- Must visit
Brewery Museum
Historic museum in a preserved medieval malt house explaining beer production and everyday life in old Plzeň.
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The cheapest and fastest buses from Frankfurt am Main to Plzeň
Showing times and prices for Jun 21
Cheapest price
$37
Average price
$45
Fastest journey
7 h
Average duration
7 h 23 m
Buses per day
4
Distance
338 km
Cheap tickets
The best way to find a cheap bus ticket from Frankfurt am Main to Plzeň is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Plzeň will cost around $45 if you buy it on the day, but the cheapest tickets can be found for only $37.
Fast buses
Of the 4 buses that leave Frankfurt am Main for Plzeň on Sun, Jun 21, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 338 km distance in an average of 7 h 23 m but if you time it right, some buses will get you there in just 7 h .
On Sun, Jun 21 the slowest buses will take 7 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
8:40 AM7h00Frankfurt am Main3:40 PMPlzeň$371One-way0 transfers- 4:05 AM7h45Frankfurt am Main11:50 AMPlzeň$461One-way0 transfers
- 9:40 AM7h00Frankfurt am Main4:40 PMPlzeň$471One-way0 transfers
- 5:05 AM7h45Frankfurt am Main12:50 PMPlzeň$491One-way0 transfers
- 9:40 AM7h00Frankfurt am Main4:40 PMPlzeň$471One-way0 transfers
- 8:40 AM7h00Frankfurt am Main3:40 PMPlzeň$371One-way0 transfers
- 5:05 AM7h45Frankfurt am Main12:50 PMPlzeň$491One-way0 transfers
- 4:05 AM7h45Frankfurt am Main11:50 AMPlzeň$461One-way0 transfers
Travel Information
Compare train, bus, and flight for Frankfurt am Main to Plzeň
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Plzeň among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a flight which can get you there in 1h 50m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $165.
Distance: 210 miles (338 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$39 Average price Cheapest | $100 Average price | $231 Average price | $93 Average price (fuel + tolls) |
6h 23m Average total duration 5h 53m Onboard + 30m Additional time* | 6h 0m Average total duration 5h 30m Onboard + 30m Additional time* | 4h 50m Average total duration Fastest 1h 50m Onboard + 3h 0m Additional time* | 4h 35m Average total duration (door-to-door) |
0.3 - 0.8kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.0 - 2.0kg CO2 emissions | - CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Frankfurt am Main to Plzeň is a bus with an average price of $39 (€32).
This is compared to other travel options from Frankfurt am Main to Plzeň:
A bus is $61 (€50) less than a train for this route with tickets for a train from Frankfurt am Main to Plzeň costing on average $100 (€82).
A bus is $193 (€158) less than a flight for this route with tickets for a flight from Frankfurt am Main to Plzeň costing on average $231 (€189).
The fastest way to travel from Frankfurt am Main to Plzeň is by flight with an average journey time of 1h 50m.
Other travel options to Plzeň take longer:
Train takes on average 5h 30m.
Bus takes on average 5h 53m.
It's helpful to compare your options as there are 3 ways to travel between Frankfurt am Main and Plzeň including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Frankfurt am Main to Plzeň among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $39 (€32) compared to roughly $93 (€76) in fuel and tolls — a saving of about $55 (€45). The journey takes 5h 53m versus 4h 35m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Frankfurt am Main to Plzeň Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:05AM | Arrival Time 11:50AM | Duration 7h45 | Departure days Sun | Cheapest price $46 |
Operator FlixBus | Departure Time 04:35AM | Arrival Time 01:50PM | Duration 9h15 | Departure days Mon, Fri | Cheapest price $40 |
Operator FlixBus | Departure Time 05:05AM | Arrival Time 12:50PM | Duration 7h45 | Departure days Sun | Cheapest price $49 |
Operator FlixBus | Departure Time 06:05AM | Arrival Time 01:50PM | Duration 7h45 | Departure days Mon, Fri | Cheapest price $37 |
Operator FlixBus | Departure Time 08:40AM | Arrival Time 03:40PM | Duration 7h00 | Departure days Tue, Wed, Thu, Sun | Cheapest price $29 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 04:40PM | Duration 7h00 | Departure days Tue, Wed, Thu, Sun | Cheapest price $33 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 05:40PM | Duration 7h00 | Departure days Mon, Fri, Sat | Cheapest price $29 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 05:40PM | Duration 6h25 | Departure days Mon, Fri, Sat | Cheapest price $35 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 04:00AM | Duration 9h30 | Departure days Thu | Cheapest price $108 |
Operator FlixBus | Departure Time 07:15PM | Arrival Time 03:30AM | Duration 8h15 | Departure days Thu | Cheapest price $34 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 04:00AM | Duration 8h00 | Departure days Thu | Cheapest price $46 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 08:00AM | Duration 11h45 | Departure days Mon, Wed, Fri, Sat | Cheapest price $36 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 06:00AM | Duration 9h25 | Departure days Mon, Fri, Sat | Cheapest price $40 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 06:00AM | Duration 8h00 | Departure days Mon, Fri, Sat | Cheapest price $36 |
Operator RegioJet a.s. | Departure Time 10:30PM | Arrival Time 03:25AM | Duration 4h55 | Departure days Mon, Fri, Sat | Cheapest price $43 |
Live departures
Frankfurt am Main to Plzeň bus times
The table below shows live departures for Frankfurt am Main to Plzeň buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus | 10:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 7h00 | 5:40 PM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
| FlixBus | 11:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h25 | 5:40 PM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
| FlixBus · FlixBus | 8:15 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 9h15 | 5:30 AM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
| FlixBus · FlixBus | 8:35 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 9h25 | 6:00 AM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
| FlixBus · FlixBus | 10:00 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 8h00 | 6:00 AM Plzeň, Centrální Autobusové Nádraží | 1 transfer | |
 (Amsterdam -> Prague) | 10:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 4h55 | 3:25 AM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Frankfurt am Main to Plzeň by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sun
Jun 21
Jun 21
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Jun 22
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Jun 23
Jun 23
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Jun 24
Jun 24
Thu
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Sat
Jun 27
Jun 27
Why should you book Frankfurt am Main to Plzeň buses with Omio?
FlixBus operates all buses services from Frankfurt am Main to Plzeň.
Omio is an official ticket reseller for all your travel options from Frankfurt am Main to Plzeň.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Frankfurt am Main to Plzeň.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Frankfurt am Main to Plzeň.
Journey information
Overview: Bus from Frankfurt am Main to Plzeň
Germany
Czechia
Buses from Frankfurt am Main to Plzeň run on average 8 times per day, taking around 5h 53m. Cheap bus tickets for this journey start at $24 (€20) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:20, the last at 23:55. The fastest bus covers the 210 miles (338 km) distance in 4h 55m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 210 miles (338 km) |
Average bus duration 5h 53m |
Cheapest ticket price $24 (€20) |
Buses per day 8 |
Direct buses 3 |
Fastest bus 4h 55m |
First bus 12:20 AM |
Last bus 11:55 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Wed |
Best time to book 42 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus from Frankfurt am Main to PlzeňYou can travel by bus between Frankfurt am Main to Plzeň with FlixBus for as low as $24 (€20). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
6h 25m
Cheapest Price
$24 (€20)
FlixBus frequency
6 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Plzeň
Things to do in Plzeň
Discover the best of Plzeň — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Plzeň trip today.
- Recommended
West Bohemian Museum in Pilsen
Major regional museum with archaeology, applied arts, arms and local history collections in a grand Neo-Renaissance building.
- Recommended
Patton Memorial Pilsen
Museum focused on the liberation of Plzeň by the U.S. Army in 1945, with military vehicles, uniforms and wartime memorabilia.
- Must visit
Republic Square
Plzeň’s grand central square lined with historic facades, markets and major landmarks, making it the essential starting point for visitors.
- Recommended
Smetana Gardens
Elegant central park ring with mature trees, fountains and promenades, ideal for a break between old town sights.
- Recommended
Kopeckého Sady
Historic tree-lined promenade near the center, often used for strolling and city events, with easy access to key attractions.
- Vegetarian
- Vegan
Pilsner Lager
The city’s signature bottom-fermented pale lager, first brewed in Plzeň in 1842 and famous for its crisp bitterness and golden color.
Svíčková Na Smetaně
Marinated beef sirloin in a creamy root-vegetable sauce, usually served with bread dumplings and cranberry. A classic Czech celebratory dish.
Vepřo Knedlo Zelo
Roast pork with dumplings and braised cabbage, one of the best-known traditional Czech pub meals commonly found in Plzeň.
Rango
Long-established restaurant near the main square, popular for its polished setting, reliable cooking, and Central European dishes.
Lokál Pod Divadlem
Trusted Czech beer hall style venue focused on well-poured Pilsner, classic pub food, and a busy local atmosphere.
Na Spilce
Large, established brewery restaurant at the Pilsner Urquell complex, known for Czech classics, tank beer, and a lively historic setting.
Czech Koruna
Generally cheaper than Prague. Meals, beer, and local transport are good value; hotels vary by season.
Average meal costs
- Budget
- CZK 120-200 for street food or a simple lunch.
- Mid-range
- CZK 250-450 per person at a casual restaurant.
- Fine dining
- CZK 700-1,200+ per person at upscale venues.
- Coffee
- CZK 55-80 for a cappuccino or latte.
Tipping culture
About 5-10% in restaurants if service is good, often rounded up. Tip taxi fares up slightly. No tip needed for counter service.
Virtuální Plzeňská karta
Get the appOfficial public transport app
Prices
- Single ticket
- 24 CZK
- Day pass
- 80 CZK
To the city center
Plzeň, Centrální Autobusové Nádraží -> Plzeň hlavní nádraží
- Distance
- 1 km
- Travel time
- 12 min
- You can buy tickets in the official app or from ticket machines; validate paper tickets when required.
- Card payment is commonly available at ticket machines, but not always directly on every bus or tram, so buy before boarding when possible.
FAQs: Bus from Frankfurt am Main to Plzeň
Find answers to the most common questions about traveling from Frankfurt am Main to Plzeň by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Plzeň, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Frankfurt am Main to Plzeň can start from as little as $24 (€20) when you book in advance. The average bus ticket price for Frankfurt am Main to Plzeň is $39 (€32) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Frankfurt am Main to Plzeň is 4h 55m to travel the 210 miles (338 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Frankfurt am Main to Plzeň leaves at 12:20 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Frankfurt am Main to Plzeň leaves at 11:55 PM.
Yes, there are 3 direct buses a day from Frankfurt am Main to Plzeň with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Frankfurt am Main to Plzeň, you can count on FlixBus for the best way to get you to Plzeň. You can also check all possible bus companies who offer a service between Frankfurt am Main and Plzeň and compare the amenities they offer before buying a bus ticket.
A trip to Plzeň from Frankfurt am Main is worth doing but not as a day trip with a journey time of 4h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Frankfurt am Main to Plzeň is March.
It's helpful to compare your options as there are 3 ways to travel between Frankfurt am Main and Plzeň including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Frankfurt am Main to Plzeň:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Frankfurt am Main to Plzeň for bus company FlixBus.
Some of the most interesting sights to explore in Plzeň are:
- Pilsner Urquell Brewery, the birthplace of the world-famous Pilsner beer offering guided tours and tastings
- St. Bartholomew's Cathedral, a Gothic cathedral with a towering spire and panoramic city views
- Great Synagogue, one of the largest synagogues in the world featuring Moorish-Romanesque architecture
- Techmania Science Center, an interactive museum with exhibits on science and technology
- Plzeň Zoo, a family-friendly attraction with diverse animal species and botanical gardens.
The best things to do in Plzeň include:
- Plzeň Historical Underground, discover the extensive network of tunnels and cellars beneath the city on a guided tour
- Explore the vibrant Republic Square, the heart of Plzeň with its colorful buildings and lively atmosphere
- Visit the West Bohemian Museum, showcasing regional history and art collections
- Enjoy a performance at the J.K. Tyl Theatre, offering a range of plays, operas, and ballets
- Relax in Borský Park, a large green space perfect for picnics and leisurely walks.
Whether you can cancel your bus ticket from Frankfurt am Main to Plzeň depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Frankfurt am Main to Plzeň.
Yes, the following luggage options are included when booking a bus ticket from Frankfurt am Main to Plzeň:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Frankfurt am Main to Plzeň:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Frankfurt am Main to Plzeň. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Frankfurt am Main to Plzeň with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Frankfurt am Main to Plzeň with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Frankfurt am Main to Plzeň with the following bus company: FlixBus.
Since both Frankfurt am Main and Plzeň are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the train as it is the most popular way to get from Frankfurt am Main to Plzeň among Omio's users.
The currency used in Czechia is the Czech koruna (CZK). While many places accept card payments, cash is still widely used, especially in smaller shops and markets, so travelers should carry some cash but can also use cards conveniently in most urban areas.
In Plzeň, travelers should be cautious of pickpocketing, especially in crowded areas like the city center and public transportation. Common scams include overcharging by taxi drivers who do not use meters and unofficial currency exchange booths offering poor rates. Staying vigilant in busy tourist spots and using authorized services helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Frankfurt am Main to Plzeň
Frankfurt am Main
Plzeň
The major bus station for departures in Frankfurt am Main is Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof). Find all the information you need to know about services, amenities and connections at Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) for your trip from Frankfurt am Main to Plzeň.
Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
information
Amenities at bus station
Wifi
Parking
Dining
ATM
Taxis
Accessibility
WC
Ticket Officeinformation
Ticket Office Hours
- 00:00-23:59
Distance to city center
10 km
Car connection
Hugo-Eckener-RingWifi
- Free Wi-Fi
Dining
- McDonald's (in the station)
- Hausmann's (in the station).
Taxis
- Available outside the terminal at designated taxi stands
Accessibility
- Elevators, ramps, assistance
WC
- Available in the station
Public transit options for Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
- Bus: 61, 62, 77 Train: S8, S9
Frankfurt am Main, Hauptbahnhof
information
The major bus station for arrivals in Plzeň is Plzeň, Centrální Autobusové Nádraží. Find all the information you need to know about services, amenities and connections at Plzeň, Centrální Autobusové Nádraží for your trip to Plzeň from Frankfurt am Main.
Plzeň, Centrální Autobusové Nádraží
information
Plzen, Centralni Autobusove Nadrazi
information
Most popular bus connections from Frankfurt am Main
More options for your journey from Frankfurt am Main to Plzeň
Here are some other resources that might have the information you need
Most popular buses to and from Plzeň and Frankfurt am Main
Most popular bus connections to Plzeň
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