Durham, NC to Louisville, KY bus with Greyhound

Tue, Mar 17
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1,000+ travel companies
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The cheapest and fastest buses from Durham, NC to Louisville, KY

Showing times and prices for Mar 18

Cheapest price

$194

Average price

$194

Fastest journey

1 d 25 m

Average duration

1 d 25 m

Buses per day

1

Distance

658 km

Cheap tickets

The best way to find a cheap bus ticket from Durham, NC to Louisville, KY is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Durham, NC to Louisville, KY will cost around $194 if you buy it on the day, but the cheapest tickets can be found for only $194.

Fast buses

It's difficult to get from Durham, NC to Louisville, KY without transferring at least 3 times.

Flixbus USA
02:30AM24h25
Durham, NC
02:55AMLouisville, KY
$1941One-way
3 transfers

Travel Information

Compare bus, train, and flight for Durham, NC to Louisville, KY

Omio recommends booking the bus as it is the most popular option from Durham, NC to Louisville, KY among Omio's users. If you are prioritising price take the bus with prices starting from $201. For those with little time consider booking a flight which can get you there in 4h 54m. The ticket price range depends on the travel mode: a bus costs an average of $201, and a train costs an average of $444.

Distance: 408 miles (658 km)

Compare bus with

Most popular
Bus
Flight
Train

$201

Average price

Cheapest

$379

Average price

$444

Average price

22h 35m

Average total duration

22h 5m

Onboard

+

30m

Additional time*

7h 54m

Average total duration

Fastest

4h 54m

Onboard

+

3h 0m

Additional time*

71h 9m

Average total duration

70h 39m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

Live departures

Durham, NC to Louisville, KY bus times

The table below shows live departures for Durham, NC to Louisville, KY buses for today, Tuesday, March 17. You can also manually refresh the results below to see updated bus journeys.

Last updated at 1:48 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus2:30 AM Durham, NC
24h25
2:55 AM Louisville, KY3 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Durham, NC to Louisville, KY by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Wed
Mar 18
Thu
Mar 19
Fri
Mar 20
Sat
Mar 21
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Mar 22
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Mar 23
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Mar 24

Why should you book Durham, NC to Louisville, KY buses with Omio?

Greyhound as well as FlixBus offer buses services from Durham, NC to Louisville, KY.
Omio is an official ticket reseller for all your travel options from Durham, NC to Louisville, KY.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Durham, NC to Louisville, KY.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Durham, NC to Louisville, KY.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Durham, NC to Louisville, KY.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Durham, NC to Louisville, KY.

Journey information

Overview: Bus from Durham, NC to Louisville, KY

USAUSA
USAUSA
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Buses from Durham, NC to Louisville, KY run on average 7 times per day, taking around 22h 5m. Cheap bus tickets for this journey start at $201 (€164) if you book in advance.

The earliest bus runs at 01:35, the last at 22:55. The fastest bus covers the 408 miles (658 km) distance in 20h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
408 miles (658 km)
Average bus duration
22h 5m
Cheapest ticket price
$201 (€164)
Buses per day
7
Fastest bus
20h 35m
First bus
01:35
Last bus
22:55
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus from Durham, NC to Louisville, KYYou can travel by bus between Durham, NC to Louisville, KY with Greyhound, FlixBus for as low as $201 (€164). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
24h 35m
Cheapest Price
$357 (€291)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
20h 35m
Cheapest Price
$201 (€164)
Greyhound frequency
6 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Durham, NC to Louisville, KY

Find answers to the most common questions about traveling from Durham, NC to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Durham, NC to Louisville, KY can start from as little as $201 (€164) when you book in advance. The average bus ticket price for Durham, NC to Louisville, KY is $201 (€164) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Durham, NC to Louisville, KY is 20h 35m to travel the 408 miles (658 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Durham, NC to Louisville, KY leaves at 1:35 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Durham, NC to Louisville, KY leaves at 10:55 PM.
There are 7 buses a day from Durham, NC to Louisville, KY which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Durham, NC to Louisville, KY, you can count on Greyhound, FlixBus for the best way to get you to Louisville, KY. You can also check all possible bus companies who offer a service between Durham, NC and Louisville, KY and compare the amenities they offer before buying a bus ticket.
A trip to Louisville, KY from Durham, NC is worth doing but not as a day trip with a journey time of 20h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Durham, NC to Louisville, KY is March.
It's helpful to compare your options as there are 3 ways to travel between Durham, NC and Louisville, KY including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Durham, NC to Louisville, KY:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Durham, NC to Louisville, KY for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Durham, NC to Louisville, KY depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Durham, NC to Louisville, KY.
Yes, the following luggage options are included when booking a bus ticket from Durham, NC to Louisville, KY:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Durham, NC to Louisville, KY:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Durham, NC to Louisville, KY. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Durham, NC to Louisville, KY with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Durham, NC to Louisville, KY with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Durham, NC to Louisville, KY with the following bus company: Greyhound, FlixBus.

popular bus stations

Popular bus stations from Durham, NC to Louisville, KY

Durham
Louisville
The major bus station for departures in Durham is Durham, W Pettigrew St (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Durham, W Pettigrew St (Greyhound Bus Station) for your trip from Durham to Louisville.
Durham, W Pettigrew St (Greyhound Bus Station)
information
address
Address
Durham W Pettigrew St Bus Station,515 W Pettigrew St,27701

More options for your journey from Durham, NC to Louisville, KY

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