The cheapest and fastest buses from Frankfurt am Main to Plzeň
Cheapest price
$47
Average price
$69
Fastest journey
4 h 55 m
Average duration
6 h 56 m
Buses per day
6
Distance
338 km
The best way to find a cheap bus ticket from Frankfurt am Main to Plzeň is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Plzeň will cost around $69 if you buy it on the day, but the cheapest tickets can be found for only $47.
Of the 6 buses that leave Frankfurt am Main for Plzeň on Thu, Nov 06, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Nov 06 the direct buses cover the 338 km distance in an average of 6 h 56 m but if you time it right, some buses will get you there in just 4 h 55 m .
On Thu, Nov 06 the slowest buses will take 8 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
(Amsterdam -> Prague)
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
(Amsterdam -> Prague)
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBusTravel Information
Compare bus, train, and flight for Frankfurt am Main to Plzeň
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Plzeň among Omio's users. If you are prioritising price take the bus with prices starting from €20. For those with little time consider booking a flight which can get you there in 1h 0m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of €20, and a flight costs an average of €131.
Distance: 210 miles (338 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€32 Average price Cheapest | €64 Average price | €158 Average price |
6h 21m Average total duration 5h 51m Onboard + 30m Additional time* | 5h 59m Average total duration 5h 29m Onboard + 30m Additional time* | 4h 0m Average total duration Fastest 1h 0m Onboard + 3h 0m Additional time* |
0.3 - 0.8kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.0 - 2.0kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Frankfurt am Main to Plzeň Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:35AM | Arrival Time 01:50PM | Duration 9h15 | Departure days Mon, Fri, Sat | Cheapest price $44 |
Operator FlixBus | Departure Time 04:45AM | Arrival Time 01:50PM | Duration 9h05 | Departure days Mon, Fri, Sat | Cheapest price $40 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 05:40PM | Duration 7h00 | Departure days Wed, Thu, Fri, Sat | Cheapest price $28 |
Operator FlixBus | Departure Time 11:15AM | Arrival Time 05:40PM | Duration 6h25 | Departure days Wed, Thu, Fri, Sat | Cheapest price $28 |
Operator FlixBus | Departure Time 01:00PM | Arrival Time 11:50PM | Duration 10h50 | Departure days Mon | Cheapest price $40 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 01:45AM | Duration 11h00 | Departure days Mon | Cheapest price $40 |
Operator FlixBus | Departure Time 06:05PM | Arrival Time 04:30AM | Duration 10h25 | Departure days Mon | Cheapest price $43 |
Operator FlixBus | Departure Time 08:15PM | Arrival Time 04:30AM | Duration 8h15 | Departure days Mon, Thu, Fri, Sat | Cheapest price $38 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 06:05AM | Duration 9h35 | Departure days Mon, Thu, Fri, Sat | Cheapest price $43 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 09:00AM | Duration 12h25 | Departure days Mon | Cheapest price $43 |
Operator FlixBus | Departure Time 09:15PM | Arrival Time 09:00AM | Duration 11h45 | Departure days Mon | Cheapest price $38 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 06:05AM | Duration 8h05 | Departure days Thu, Fri, Sat | Cheapest price $42 |
Operator Regiojet | Departure Time 10:30PM | Arrival Time 03:25AM | Duration 4h55 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price $33 |
Live departures
Frankfurt am Main to Plzeň bus times
The table below shows live departures for Frankfurt am Main to Plzeň buses for today, Wednesday, November 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
(Amsterdam -> Prague) | 9:30 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 4h55 | 2:25 AM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
| Thursday, November 6 | |||||
FlixBus | 9:40 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 7h00 | 4:40 PM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
FlixBus | 10:15 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 6h25 | 4:40 PM Plzeň, Centrální Autobusové Nádraží | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Frankfurt am Main to Plzeň by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 06
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Nov 12
Journey information
Overview: Bus from Frankfurt am Main to Plzeň
Buses from Frankfurt am Main to Plzeň run on average 8 times per day, taking around 5h 51m. Cheap bus tickets for this journey start at $25 (€20) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:20, the last at 23:55. The fastest bus covers the 210 miles (338 km) distance in 4h 55m.
Distance 210 miles (338 km) |
Average bus duration 5h 51m |
Cheapest ticket price $25 (€20) |
Buses per day 8 |
Direct buses 3 |
Fastest bus 4h 55m |
First bus 00:20 |
Last bus 23:55 |
Bus providers: FlixBus from Frankfurt am Main to PlzeňYou can travel by bus between Frankfurt am Main to Plzeň with FlixBus for as low as $25 (€20). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Frankfurt am Main to Plzeň
Find answers to the most common questions about traveling from Frankfurt am Main to Plzeň by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Plzeň, this guide helps you travel smarter and with confidence.

Passengers board the bus most frequently from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36), which is located around 8.4 miles (13.6 km) away from the city centre, and they get off the bus at Plzeň, Centrální Autobusové Nádraží, located 1.6 miles (2.6 km) away from the city centre.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Pilsner Urquell Brewery, the birthplace of the world-famous Pilsner beer offering guided tours and tastings
- St. Bartholomew's Cathedral, a Gothic cathedral with a towering spire and panoramic city views
- Great Synagogue, one of the largest synagogues in the world featuring Moorish-Romanesque architecture
- Techmania Science Center, an interactive museum with exhibits on science and technology
- Plzeň Zoo, a family-friendly attraction with diverse animal species and botanical gardens.
- Plzeň Historical Underground, discover the extensive network of tunnels and cellars beneath the city on a guided tour
- Explore the vibrant Republic Square, the heart of Plzeň with its colorful buildings and lively atmosphere
- Visit the West Bohemian Museum, showcasing regional history and art collections
- Enjoy a performance at the J. K. Tyl Theatre, offering a range of plays, operas, and ballets
- Relax in Borský Park, a large green space perfect for picnics and leisurely walks.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Frankfurt am Main to Plzeň, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Frankfurt am Main to Plzeň
- 00:00-23:59
- Free Wi-Fi
- McDonald's (in the station)
- Hausmann's (in the station).
- Available outside the terminal at designated taxi stands.
- Elevators, ramps, assistance
- Available in the station.
- Bus: 61, 62, 77 Train: S8, S9
Most popular bus connections from Frankfurt am Main
More options for your journey from Frankfurt am Main to Plzeň
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