- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Omio recommends booking the flight as it is the most popular option from Cologne to Prague among Omio's users. If you are prioritising price take the flight with prices starting from $37. For those with little time consider booking a flight which can get you there in 1h 30m. The ticket price range depends on the travel mode: a flight costs an average of $37, and a bus costs an average of $62.
Distance: 374 miles (602 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
$66 Average price | $62 Average price Cheapest | $129 Average price (fuel + tolls) |
18h 45m Average total duration 18h 15m Onboard + 30m Additional time* | 4h 30m Average total duration Fastest 1h 30m Onboard + 3h 0m Additional time* | 9h 41m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Cologne to Prague:
A flight is $4 (€4) less than a bus for this route with tickets for a bus from Cologne to Prague costing on average $66 (€54).
Other travel options to Prague take longer:
Train takes on average 9h 55m.
Bus takes on average 18h 15m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:35AM | Arrival Time 10:15PM | Duration 18h40 | Departure days Tue, Wed | Cheapest price $102 |
Operator FlixBus | Departure Time 07:20AM | Arrival Time 02:50AM | Duration 19h30 | Departure days Wed | Cheapest price $119 |
Operator FlixBus | Departure Time 08:25AM | Arrival Time 05:55AM | Duration 21h30 | Departure days Wed | Cheapest price $116 |
Operator FlixBus | Departure Time 10:05AM | Arrival Time 03:15AM | Duration 17h10 | Departure days Tue, Wed | Cheapest price $95 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 07:30AM | Duration 20h50 | Departure days Tue, Wed | Cheapest price $103 |
Operator FlixBus | Departure Time 11:10AM | Arrival Time 08:55AM | Duration 21h45 | Departure days Tue, Wed | Cheapest price $92 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 08:45AM | Duration 19h50 | Departure days Tue, Wed | Cheapest price $104 |
Operator FlixBus | Departure Time 01:15PM | Arrival Time 07:00AM | Duration 17h45 | Departure days Tue, Wed | Cheapest price $103 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 09:20AM | Duration 19h40 | Departure days Tue, Wed | Cheapest price $92 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 01:30PM | Duration 21h15 | Departure days Tue | Cheapest price $97 |
Operator FlixBus | Departure Time 04:40PM | Arrival Time 11:45AM | Duration 19h05 | Departure days Fri | Cheapest price $70 |
Operator FlixBus | Departure Time 05:35PM | Arrival Time 04:10PM | Duration 22h35 | Departure days Tue, Wed | Cheapest price $92 |
Operator FlixBus | Departure Time 05:55PM | Arrival Time 09:25AM | Duration 15h30 | Departure days Wed | Cheapest price $109 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 11:30AM | Duration 17h00 | Departure days Tue, Wed | Cheapest price $103 |
Operator FlixBus | Departure Time 06:40PM | Arrival Time 01:30PM | Duration 18h50 | Departure days Tue, Wed | Cheapest price $101 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 12:45PM | Duration 17h50 | Departure days Tue | Cheapest price $102 |
Operator FlixBus | Departure Time 07:55PM | Arrival Time 01:30PM | Duration 17h35 | Departure days Tue, Wed | Cheapest price $101 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 01:55PM | Duration 16h45 | Departure days Tue, Wed | Cheapest price $103 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 04:10PM | Duration 18h45 | Departure days Tue, Wed | Cheapest price $102 |
Operator FlixBus | Departure Time 10:50PM | Arrival Time 09:10PM | Duration 22h20 | Departure days Tue, Wed | Cheapest price $106 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 08:20PM | Duration 20h50 | Departure days Tue, Wed | Cheapest price $97 |
The table below shows live departures for Cologne to Prague buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:10 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 16h45 | 1:55 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:25 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 18h45 | 4:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:25 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 20h10 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:25 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 15h55 | 1:20 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:50 PM Brescia, Autostazione | 22h20 | 9:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:50 PM Brescia, Autostazione | 20h40 | 7:30 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:50 PM Brescia, Autostazione | 20h30 | 7:20 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:30 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 20h50 | 8:20 PM Praha, Na Knížecí | 2 transfers | |
| Wednesday, July 15 | |||||
FlixBus · FlixBus · FlixBus | 3:35 AM Orio al Serio, Milan Bergamo Airport (Bus station) | 18h40 | 10:15 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 7:20 AM Brescia, Autostazione | 19h30 | 2:50 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 8:25 AM Orio al Serio, Milan Bergamo Airport (Bus station) | 21h30 | 5:55 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 8:25 AM Orio al Serio, Milan Bergamo Airport (Bus station) | 18h25 | 2:50 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:05 AM Orio al Serio, Milan Bergamo Airport (Bus station) | 17h10 | 3:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:05 AM Brescia, Autostazione | 17h10 | 3:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:05 AM Brescia, Autostazione | 19h40 | 5:45 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:05 AM Brescia, Autostazione | 21h25 | 7:30 AM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:40 AM Orio al Serio, Milan Bergamo Airport (Bus station) | 20h50 | 7:30 AM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus | 11:10 AM Brescia, Poliambulanza metro station | 16h05 | 3:15 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:10 AM Brescia, Poliambulanza metro station | 18h35 | 5:45 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:10 AM Brescia, Poliambulanza metro station | 20h20 | 7:30 AM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:10 AM Brescia, Poliambulanza metro station | 21h45 | 8:55 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 12:55 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 19h50 | 8:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:15 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 17h45 | 7:00 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:40 PM Brescia, Poliambulanza metro station | 20h55 | 10:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:40 PM Brescia, Poliambulanza metro station | 19h40 | 9:20 AM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:35 PM Brescia, Autostazione | 17h00 | 10:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 5:35 PM Brescia, Autostazione | 15h50 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:35 PM Brescia, Autostazione | 18h10 | 11:45 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:35 PM Brescia, Autostazione | 22h35 | 4:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus | 5:55 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 15h30 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:55 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 17h50 | 11:45 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:30 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 17h00 | 11:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus | 6:30 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 17h00 | 11:30 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 6:30 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 16h05 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 6:40 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 19h05 | 1:45 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 6:40 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 18h40 | 1:20 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 7:55 PM Orio al Serio, Milan Bergamo Airport (Bus station) | 17h35 | 1:30 PM Praha, ÚAN Florenc | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Cologne to Prague run on average 34 times per day, taking around 18h 15m. Cheap bus tickets for this journey start at $62 (€51) but you can travel from only $37 (€30) by flight.
The earliest bus runs at 01:00, the last at 23:50. The fastest bus covers the 374 miles (602 km) distance in 17h 25m.
Distance 374 miles (602 km) |
Average bus duration 18h 15m |
Cheapest ticket price $62 (€51) |
Buses per day 34 |
Fastest bus 17h 25m |
First bus 1:00 AM |
Last bus 11:50 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Jan - Mar |
Low Season Apr - Jun |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Cologne to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Cologne to Prague buses use the Orio al Serio, Aeroporto di Bergamo-Orio al Serio (Stazione degli autobus) to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Cologne and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
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