Santa Maria, CA to San Diego, CA bus with Clean Air Express

Fri, Dec 19
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Clean Air Express
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Alsa
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Rede Expressos
1,000+ travel companies
Clean Air Express
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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Travel Information

Compare bus and train for Santa Maria, CA to San Diego, CA

Omio recommends booking the train as it is the most popular option from Santa Maria, CA to San Diego, CA among Omio's users. If you are prioritising price take the train with prices starting from €63. For those with little time consider booking a bus which can get you there in 6h 50m. The ticket price range depends on the travel mode: a train costs an average of €63, and a bus costs an average of €70.

Distance: 243 miles (392 km)

Compare bus with

Bus
Most popular
Train

€70

Average price

€69

Average price

Cheapest

7h 20m

Average total duration

Fastest

6h 50m

Onboard

+

30m

Additional time*

8h 32m

Average total duration

8h 2m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Compare prices and tickets Santa Maria, CA to San Diego, CA by bus or train

Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Bus from Santa Maria, CA to San Diego, CA

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Buses from Santa Maria, CA to San Diego, CA run on average 6 times per day, taking around 6h 50m. Cheap bus tickets for this journey start at $87 (€70) but you can travel from only $79 (€63) by train.

The earliest bus runs at 04:01, the last at 21:25. The fastest bus covers the 243 miles (392 km) distance in 9h 15m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $79 (€63)
Distance
243 miles (392 km)
Average bus duration
6h 50m
Cheapest ticket price
$87 (€70)
Buses per day
6
Fastest bus
9h 15m
First bus
04:01
Last bus
21:25
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $79 (€63)

Bus providers: Clean Air Express from Santa Maria, CA to San Diego, CAYou can travel by bus between Santa Maria, CA to San Diego, CA with Clean Air Express for as low as $79 (€63). When you search for schedules and tickets, Omio will show you the best journey

Clean Air Express

Luggage & cancellation policy
Average Duration
55h 34m
Cheapest Price
$82 (€66)
Clean Air Express frequency
1 a day

FAQs: Bus from Santa Maria, CA to San Diego, CA

Find answers to the most common questions about traveling from Santa Maria, CA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Santa Maria, CA to San Diego, CA can start from as little as $94 (€75) when you book in advance. The average bus ticket price for Santa Maria, CA to San Diego, CA is $94 (€75); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The bus time between Santa Maria, CA and San Diego, CA is on average 55 h 34 min   for the 242 mile (391 km) long journey, but the time it takes to go from Santa Maria, CA to San Diego, CA by bus can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Santa Maria, CA to San Diego, CA leaves at 4: 40AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Santa Maria, CA to San Diego, CA leaves at 9: 25PM.
There are 6 buses a day from Santa Maria, CA to San Diego, CA which require at least one change with Clean Air Express. Schedules can vary on holidays or weekends with fewer buses.
Take the Santa Maria, CA to San Diego, CA bus with Clean Air Express. However, it's always good to check out all possible bus companies for the route from Santa Maria, CA to San Diego, CA as there might be differences in the amenities they offer.
You have options as you can travel from Santa Maria, CA to San Diego, CA 2 different ways: bus or train.
No, the bus from Santa Maria, CA to San Diego, CA has no accessibility options.
No, there are no bathrooms on board the bus from Santa Maria, CA to San Diego, CA.
Some of the most interesting sights to explore in San Diego, CA are:
  • Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
  • USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
  • La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
  • Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
  • Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
The best things to do in San Diego, CA include:
  • Explore the vibrant art scene at the Museum of Contemporary Art San Diego
  • Enjoy a harbor cruise for stunning views of the skyline and naval ships
  • Hike the scenic trails at Torrey Pines State Natural Reserve
  • Visit the Birch Aquarium to learn about marine life and ocean conservation
  • Experience the thrill of a whale watching tour off the coast.
No, bikes are not allowed on board the bus from Santa Maria, CA to San Diego, CA.

To find the cheapest bus tickets for your trip from Santa Maria, CA to San Diego, CA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Santa Maria, CA to San Diego, CA.
    No, luggage for the bus from Santa Maria, CA to San Diego, CA needs to be booked in addition.
    No, there are no additional luggage options for the bus from Santa Maria, CA to San Diego, CA.
    Unfortunately, pets are not allowed on the bus from Santa Maria, CA to San Diego, CA.
    No, there are no USB plugs on board the bus from Santa Maria, CA to San Diego, CA.
    No, there is no WiFi on board the bus from Santa Maria, CA to San Diego, CA.

    popular bus stations

    Popular bus stations from Santa Maria, CA to San Diego, CA

    Santa Maria
    San Diego
    The major bus station for departures in Santa Maria is Santa Maria, Nicholson Avenue / Cypress Street. Find all the information you need to know about services, amenities and connections at Santa Maria, Nicholson Avenue / Cypress Street for your trip from Santa Maria to San Diego.
    Santa Maria, Nicholson Avenue / Cypress Street
    information
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