- Must visit
National Museum of Civil War Medicine
Interactive museum explaining battlefield medicine, surgery, and care during the Civil War in a historic downtown building.
Cheapest price on Oct 28
Kč 2,412
Average ticket price on Oct 28
Kč 2,412
Fastest journey on Oct 28
7 h 50 m
Average journey duration on Oct 28
7 h 50 m
Buses on Oct 28
1
Distance
106 km
The best way to find a cheap bus ticket from Harrisburg, PA to Frederick, MD is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Frederick, MD will cost around Kč 2,412 if you buy it on the day, but the cheapest tickets can be found for only Kč 2,412.
It's difficult to get from Harrisburg, PA to Frederick, MD without transferring at least once.


Buses from Harrisburg, PA to Frederick, MD run on average 2 times per day, taking around 5h 49m. Cheap bus tickets for this journey start at Kč 557 if you book in advance.
The earliest bus runs at 03:05, the last at 11:30. The fastest bus covers the 65 miles (106 km) distance in 4h 50m.
Distance 65 miles (106 km) |
Average bus duration 5h 49m |
Cheapest ticket price Kč 557 |
Buses per day 2 |
Fastest bus 4h 50m |
First bus 3:05 AM |
Last bus 11:30 AM |
Cheapest Month Jul |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Oct - Dec |
Best time to book 21 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Harrisburg, PA to Frederick, MD.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 12:30PM | Arrival Time 08:20PM | Duration 7h50 | Departure days Mon, Tue, Wed, Thu, Sun | Cheapest price Kč 2,412 |
Operator Greyhound | Departure Time 04:30PM | Arrival Time 11:25PM | Duration 6h55 | Departure days Fri, Sat | Cheapest price Kč 1,352 |
Operator Greyhound | Departure Time 05:30PM | Arrival Time 12:25AM | Duration 6h55 | Departure days Sat | Cheapest price Kč 847 |
The table below shows live departures for Harrisburg, PA to Frederick, MD buses for tomorrow, Wednesday, October 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:30 PM Harrisburg, PA | 7h50 | 8:20 PM Frederick, MD | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Frederick, MD — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frederick, MD trip today.
Interactive museum explaining battlefield medicine, surgery, and care during the Civil War in a historic downtown building.
Regional history museum with exhibits on Frederick County life, culture, and changing communities inside a restored historic home.
Contemporary art space in downtown Frederick presenting rotating exhibitions by regional and national artists in a modern gallery setting.
Linear downtown park and promenade with fountains, public art, bridges, and event spaces, ideal for walking day or evening.
Central historic district with preserved architecture, local shops, galleries, and easy access to many of Frederick’s main sights.
Popular downtown street lined with historic buildings, boutiques, public art, and one of the city’s best pedestrian atmospheres.
Maryland crab cakes are packed with blue crab and light seasoning. They are a regional staple near Frederick and widely served across Central Maryland.
Cream of crab soup is a rich Maryland favorite made with crab meat, cream, and seasoning. It reflects the state's strong Chesapeake seafood tradition.
Smith Island cake is Maryland's official state dessert, with many thin cake layers and frosting. It is a classic sweet treat found around Frederick.
Well-known farm brewery outside downtown with estate beer, pizza, and scenic grounds suited to relaxed afternoons.
Contemporary American restaurant known for wood-fired dishes, cocktails, and a polished but relaxed downtown atmosphere.
Casual local favorite for New York-style pizza, pasta, and Italian-American comfort food in the historic district.
Moderate for a U.S. mid-size city: hotels and dining are below major metros, but car-based transport and limited transit can raise visitor costs.
Tip 18-20% at restaurants, more for excellent service. Taxis usually 10-15%. Cafes often have tip jars; $1-2 is common.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Frederick, MD.
Find answers to the most common questions about traveling from Harrisburg, PA to Frederick, MD by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frederick, MD, this guide helps you travel smarter and with confidence.

Most Harrisburg, PA to Frederick, MD buses use the Harrisburg, Market St (Bus Station) to Frederick, East Street (Transit Center) station pair. Use this guide to compare Harrisburg, PA and Frederick, MD bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Ticket office support is available at Harrisburg, Market St (Bus Station).
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Frederick, East Street (Transit Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Frederick, East Street (Transit Center). ATMs are available at Frederick, East Street (Transit Center).
Ticket office support is available at Frederick, East Street (Transit Center).
Available at Frederick, East Street (Transit Center): Parking, Taxis, WC.
Accessibility facilities are available at Frederick, East Street (Transit Center): Wheelchair accessible entry and exit points.
Check bus stations information for Harrisburg, PA and Frederick, MD, including where buses depart and arrive on this route.
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