- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price
$68
Average price
$68
Fastest journey
14 h
Average duration
15 h 20 m
Buses per day
2
Distance
505 km
The best way to find a cheap bus ticket from Enna to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Enna to Rome will cost around $68 if you buy it on the day, but the cheapest tickets can be found for only $68.
Of the 2 buses that leave Enna for Rome on Tue, Aug 04, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Aug 04 the direct buses cover the 505 km distance in an average of 15 h 20 m but if you time it right, some buses will get you there in just 14 h .
On Tue, Aug 04 the slowest buses will take 16 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Enna to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $29. For those with little time consider booking a train which can get you there in 9h 58m. The ticket price range depends on the travel mode: a bus costs an average of $29, and a train costs an average of $62.
Distance: 313 miles (505 km)
Most popular Bus | Train | Ferry | Driving |
|---|---|---|---|
$66 Average price Cheapest | $92 Average price | $68 Average price | $65 Average price (fuel + tolls) |
13h 9m Average total duration 12h 39m Onboard + 30m Additional time* | 10h 28m Average total duration Fastest 9h 58m Onboard + 30m Additional time* | 14h 55m Average total duration 13h 55m Onboard + 1h 0m Additional time* | 9h 37m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Enna to Rome:
A bus is $2 less than a ferry for this route with tickets for a ferry from Enna to Rome costing on average $68.
A bus is $26 less than a train for this route with tickets for a train from Enna to Rome costing on average $92.
Other travel options to Rome take longer:
Train takes on average 9h 58m.
Bus takes on average 12h 39m.
Ferry takes on average 13h 55m.
You'll arrive about -4h -2m sooner (12h 39m by bus vs 9h 37m by car) and save roughly $-0.50 compared to fuel and tolls ($66 vs $65). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by FlixBus, Itabus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:30AM | Arrival Time 07:30PM | Duration 14h00 | Departure days Mon, Wed, Thu, Fri | Cheapest price $83 |
Operator FlixBus | Departure Time 06:30AM | Arrival Time 08:30PM | Duration 14h00 | Departure days Tue, Wed, Thu, Fri, Sun | Cheapest price $66 |
Operator FlixBus | Departure Time 10:50AM | Arrival Time 03:35AM | Duration 16h45 | Departure days Sat | Cheapest price $100 |
Operator FlixBus | Departure Time 11:55AM | Arrival Time 04:35AM | Duration 16h40 | Departure days Mon, Tue, Sat | Cheapest price $29 |
Operator FlixBus | Departure Time 04:35PM | Arrival Time 04:50AM | Duration 12h15 | Departure days Sat | Cheapest price $73 |
Operator FlixBus | Departure Time 06:50PM | Arrival Time 10:40AM | Duration 15h50 | Departure days Wed, Fri, Sun | Cheapest price $37 |
Operator FlixBus | Departure Time 07:10PM | Arrival Time 07:30AM | Duration 12h20 | Departure days Wed | Cheapest price $44 |
The table below shows live departures for Enna to Rome buses for tomorrow, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:30 AM Enna | 14h00 | 8:30 PM Rome | 0 transfersDirect | |
![]() | 11:55 AM Enna | 16h40 | 4:35 AM Rome | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Enna to Rome run on average 5 times per day, taking around 12h 39m. Cheap bus tickets for this journey start at $29 if you book in advance.
There are 2 buses per day. The earliest bus runs at 00:45, the last at 23:55. The fastest bus covers the 313 miles (505 km) distance in 12h 15m.
Distance 313 miles (505 km) |
Average bus duration 12h 39m |
Cheapest ticket price $29 |
Buses per day 5 |
Direct buses 2 |
Fastest bus 12h 15m |
First bus 12:45 AM |
Last bus 11:55 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Tue |
Best time to book 35 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Find answers to the most common questions about traveling from Enna to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Enna to Rome buses use the Enna, Via Leonardo da Vinci (Bassa) to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Enna and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need