Travel Information
Compare train, bus, and flight for Frankfurt am Main to Plzeň
Omio recommends booking the train as it is the most popular option from Frankfurt am Main to Plzeň among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a flight which can get you there in 1h 50m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $165.
Distance: 210 miles (338 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$100 Average price | $39 Average price Cheapest | $231 Average price | $93 Average price (fuel + tolls) |
6h 0m Average total duration 5h 30m Onboard + 30m Additional time* | 6h 23m Average total duration 5h 53m Onboard + 30m Additional time* | 4h 50m Average total duration Fastest 1h 50m Onboard + 3h 0m Additional time* | 4h 35m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.8kg CO2 emissions | 1.0 - 2.0kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Frankfurt am Main to Plzeň:
A bus is $61 (€50) less than a train for this route with tickets for a train from Frankfurt am Main to Plzeň costing on average $100 (€82).
A bus is $192 (€158) less than a flight for this route with tickets for a flight from Frankfurt am Main to Plzeň costing on average $231 (€189).
Other travel options to Plzeň take longer:
Train takes on average 5h 30m.
Bus takes on average 5h 53m.
Travel optionsfrom Frankfurt am Main to Plzeň
How to get from Frankfurt am Main to Plzeň by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Plzeň is by taking a bus because it’s the best combination of price and speed.
FlixBus10:40 AM7h00Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)5:40 PMPlzeň, Centrální Autobusové Nádraží$291One-way0 transfers
Cheapest
FlixBus10:40 AM7h00Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)5:40 PMPlzeň, Centrální Autobusové Nádraží$291One-way0 transfers
Fastest
DE44117:30 PM1h00Frankfurt am Main Airport8:30 PMPrague Vaclav Havel Airport$1761One-way0 transfers
Other options
ICE 27 · 3571+
36112:02 PM6h45Frankfurt Airport long-distance station6:47 PMPlzen hl.n.$721One-way2 transfers
ICE 625 · 3573+
36112:57 PM5h50Frankfurt (Main) Hbf6:47 PMPlzen hl.n.$841One-way2 transfers
ICE 625 · 3573+
36112:41 PM6h06Frankfurt Airport long-distance station6:47 PMPlzen hl.n.$841One-way2 transfers
FlixBus11:15 AM6h25Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)5:40 PMPlzeň, Centrální Autobusové Nádraží$351One-way0 transfers
FlixBus · FlixBus10:00 PM8h00Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)6:00 AMPlzeň, Centrální Autobusové Nádraží$361One-way1 transfer
FlixBus · FlixBus8:15 PM9h15Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)5:30 AMPlzeň, Centrální Autobusové Nádraží$361One-way1 transfer
DE440910:00 AM1h00Frankfurt am Main Airport11:00 AMPrague Vaclav Havel Airport$1761One-way0 transfers
LH13949:45 AM1h00Frankfurt am Main Airport10:45 AMPrague Vaclav Havel Airport$1961One-way0 transfers
LH140210:15 PM1h00Frankfurt am Main Airport11:15 PMPrague Vaclav Havel Airport$1961One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Frankfurt am Main to Plzeň
Travel to Plzeň easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Plzeň.

This is compared to other travel options from Frankfurt am Main to Plzeň:
A bus is $61 (€50) less than a train for this route with tickets for a train from Frankfurt am Main to Plzeň costing on average $100 (€82).
A bus is $192 (€158) less than a flight for this route with tickets for a flight from Frankfurt am Main to Plzeň costing on average $231 (€189).
Other travel options to Plzeň take longer:
Train takes on average 5h 30m.
Bus takes on average 5h 53m.
- Around 45 flights per day.
- Around 13 trains per day.
- Around 8 buses per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Plzeň as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Frankfurt (Main) Hbf and arrive in Plzen hl.n..
- Buses mostly depart from Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) and arrive in Plzeň, Centrální Autobusové Nádraží.
- Travel with KLM, Lufthansa to go to Plzeň by flight.
- Travel with Deutsche Bahn, Deutsche Bahn Intercity (DB IC) to go to Plzeň by train.
- Travel with FlixBus to go to Plzeň by bus.
- 7 direct flights per day with Lufthansa.
- 3 direct buses per day with FlixBus.
Travelling from Frankfurt am Main to Plzeň: related information
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