- Must visit
USS Midway Museum
Museum aboard the historic aircraft carrier USS Midway with restored aircraft, flight deck exhibits, and audio tours on San Diego Bay.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
Travel Information
Compare bus and train for Santa Maria, CA to San Diego, CA
Omio recommends booking the train as it is the most popular option from Santa Maria, CA to San Diego, CA among Omio's users. If you are prioritising price take the train with prices starting from $63. For those with little time consider booking a bus which can get you there in 6h 50m. The ticket price range depends on the travel mode: a train costs an average of $63, and a bus costs an average of $136.
Distance: 243 miles (392 km)
Compare bus with
| Bus | Most popular Train | Driving |
|---|---|---|
$136 Average price | $81 Average price Cheapest | $57 Average price (fuel + tolls) |
7h 20m Average total duration Fastest 6h 50m Onboard + 30m Additional time* | 8h 30m Average total duration 8h 0m Onboard + 30m Additional time* | 4h 52m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Santa Maria, CA to San Diego, CA is a train with an average price of $81 (€67).
This is compared to other travel options from Santa Maria, CA to San Diego, CA:
A train is $54 (€44) less than a bus for this route with tickets for a bus from Santa Maria, CA to San Diego, CA costing on average $136 (€111).
The fastest way to travel from Santa Maria, CA to San Diego, CA is by bus with an average journey time of 6h 50m.
Other travel options to San Diego, CA take longer:
Train takes on average 8h 0m.
It's helpful to compare your options as there are 2 ways to travel between Santa Maria, CA and San Diego, CA including taking a bus and train.
We recommend using the train as it is the most popular way to get from Santa Maria, CA to San Diego, CA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Santa Maria, CA to San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Santa Maria Area Transit | Departure Time 06:15AM | Arrival Time 03:42PM | Duration 9h27 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $0.00 |
Operator Santa Maria Area Transit | Departure Time 08:15AM | Arrival Time 06:12PM | Duration 9h57 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $0.00 |
Operator Santa Maria Area Transit | Departure Time 10:15AM | Arrival Time 10:15PM | Duration 12h00 | Departure days Tue, Wed, Thu, Fri | Cheapest price $136 |
Operator Santa Maria Area Transit | Departure Time 01:15PM | Arrival Time 07:32AM | Duration 18h17 | Departure days Tue, Wed, Thu | Cheapest price $0.00 |
Operator Santa Maria Area Transit | Departure Time 05:00PM | Arrival Time 10:05AM | Duration 17h05 | Departure days Tue, Wed, Thu, Fri | Cheapest price $0.00 |
Compare prices and tickets Santa Maria, CA to San Diego, CA by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sun
Jun 21
Jun 21
Mon
Jun 22
Jun 22
Tue
Jun 23
Jun 23
Wed
Jun 24
Jun 24
Thu
Jun 25
Jun 25
Fri
Jun 26
Jun 26
Sat
Jun 27
Jun 27
Journey information
Overview: Bus from Santa Maria, CA to San Diego, CA
USAUSA
Buses from Santa Maria, CA to San Diego, CA run on average 6 times per day, taking around 6h 50m. Cheap bus tickets for this journey start at $136 (€111) but you can travel from only $63 (€52) by train.
The earliest bus runs at 04:01, the last at 21:25. The fastest bus covers the 243 miles (392 km) distance in 9h 27m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $63 (€52)
Distance 243 miles (392 km) |
Average bus duration 6h 50m |
Cheapest ticket price $136 (€111) |
Buses per day 6 |
Fastest bus 9h 27m |
First bus 4:01 AM |
Last bus 9:25 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Best time to book 3 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $63 (€52)
Bus providers: Santa Maria Area Transit from Santa Maria, CA to San Diego, CAYou can travel by bus between Santa Maria, CA to San Diego, CA with Santa Maria Area Transit for as low as $63 (€52). When you search for schedules and tickets, Omio will show you the best journey
Santa Maria Area Transit
Luggage & cancellation policy
Average Duration
9h 27m
Cheapest Price
$136 (€111)
Santa Maria Area Transit frequency
4 a day
Complete guide to San Diego
Things to do in San Diego
Discover the best of San Diego — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego trip today.
- Recommended
San Diego Museum of Art
Balboa Park art museum known for Spanish old masters, South Asian works, and rotating exhibitions in a landmark building.
- Recommended
Museum of Contemporary Art San Diego
Leading contemporary art museum with major postwar and current works, especially strong in Southern California and Pacific Rim artists.
- Must visit
Balboa Park
Vast cultural park with gardens, museums, Spanish Colonial Revival architecture, walking paths, and some of San Diego's best photo spots.
- Must visit
La Jolla Cove
Scenic cove known for sea lions, clear water, coastal cliffs, and highly shareable sunset and ocean-view walks.
- Must visit
Coronado Beach
Wide sandy beach beside the Hotel del Coronado, popular for walking, photography, and classic Southern California scenery.
- Gluten-free
Fish Tacos
Beer-battered or grilled local fish in tortillas, usually topped with cabbage, crema, and salsa. A signature coastal San Diego staple with strong Baja influence.
California Burrito
A San Diego original burrito filled with carne asada, fries, cheese, and salsa. It is one of the city’s most iconic late-night and casual foods.
- Gluten-free
Carne Asada Fries
French fries topped with carne asada, cheese, guacamole, sour cream, and salsa. This indulgent dish is strongly associated with San Diego taco shop culture.
Mitch's Seafood
Popular waterfront seafood restaurant serving fresh local catch, fish tacos, and sandwiches in a relaxed harbor setting near the fishing fleet.
Las Cuatro Milpas
Historic, no-frills Mexican restaurant famous for house-made tortillas, rolled tacos, and comforting traditional plates. A beloved local institution with a classic atmosphere.
Hodad's
Iconic casual spot in Ocean Beach known for oversized burgers, fries, and a lively beach-town vibe. A long-standing San Diego favorite.
United States Dollar
Prices are high by U.S. standards, especially for hotels, dining, and parking near the coast and downtown.
Average meal costs
- Budget
- USD 10-18 for tacos, fast food, or casual takeout.
- Mid-range
- USD 20-40 per person at a standard sit-down restaurant.
- Fine dining
- USD 75+ per person before drinks and tax.
- Coffee
- USD 4-7 for a latte or cappuccino.
Tipping culture
Tip 18-20% at restaurants, 20%+ for great service. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and valet.
FAQs: Bus from Santa Maria, CA to San Diego, CA
Find answers to the most common questions about traveling from Santa Maria, CA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Santa Maria, CA to San Diego, CA can start from as little as $136 (€111) when you book in advance. The average bus ticket price for Santa Maria, CA to San Diego, CA is $136 (€111) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Santa Maria, CA to San Diego, CA is 9h 27m to travel the 243 miles (392 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Santa Maria, CA to San Diego, CA leaves at 4:01 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Santa Maria, CA to San Diego, CA leaves at 9:25 PM.
There are 6 buses a day from Santa Maria, CA to San Diego, CA which require at least one change with Santa Maria Area Transit. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Santa Maria, CA to San Diego, CA, you can count on Santa Maria Area Transit for the best way to get you to San Diego, CA. You can also check all possible bus companies who offer a service between Santa Maria, CA and San Diego, CA and compare the amenities they offer before buying a bus ticket.
A trip to San Diego, CA from Santa Maria, CA is worth doing but not as a day trip with a journey time of 9h 27m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Santa Maria, CA to San Diego, CA is November.
It's helpful to compare your options as there are 2 ways to travel between Santa Maria, CA and San Diego, CA including taking a bus and train.
No, the bus from Santa Maria, CA to San Diego, CA has no accessibility options.
No, there are no bathrooms on board the bus from Santa Maria, CA to San Diego, CA.
Some of the most interesting sights to explore in San Diego, CA are:
- Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
- USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
- La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
- Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
- Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
The best things to do in San Diego, CA include:
- Explore the vibrant art scene at the Museum of Contemporary Art San Diego
- enjoy a harbor cruise for stunning views of the skyline and naval ships
- hike the scenic trails at Torrey Pines State Natural Reserve
- visit the Birch Aquarium to learn about marine life and ocean conservation
- experience the thrill of a whale watching tour off the coast.
No, bikes are not allowed on board the bus from Santa Maria, CA to San Diego, CA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Santa Maria, CA to San Diego, CA.
No, luggage for the bus from Santa Maria, CA to San Diego, CA needs to be booked in addition.
No, there are no additional luggage options for the bus from Santa Maria, CA to San Diego, CA.
Unfortunately, pets are not allowed on the bus from Santa Maria, CA to San Diego, CA.
No, there are no USB plugs on board the bus from Santa Maria, CA to San Diego, CA.
No, there is no WiFi on board the bus from Santa Maria, CA to San Diego, CA.
Since neither Santa Maria, CA nor San Diego, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Santa Maria, CA to San Diego, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Diego, CA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like beaches, public transportation, and popular tourist spots such as the Gaslamp Quarter and Old Town. Common scams include overpriced parking fees and unauthorized ticket sellers near attractions. Staying aware of surroundings, securing belongings, and using official transportation services help reduce risks. Additionally, travelers should avoid isolated areas at night and be mindful of local traffic laws when using scooters or bikes.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Santa Maria, CA to San Diego, CA
Santa Maria
San Diego
The major bus station for departures in Santa Maria is Santa Maria, Nicholson Avenue / Cypress Street. Find all the information you need to know about services, amenities and connections at Santa Maria, Nicholson Avenue / Cypress Street for your trip from Santa Maria to San Diego.
Santa Maria, Nicholson Avenue / Cypress Street
information
The major bus station for arrivals in San Diego is San Diego, West Harbor Drive (The Headquarters at Seaport District). Find all the information you need to know about services, amenities and connections at San Diego, West Harbor Drive (The Headquarters at Seaport District) for your trip to San Diego from Santa Maria.
San Diego, West Harbor Drive (The Headquarters at Seaport District)
information
San Diego, San Ysidro Transit Center
information
Most popular bus connections from Santa Maria, CA
More options for your journey from Santa Maria, CA to San Diego, CA
Here are some other resources that might have the information you need
Most popular buses to and from San Diego, CA and Santa Maria, CA
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
