- Must visit
National Museum
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Omio recommends booking the bus as it is the most popular option from Cologne to Prague among Omio's users. If you are prioritising price, take the flight, with an average ticket price of zł239 For those with little time, consider booking a flight, which has an average total journey time of 3h 26m. Average ticket prices depend on the travel mode: a flight costs an average of zł239, while a bus costs an average of zł341.
Distance: 374 miles (602 km)
Most popular Bus | Flight | Driving |
|---|---|---|
zł341 Average price | zł239 Average price Cheapest | zł498 Average price (fuel + tolls) |
20h 27m Average total duration 19h 57m Onboard + 30m Additional time* | 3h 26m Average total duration Fastest 1h 26m Onboard + 2h 0m Additional time* | 9h 41m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Cologne to Prague:
A flight is zł102 less than a bus for this route with tickets for a bus from Cologne to Prague costing on average zł341.
Other travel options to Prague take longer:
Train takes on average 9h 55m.
Bus takes on average 19h 57m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:35AM | Arrival Time 10:15PM | Duration 18h40 | Departure days Tue, Fri | Cheapest price zł314 |
Operator FlixBus | Departure Time 08:25AM | Arrival Time 02:50AM | Duration 18h25 | Departure days Fri | Cheapest price zł425 |
Operator FlixBus | Departure Time 10:05AM | Arrival Time 07:10AM | Duration 21h05 | Departure days Tue | Cheapest price zł293 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 07:30AM | Duration 20h50 | Departure days Tue, Fri | Cheapest price zł386 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 07:10AM | Duration 19h10 | Departure days Fri | Cheapest price zł388 |
Operator FlixBus | Departure Time 12:55PM | Arrival Time 09:55AM | Duration 21h00 | Departure days Tue, Fri | Cheapest price zł312 |
Operator FlixBus | Departure Time 01:15PM | Arrival Time 07:00AM | Duration 17h45 | Departure days Tue, Fri | Cheapest price zł319 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 01:30PM | Duration 21h15 | Departure days Tue | Cheapest price zł324 |
Operator FlixBus | Departure Time 05:35PM | Arrival Time 09:25AM | Duration 15h50 | Departure days Tue | Cheapest price zł328 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 11:30AM | Duration 17h00 | Departure days Tue, Fri | Cheapest price zł314 |
Operator FlixBus | Departure Time 06:40PM | Arrival Time 01:20PM | Duration 18h40 | Departure days Tue, Fri | Cheapest price zł361 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 12:20PM | Duration 17h25 | Departure days Tue, Wed, Fri | Cheapest price zł235 |
Operator FlixBus | Departure Time 07:55PM | Arrival Time 12:25PM | Duration 16h30 | Departure days Tue, Fri | Cheapest price zł319 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 01:55PM | Duration 16h45 | Departure days Tue, Fri | Cheapest price zł314 |
Operator FlixBus | Departure Time 09:25PM | Arrival Time 01:20PM | Duration 15h55 | Departure days Tue, Fri | Cheapest price zł312 |
Operator FlixBus | Departure Time 10:50PM | Arrival Time 08:15PM | Duration 21h25 | Departure days Tue | Cheapest price zł289 |
Operator FlixBus | Departure Time 11:30PM | Arrival Time 08:20PM | Duration 20h50 | Departure days Tue, Fri | Cheapest price zł337 |
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Cologne to Prague run on average 36 times per day, taking around 19h 57m. Cheap bus tickets for this journey start at zł257 but you can travel from only zł92 by flight.
The earliest bus runs at 01:00, the last at 23:50. The fastest bus covers the 374 miles (602 km) distance in 16h 5m.
Distance 374 miles (602 km) |
Average bus duration 19h 57m |
Cheapest ticket price zł257 |
Buses per day 36 |
Fastest bus 16h 5m |
First bus 1:00 AM |
Last bus 11:50 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Jul - Sep |
Low Season Oct - Dec |
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Major museum of Czech history and natural sciences in a monumental Neo-Renaissance building overlooking Wenceslas Square.
Well-curated Jewish history museum across several historic sites. Important for understanding Prague's Jewish heritage and resilience.
Leading Czech art museum with medieval to modern works in a grand historic palace. Essential for fine art and decorative arts lovers.
Historic square at Prague's core, surrounded by Gothic and Baroque landmarks. A must for first-time visitors and classic city views.
Lively boulevard of Czech modern history, lined with shops and major buildings. Worth visiting for atmosphere and historic significance.
Romantic quarter of palaces, lanes, and church domes beneath Prague Castle. Ideal for wandering, photography, and quieter historic charm.
Slow-braised beef in a creamy root-vegetable sauce, usually served with bread dumplings. A classic Czech Sunday dish strongly linked to Bohemian home cooking.
Crisp roasted pork knuckle, often served with mustard, horseradish, and pickles. A hearty pub staple popular with Czech beer culture.
Roast pork with sauerkraut and dumplings. This iconic Czech combination is a cornerstone of traditional pub and family meals.
Traditional Czech restaurant and brewery by Prague Castle, praised for roast meats, dumplings, and polished historic interiors.
Upscale restaurant focused on Czech ingredients and game, with sophisticated service in an Art Nouveau municipal house setting.
Elegant Michelin-starred restaurant known for modern Czech tasting menus in a refined setting near the Vltava.
Moderate for Europe: transit is cheap, casual meals are reasonable, and hotels in the center can raise daily costs in peak season.
Service is often not included. Tip about 5-10% in restaurants, round up for cafes, and round up or add about 10% for taxis if service is good.
Official public transport app
Prague Central Train Station -> Wenceslas Square
Find answers to the most common questions about traveling from Cologne to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Most Cologne to Prague buses use the Orio al Serio, Aeroporto di Bergamo-Orio al Serio (Stazione degli autobus) to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Cologne and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Ticket office support is available at Praha, Hlavní Nádraží.
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Ticket office support is available at Praha, ÚAN Florenc.
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Free Wi-Fi. ATMs are located near the entrance.
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
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