- Must visit
Delaware Art Museum
Leading Delaware art museum with American illustration, Pre-Raphaelite works, sculpture gardens, and a scenic setting above Brandywine Creek.
The best way to find a cheap bus ticket from Harrisburg, PA to Wilmington, NC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Wilmington, NC will cost around $137 if you buy it on the day, but the cheapest tickets can be found for only $137.
On Wed, Nov 04, we found 1 buses from Harrisburg, PA to Wilmington, NC, including 1 direct services.
On Wed, Nov 04 the direct buses cover the 679 km distance in an average of 18 h 35 m but if you time it right, some buses will get you there in just 18 h 35 m .
On Wed, Nov 04 the slowest buses will take 18 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Harrisburg, PA to Wilmington, NC run on average 3 times per day, taking around 14h 28m. Cheap bus tickets for this journey start at $75 if you book in advance.
The earliest bus runs at 05:00, the last at 23:20. The fastest bus covers the 421 miles (679 km) distance in 13h 15m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Harrisburg, PA to Wilmington, NC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:20AM | Arrival Time 11:05AM | Duration 31h45 | Departure days Mon, Wed, Sat | Cheapest price $132 |
Operator Greyhound | Departure Time 03:55PM | Arrival Time 08:50AM | Duration 16h55 | Departure days Mon | Cheapest price $106 |
Operator Greyhound | Departure Time 04:30PM | Arrival Time 11:05AM | Duration 18h35 | Departure days Wed, Thu, Sat, Sun | Cheapest price $97 |
Operator Greyhound | Departure Time 05:30PM | Arrival Time 02:25PM | Duration 20h55 | Departure days Mon | Cheapest price $104 |
Operator Greyhound | Departure Time 06:50PM | Arrival Time 06:55PM | Duration 24h05 | Departure days Thu, Fri, Sat, Sun | Cheapest price $111 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 06:55PM | Duration 21h25 | Departure days Tue, Sat | Cheapest price $88 |
Operator Greyhound | Departure Time 11:30PM | Arrival Time 05:50PM | Duration 18h20 | Departure days Mon | Cheapest price $103 |
The table below shows live departures for Harrisburg, PA to Wilmington, NC buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:30 PM Harrisburg, PA | 21h25 | 6:55 PM Wilmington, NC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Harrisburg, PA to Wilmington, NC with Greyhound. Overnight buses available on this route with Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Wilmington, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Wilmington, NC trip today.
Leading Delaware art museum with American illustration, Pre-Raphaelite works, sculpture gardens, and a scenic setting above Brandywine Creek.
Historic prison turned museum interpreting crime, punishment, and justice in Delaware through preserved cells and guided tours.
Hands-on children's museum on the Riverfront with interactive science, math, and creativity exhibits designed for families and younger visitors.
Redeveloped waterfront district with river walks, parks, public art, and easy access to museums, dining, and seasonal events.
Major civic square framed by historic buildings, offices, and hotels, often used for public events and a good starting point downtown.
Large urban park with formal gardens, open lawns, trails, sports areas, and frequent community events near downtown neighborhoods.
Carolina-style pulled pork barbecue, slow-smoked and chopped or shredded, is a regional staple near Wilmington, often served with vinegar-forward sauce and slaw.
Fresh local shrimp lightly breaded and fried is a classic Cape Fear coast plate, reflecting Wilmington’s strong seafood tradition and nearby fisheries.
Stone-ground grits topped with local shrimp in a rich savory sauce are widely eaten in coastal North Carolina and common on Wilmington menus.
Refined downtown restaurant serving contemporary American plates with seafood, steaks, and polished service in a historic building.
Upscale riverfront dining focused on seafood and Southern-inspired dishes, with broad water views and a polished yet relaxed feel.
Popular casual spot for Carolina barbecue, brisket, ribs, and Southern sides with a relaxed neighborhood atmosphere.
Moderate for a US coastal city. Hotels and dining are mid-priced, while public transit is limited, so visitors often spend more on car travel or rideshares.
Tip 15-20% at restaurants, $1-2 per bag for hotel staff, and 10-15% for taxis. Small tips are appreciated at cafes, but not always expected.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Wilmington, NC.
Find answers to the most common questions about traveling from Harrisburg, PA to Wilmington, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Wilmington, NC, this guide helps you travel smarter and with confidence.

Most Harrisburg, PA to Wilmington, NC buses use the Harrisburg, Market St (Bus Station) to Wilmington, Forden Station station pair. Use this guide to compare Harrisburg, PA and Wilmington, NC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Ticket office support is available at Harrisburg, Market St (Bus Station).
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Wilmington, Forden Station is 7 km from Wilmington city centre. Public transport options include:
Wilmington, Forden Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Wilmington, Forden Station. ATMs are available at Wilmington, Forden Station.
Ticket office support is available at Wilmington, Forden Station.
Available at Wilmington, Forden Station: Parking, Taxis, WC.
Accessibility facilities are available at Wilmington, Forden Station: Station is accessible for people with reduced mobility.
Check bus stations information for Harrisburg, PA and Wilmington, NC, including where buses depart and arrive on this route.