- Recommended
East Tennessee History Center
Engaging museum on regional history with permanent and rotating exhibits covering people, places, and events from East Tennessee's past.
Flights from Charlotte, NC to Knoxville, TN depart on average 17 times per day, taking around 3h 24m. Cheap flight tickets for this journey start at $337 (€275) but you can travel from only $62 (€51) by bus.
There are 4 flights per day. The earliest flight runs at 05:00, the last at 23:00. The fastest flight covers the 180 miles (290 km) distance in 1h 11m. April is the cheapest month to fly.
Distance 180 miles (290 km) |
Average flight duration 3h 24m |
Cheapest ticket price $337 (€275) |
Flights per day 17 |
Direct flights 4 |
Fastest flight 1h 11m |
First flight 5:00 AM |
Last flight 11:00 PM |
Cheapest Month Apr |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Cheapest price on Sep 21
$406
Average ticket price on Sep 21
$406
Fastest journey on Sep 21
1 h 20 m
Average journey duration on Sep 21
1 h 20 m
Flights on Sep 21
1
Distance
290 km
The best way to find a cheap flight ticket from Charlotte, NC to Knoxville, TN is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Charlotte, NC to Knoxville, TN will cost around $406 if you buy it on the day, but the cheapest tickets can be found for only $406.
On Mon, Sep 21, we found 1 flights from Charlotte, NC to Knoxville, TN, including 1 direct services.
On Mon, Sep 21 the direct flights cover the 290 km distance in an average of 1 h 20 m but if you time it right, some flights will get you there in just 1 h 20 m .
On Mon, Sep 21 the longest flights will take 1 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the flight as it is the most popular option from Charlotte, NC to Knoxville, TN among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $103 For those with little time, consider booking a flight, which has an average total journey time of 5h 24m. Average ticket prices depend on the travel mode: a bus costs an average of $103, while a flight costs an average of $686.
Distance: 180 miles (290 km)
Most popular Flight | Bus | Driving |
|---|---|---|
$686 Average price | $103 Average price Cheapest | $16 Average price (fuel + tolls) |
5h 24m Average total duration Fastest 3h 24m Onboard + 2h 0m Additional time* | 9h 0m Average total duration 8h 30m Onboard + 30m Additional time* | 3h 58m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Charlotte, NC to Knoxville, TN:
A bus is $583 (€477) less than a flight for this route with tickets for a flight from Charlotte, NC to Knoxville, TN costing on average $686 (€561).
Other travel options to Knoxville, TN take longer:
Bus takes on average 8h 30m.
The table below shows live departures for Charlotte, NC to Knoxville, TN flights for today, Sunday, September 20. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:20 PM Charlotte, NC | 1h13 | 9:33 PM Knoxville, TN | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Knoxville, TN — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Knoxville, TN trip today.
Engaging museum on regional history with permanent and rotating exhibits covering people, places, and events from East Tennessee's past.
University museum featuring changing exhibitions of American and international art in a modern gallery setting near campus.
Historic house museum preserving the home of artist Adelia Armstrong Lutz, with decorative arts, local history, and period rooms.
Lively pedestrian-friendly square lined with shops, events, and public seating. It is a central gathering place and a great base for exploring downtown.
Urban park from the 1982 World's Fair with lawns, walking paths, performance spaces, and easy access to the Sunsphere and museums.
Historic warehouse district with brick streets, galleries, murals, and nightlife. It blends railroad-era character with a creative local feel.
Find answers to the most common questions about traveling from Charlotte, NC to Knoxville, TN by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Knoxville, TN, this guide helps you travel smarter and with confidence.

Most Charlotte, NC to Knoxville, TN flights use the Douglas International Airport to Knoxville airport pair. Use this guide to compare Charlotte, NC and Knoxville, TN airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Douglas International Airport is 8 km from Charlotte city centre. Public transport options include:
Douglas International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Various restaurants including fast food and sit-down options in the main terminal; top picks include Bojangles' and Starbucks
Free Wi-Fi available throughout the airport. ATMs are located throughout the terminal.
Lost and found is available at the station.
Available at Douglas International Airport: Parking, Taxis, WC.
Available at Douglas International Airport: Car Rental.
Accessibility facilities are available at Douglas International Airport: Ramps, assistance.
Nearby hotels include Hotels nearby, such as the Sheraton Charlotte Airport Hotel, within a short drive..
Knoxville is 2 km from Knoxville city centre. Public transport options include:
Knoxville has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, and Car Rental.
Food options include: Restaurants in Concourse A and B, including Ruby Tuesday and Quiznos
Free Wi-Fi available throughout the airport. ATMs are located near ticketing and baggage claim.
Lost and found is available at the station.
Available at Knoxville: Parking, Taxis, WC.
Available at Knoxville: Car Rental.
Accessibility facilities are available at Knoxville.
Nearby hotels include Hotels within walking distance, including Hilton Knoxville Airport..
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