Travel Information
Compare train, bus, and flight for Charlotte, NC to Buffalo, NY
Omio recommends booking the train as it is the most popular option from Charlotte, NC to Buffalo, NY among Omio's users. If you are prioritising price take the bus with prices starting from $145. For those with little time consider booking a flight which can get you there in 2h 54m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a bus costs an average of $145, and a flight costs an average of $329.
Distance: 539 miles (868 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$278 Average price | $197 Average price Cheapest | $431 Average price |
22h 35m Average total duration 22h 5m Onboard + 30m Additional time* | 22h 29m Average total duration 21h 59m Onboard + 30m Additional time* | 5h 54m Average total duration Fastest 2h 54m Onboard + 3h 0m Additional time* |
0.3 - 0.8kg CO2 emissions Lowest | 0.9 - 2.2kg CO2 emissions | 2.6 - 5.2kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Charlotte, NC to Buffalo, NY
How to get from Charlotte, NC to Buffalo, NY by train, bus or flight.
Our recommendation
The best way to travel from Charlotte, NC to Buffalo, NY is by taking a bus because it’s the best combination of price and speed.
6:10 AM23h15Charlotte, NC5:25 AMBuffalo, NY$1641One-way0 transfers
Cheapest
6:10 AM23h15Charlotte, NC5:25 AMBuffalo, NY$1641One-way0 transfers
Fastest
2:45 PM22h10Charlotte, NC12:55 PMBuffalo, NY$2571One-way0 transfers
Other options
11:55 AM33h20Charlotte, NC9:15 PMBuffalo, NY$1741One-way0 transfers
7:10 PM25h50Charlotte, NC9:00 PMBuffalo, NY$2101One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Charlotte, NC to Buffalo, NY
Travel to Buffalo, NY easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Charlotte, NC to Buffalo, NY.

This is compared to other travel options from Charlotte, NC to Buffalo, NY:
A bus is $39 (€31) less than a train for this route with tickets for a train from Charlotte, NC to Buffalo, NY costing on average $184 (€148).
A bus is $184 (€148) less than a flight for this route with tickets for a flight from Charlotte, NC to Buffalo, NY costing on average $329 (€265).
Other travel options to Buffalo, NY take longer:
Bus takes on average 21h 5m.
Train takes on average 32h 47m.
- Around 27 flights per day.
- Around 16 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Charlotte, NC and Buffalo, NY as scheduled services by train, bus, and flight can vary by season or day of the week.
- Buses mostly depart from Charlotte, W 4th St (Greyhound Bus Station) and arrive in Buffalo, NFTA Metro Center.
- Trains mostly depart from Charlotte Station, Charlotte, NC and arrive in Buffalo NY Exchange Street, Buffalo, NY.
- Flights mostly depart from Douglas International Airport and arrive in Buffalo Niagara International Airport.
- Travel with FlixBus, Greyhound to go to Buffalo, NY by bus.
- Travel with Amtrak to go to Buffalo, NY by train.
- Travel with American Airlines, United to go to Buffalo, NY by flight.
- 3 direct flights per day with American Airlines.
Travelling from Charlotte, NC to Buffalo, NY: related information
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