Durham, NC to Louisville, KY bus with FlixBus

Sat, Sep 19
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The cheapest and fastest buses from Durham, NC to Louisville, KY

Showing times, prices and bookable tickets for Sep 19

Cheapest price on Sep 19

$193

Average ticket price on Sep 19

$193

Fastest journey on Sep 19

1 d 25 m

Average journey duration on Sep 19

1 d 25 m

Buses on Sep 19

1

Distance

658 km

Cheap tickets

The best way to find a cheap bus ticket from Durham, NC to Louisville, KY is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Durham, NC to Louisville, KY will cost around $193 if you buy it on the day, but the cheapest tickets can be found for only $193.

Fast buses

It's difficult to get from Durham, NC to Louisville, KY without transferring at least 3 times.

  • Flixbus USA
    2:30 AM24h25
    Durham, NC
    2:55 AMLouisville, KY
    $1931One-way
    3 transfers

Travel Information

Compare bus, flight, and train for Durham, NC to Louisville, KY

Omio recommends booking the flight as it is the most popular option from Durham, NC to Louisville, KY among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $119 For those with little time, consider booking a flight, which has an average total journey time of 6h 5m. Average ticket prices depend on the travel mode: a bus costs an average of $119, while a flight costs an average of $499.

Distance: 408 miles (658 km)

Compare bus with

Bus
Most popular
Flight
Driving

$119

Average price

Cheapest

$499

Average price

$102

Average price

(fuel + tolls)

16h 41m

Average total duration

16h 11m

Onboard

+

30m

Additional time*

6h 5m

Average total duration

Fastest

4h 5m

Onboard

+

2h 0m

Additional time*

8h 16m

Average total duration

(door-to-door)

FlixBus

Most popular bus company

United

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Durham, NC to Louisville, KY is a bus with an average price of $119.

This is compared to other travel options from Durham, NC to Louisville, KY:

A bus is $381 less than a flight for this route with tickets for a flight from Durham, NC to Louisville, KY costing on average $499.

The fastest way to travel from Durham, NC to Louisville, KY is by flight with an average journey time of 4h 5m.

Other travel options to Louisville, KY take longer:

Bus takes on average 16h 11m.

It's helpful to compare your options as there are 3 ways to travel between Durham, NC and Louisville, KY including taking a bus, flight, and train.
We recommend using the bus as it is the most popular way to get from Durham, NC to Louisville, KY among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $119 compared to roughly $102 in fuel and tolls — a saving of about $-16.48. The journey takes 16h 11m versus 8h 16m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Durham, NC to Louisville, KY Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Flixbus USA
Departure Time
02:30AM
Arrival Time
02:55AM
Duration
24h25
Departure days
Mon, Wed, Sat
Cheapest price
$193
Operator
Greyhound
Departure Time
09:55AM
Arrival Time
06:30AM
Duration
20h35
Departure days
Tue
Cheapest price
$201

Live departures

Durham, NC to Louisville, KY bus times

The table below shows live departures for Durham, NC to Louisville, KY buses for tomorrow, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Flixbus USA2:30 AM Durham, NC
24h25
2:55 AM Louisville, KY3 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Durham, NC to Louisville, KY by bus, flight, or train

Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Sep 19
Sun
Sep 20
Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
Fri
Sep 25

Why should you book Durham, NC to Louisville, KY buses with Omio?

Greyhound as well as FlixBus offer buses services from Durham, NC to Louisville, KY.
Omio is an official ticket reseller for all your travel options from Durham, NC to Louisville, KY.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Durham, NC to Louisville, KY.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Durham, NC to Louisville, KY.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Durham, NC to Louisville, KY.
  • Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from Durham, NC to Louisville, KY.

Journey information

Overview: Bus from Durham, NC to Louisville, KY

USAUSA
USAUSA
Icon of bus

Buses from Durham, NC to Louisville, KY run on average 4 times per day, taking around 16h 11m. Cheap bus tickets for this journey start at $106 if you book in advance.

The earliest bus runs at 01:35, the last at 22:55. The fastest bus covers the 408 miles (658 km) distance in 15h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
408 miles (658 km)
Average bus duration
16h 11m
Cheapest ticket price
$106
Buses per day
4
Fastest bus
15h 35m
First bus
1:35 AM
Last bus
10:55 PM
Cheapest Month
Aug
Cheapest Day
Fri
High Season
Jul - Sep
Low Season
Apr - Jun
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Greyhound from Durham, NC to Louisville, KYYou can travel by bus between Durham, NC to Louisville, KY with FlixBus, Greyhound for as low as $106. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
15h 35m
Cheapest FlixBus Price
$106
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
16h 55m
Cheapest Greyhound Price
$106
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Durham, NC to Louisville, KY

Find answers to the most common questions about traveling from Durham, NC to Louisville, KY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Louisville, KY, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Durham, NC to Louisville, KY can start from as little as $106 when you book in advance. The average bus ticket price for Durham, NC to Louisville, KY is $119 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Durham, NC to Louisville, KY is 15h 35m to travel the 408 miles (658 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Durham, NC to Louisville, KY leaves at 1:35 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Durham, NC to Louisville, KY leaves at 10:55 PM.
There are 4 buses a day from Durham, NC to Louisville, KY which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Durham, NC to Louisville, KY, you can count on Greyhound, FlixBus for the best way to get you to Louisville, KY. You can also check all possible bus companies who offer a service between Durham, NC and Louisville, KY and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Durham Station, which is located around away from the city centre, and they get off the bus at Louisville, W Broadway (Greyhound Bus Station), KY, located 1 away from the city centre.
A trip to Louisville, KY from Durham, NC is worth doing but not as a day trip with a journey time of 15h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Durham, NC to Louisville, KY is August.
It's helpful to compare your options as there are 3 ways to travel between Durham, NC and Louisville, KY including taking a bus, flight, and train.
Yes, the following accessibility options are available when taking the bus from Durham, NC to Louisville, KY:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Durham, NC to Louisville, KY for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Durham, NC to Louisville, KY depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Durham, NC to Louisville, KY.
Yes, the following luggage options are included when booking a bus ticket from Durham, NC to Louisville, KY:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Durham, NC to Louisville, KY:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Durham, NC to Louisville, KY. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Durham, NC to Louisville, KY with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Durham, NC to Louisville, KY with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Durham, NC to Louisville, KY with the following bus company: Greyhound, FlixBus.
Since neither Durham, NC nor Louisville, KY are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Durham, NC to Louisville, KY among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Louisville, KY, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and around popular attractions. Scams involving overcharging by taxi or ride-share drivers can occur, so using reputable services and confirming fares upfront is advised. Travelers should also be aware of distracted driver risks and practice standard safety precautions at night. Staying vigilant and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Durham, NC to Louisville, KY

Most Durham, NC to Louisville, KY buses use the Durham, W Pettigrew St (Greyhound Bus Station) to Louisville, W Broadway (Greyhound Bus Station) station pair. Use this guide to compare Durham, NC and Louisville, KY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Durham
Arrival bus stations in Louisville
Durham, W Pettigrew St (Greyhound Bus Station)Durham W Pettigrew St Bus Station,515 W Pettigrew St,27701
City-centre transport

Getting to Durham, W Pettigrew St (Greyhound Bus Station) from Durham city centre

Bus2, 9, 12, 12B · 5m · $1 · every ~12 min

More options for your journey from Durham, NC to Louisville, KY

Here are some other resources that might have the information you need

Tickets and more information for coaches to Durham, NC
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