buffalo-Style Bean Soup
Slow-cooked bean soup with ham, tomatoes, and vegetables. It is strongly associated with Buffalo’s old taverns and Friday lunch traditions.
Oliver's Restaurant
Refined fine-dining restaurant known for seasonal New American tasting menus, polished service, and an elegant special-occasion atmosphere.
Schwabl's
Traditional German restaurant celebrated for beef on weck, sausages, and old-world charm. A Buffalo dining landmark with a cozy historic feel.
Duff's Famous Wings
Long-standing wing institution known for crispy, saucy chicken wings in a classic neighborhood bar setting with a devoted local following.
United States dollar ($)
Moderate for U.S. city travel; hotels are often cheaper than NYC, while dining and local transit stay fairly manageable for visitors.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-6 for a coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, more for great service. Taxis usually 10-15%. For cafes, round up or add $1 per drink.
FAQs: Bus from Indianapolis, IN to Buffalo, NY
Find answers to the most common questions about traveling from Indianapolis, IN to Buffalo, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Buffalo, NY, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Indianapolis, IN to Buffalo, NY can start from as little as $81 when you book in advance. The average bus ticket price for Indianapolis, IN to Buffalo, NY is $114 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Indianapolis, IN to Buffalo, NY is 13h 10m to travel the 434 miles (699 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Indianapolis, IN to Buffalo, NY leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Indianapolis, IN to Buffalo, NY leaves at 11:55 PM.
There are 5 buses a day from Indianapolis, IN to Buffalo, NY which require at least one change with Greyhound, Barons Bus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Indianapolis, IN to Buffalo, NY, you can count on Greyhound, Barons Bus for the best way to get you to Buffalo, NY. You can also check all possible bus companies who offer a service between Indianapolis, IN and Buffalo, NY and compare the amenities they offer before buying a bus ticket.
When departing from Indianapolis, IN , you have various bus station options to start your journey from including Indianapolis, Illinois St (Greyhound Bus Station) . When arriving in Buffalo, NY , you can end your journey in bus stations like Buffalo, NFTA Metro Center, Niagara Falls, Upper Rpds Rd (Rapidsview Bus Parking), ON, Niagara Falls, Table Rock Centre Station, ON, Fort Erie, 27 Municipal Centre Dr, Fort Erie, ON .Passengers board the bus most frequently from Indianapolis, Illinois St (Greyhound Bus Station), which is located around away from the city centre, and they get off the bus at Buffalo, NFTA Metro Center, located 0 away from the city centre.
A trip to Buffalo, NY from Indianapolis, IN is worth doing but not as a day trip with a journey time of 13h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Indianapolis, IN to Buffalo, NY is September.
It's helpful to compare your options as there are 2 ways to travel between Indianapolis, IN and Buffalo, NY including taking a bus and train.
Yes, the following accessibility options are available when taking the bus from Indianapolis, IN to Buffalo, NY:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Indianapolis, IN to Buffalo, NY for bus company Greyhound.
Whether you can cancel your bus ticket from Indianapolis, IN to Buffalo, NY depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Indianapolis, IN to Buffalo, NY.
Yes, the following luggage options are included when booking a bus ticket from Indianapolis, IN to Buffalo, NY:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Indianapolis, IN to Buffalo, NY:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Indianapolis, IN to Buffalo, NY.
You can reserve your seat on the bus from Indianapolis, IN to Buffalo, NY with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Indianapolis, IN to Buffalo, NY with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Indianapolis, IN to Buffalo, NY with the following bus company: Greyhound.
Since neither Indianapolis, IN nor Buffalo, NY are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Indianapolis, IN to Buffalo, NY among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Buffalo, NY, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and tourist spots. Scams involving overcharging for taxi or rideshare services have been reported, so it's advised to use licensed transportation and confirm fares beforehand. Additionally, travelers should stay aware of their surroundings at night, particularly in less populated neighborhoods, to avoid potential safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Indianapolis, IN to Buffalo, NY
Most Indianapolis, IN to Buffalo, NY buses use the Indianapolis, Illinois St (Greyhound Bus Station) to Buffalo, NFTA Metro Center station pair. Use this guide to compare Indianapolis, IN and Buffalo, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Indianapolis
Arrival bus stations in Buffalo
Which Indianapolis, IN station do buses to Buffalo, NY leave from?
Buses from Indianapolis, IN to Buffalo, NY leave from Indianapolis, Illinois St (Greyhound Bus Station). The station is 0 miles (1 km) from Indianapolis, IN city centre at 350 S Illinois St, Indianapolis, IN 46225, USA.
Indianapolis, Illinois St (Greyhound Bus Station)350 S Illinois St, Indianapolis, IN 46225, USA
City-centre transport
Getting to Indianapolis, Illinois St (Greyhound Bus Station) from Indianapolis city centre
TRUE
Indianapolis, Illinois St (Greyhound Bus Station) bus station facilities and services
Indianapolis, Illinois St (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Fast food outlets are available.
Wi-Fi and ATMs
Free Wi-Fi is available throughout the station. ATMs are aTM is located near the entrance.
Tickets and information
Ticket office support is available at Indianapolis, Illinois St (Greyhound Bus Station).
Parking, taxis and toilets
Available at Indianapolis, Illinois St (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Indianapolis, Illinois St (Greyhound Bus Station): The station is wheelchair accessible.
Which Buffalo, NY station do buses from Indianapolis, IN arrive at?
Buses from Indianapolis, IN to Buffalo, NY most often arrive at Buffalo, NFTA Metro Center. Some services arrive at Niagara Falls, Upper Rpds Rd (Rapidsview Bus Parking), so check your ticket before travel to confirm your Buffalo, NY arrival station.
Buffalo, NFTA Metro CenterBuffalo, NY, USA
City-centre transport
Getting to Buffalo, NFTA Metro Center from Buffalo city centre
TRUE
Buffalo, NFTA Metro Center bus station facilities and services
Buffalo, NFTA Metro Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free WiFi is available in the station. ATMs are aTM services are available near the entrance.
Tickets and information
Ticket office support is available at Buffalo, NFTA Metro Center.
Parking, taxis and toilets
Available at Buffalo, NFTA Metro Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Buffalo, NFTA Metro Center: Accessible for passengers with reduced mobility.
Most popular bus connections from Indianapolis, IN
More options for your journey from Indianapolis, IN to Buffalo, NY
Here are some other resources that might have the information you need
Most popular buses to and from Buffalo, NY and Indianapolis, IN
Most popular bus connections to Buffalo, NY
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