Travel Information
Compare bus, train, and flight for Harrisburg, PA to Chicago, IL
Omio recommends booking the train as it is the most popular option from Harrisburg, PA to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from $97. For those with little time consider booking a flight which can get you there in 3h 41m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a bus costs an average of $97, and a flight costs an average of $249.
Distance: 571 miles (919 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$183 Average price | $153 Average price Cheapest | $367 Average price |
16h 16m Average total duration 15h 46m Onboard + 30m Additional time* | 17h 0m Average total duration 16h 30m Onboard + 30m Additional time* | 6h 41m Average total duration Fastest 3h 41m Onboard + 3h 0m Additional time* |
0.3 - 0.8kg CO2 emissions Lowest | 0.9 - 2.3kg CO2 emissions | 2.8 - 5.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Harrisburg, PA to Chicago, IL
How to get from Harrisburg, PA to Chicago, IL by train, bus or flight.
Our recommendation
The best way to travel from Harrisburg, PA to Chicago, IL is by taking a bus because it’s the best combination of price and speed.
7:40 PM16h30Harrisburg, PA12:10 PMChicago, IL$1291One-way0 transfers
Cheapest
7:40 PM16h30Harrisburg, PA12:10 PMChicago, IL$1291One-way0 transfers
Fastest
7:40 PM16h30Harrisburg, PA12:10 PMChicago, IL$1291One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Harrisburg, PA to Chicago, IL
Travel to Chicago, IL easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Harrisburg, PA to Chicago, IL.

This is compared to other travel options from Harrisburg, PA to Chicago, IL:
A bus is $40 (€32) less than a train for this route with tickets for a train from Harrisburg, PA to Chicago, IL costing on average $137 (€109).
A bus is $152 (€121) less than a flight for this route with tickets for a flight from Harrisburg, PA to Chicago, IL costing on average $249 (€198).
Other travel options to Chicago, IL take longer:
Train takes on average 19h 9m.
Bus takes on average 14h 45m.
- Around 25 flights per day.
- Around 6 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Harrisburg, PA and Chicago, IL as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Harrisburg International Airport and arrive in O'Hare International Airport.
- Trains mostly depart from Harrisburg Station, Harrisburg, PA and arrive in Chicago Union Station, Chicago, IL.
- Buses mostly depart from Harrisburg, Market St (Bus Station), PA and arrive in Chicago, Greyhound Bus Station.
- Travel with Amtrak to go to Chicago, IL by train.
- Travel with Greyhound, FlixBus to go to Chicago, IL by bus.
- Travel with American Airlines to go to Chicago, IL by flight.
- 1 direct buses per day with FlixBus.
Travelling from Harrisburg, PA to Chicago, IL: related information
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