Travel Information
Compare train, bus, and flight for Frankfurt am Main to Plzeň
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Plzeň among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $48 For those with little time, consider booking a flight, which has an average total journey time of 4h 44m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $48, while a flight costs an average of $421.
Distance: 210 miles (338 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$79 Average price | $48 Average price Cheapest | $421 Average price | $92 Average price (fuel + tolls) |
6h 0m Average total duration 5h 30m Onboard + 30m Additional time* | 7h 15m Average total duration 6h 45m Onboard + 30m Additional time* | 4h 44m Average total duration Fastest 2h 44m Onboard + 2h 0m Additional time* | 4h 35m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.8kg CO2 emissions | 1.0 - 2.0kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Frankfurt am Main to Plzeň
Compare the available ways to get from Frankfurt am Main to Plzeň, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Frankfurt am Main to Plzeň:
A bus is $32 (€27) less than a train for this route with tickets for a train from Frankfurt am Main to Plzeň costing on average $79 (€66).
A bus is $374 (€314) less than a flight for this route with tickets for a flight from Frankfurt am Main to Plzeň costing on average $421 (€353).
Other travel options to Plzeň take longer:
Train takes on average 6h 0m.
Bus takes on average 7h 15m.
Tickets start at around $79 (€66) compared to roughly $92 (€78) in fuel and tolls — a saving of about $14 (€12). The journey takes 5h 30m versus 4h 35m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Frankfurt am Main to Plzeň
How to get from Frankfurt am Main to Plzeň by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Plzeň is by taking a bus because it’s the best combination of price and speed.
FlixBus11:15 AM 6h25 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) 5:40 PM Plzeň, Centrální Autobusové Nádraží $31 1 One-way 0 transfers
Cheapest
FlixBus11:15 AM 6h25 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) 5:40 PM Plzeň, Centrální Autobusové Nádraží $31 1 One-way 0 transfers
Fastest
(Amsterdam -> Prague)10:30 PM 4h55 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) 3:25 AM Plzeň, Centrální Autobusové Nádraží $42 1 One-way 0 transfers
Other options
FlixBus10:40 AM 7h00 Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) 5:40 PM Plzeň, Centrální Autobusové Nádraží $36 1 One-way 0 transfers
FlixBus · FlixBus8:15 PM 9h15 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) 5:30 AM Plzeň, Centrální Autobusové Nádraží $38 1 One-way 1 transfer
FlixBus · FlixBus4:50 AM 9h00 Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) 1:50 PM Plzeň, Centrální Autobusové Nádraží $59 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Frankfurt am Main to Plzeň
Travel to Plzeň easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Plzeň.

This is compared to other travel options from Frankfurt am Main to Plzeň:
A bus is $32 (€27) less than a train for this route with tickets for a train from Frankfurt am Main to Plzeň costing on average $79 (€66).
A bus is $374 (€314) less than a flight for this route with tickets for a flight from Frankfurt am Main to Plzeň costing on average $421 (€353).
Other travel options to Plzeň take longer:
Train takes on average 6h 0m.
Bus takes on average 7h 15m.
- Around 50 flights per day.
- Around 20 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Plzeň as scheduled services by train, bus, and flight can vary by season or day of the week.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Plzen hl.n..
- Buses mostly depart from Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) and arrive in Plzeň, Centrální Autobusové Nádraží.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Travel with Lufthansa, KLM, Lot Polish Airlines, Condor Flugdienst, British Airways, Austrian Airlines, Turkish Airlines, Swiss, KLM Cityhopper, Qatar Airways, Air Baltic, Air Dolomiti, Brussels Airlines, Lufthansa Cityline, Helvetic Airways, TAP Portugal, CitizenPlane, Edelweiss Air to go to Plzeň by flight.
- Travel with Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH to go to Plzeň by train.
- Travel with FlixBus to go to Plzeň by bus.
- 8 direct flights per day with Lufthansa, Condor Flugdienst, Air Dolomiti.
- 2 direct buses per day with FlixBus.
Travelling from Frankfurt am Main to Plzeň: related information
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