- Must visit
Vatican Museums
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and major classical and Renaissance collections. Timed entry is strongly recommended due to very high demand.
Cheapest price
$143
Average price
$147
Fastest journey
12 h 50 m
Average duration
15 h 7 m
Buses per day
3
Distance
508 km
The best way to find a cheap bus ticket from Caltanissetta to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Caltanissetta to Rome will cost around $147 if you buy it on the day, but the cheapest tickets can be found for only $143.
Of the 3 buses that leave Caltanissetta for Rome on Fri, Jun 19, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 19 the direct buses cover the 508 km distance in an average of 15 h 7 m but if you time it right, some buses will get you there in just 12 h 50 m .
On Fri, Jun 19 the slowest buses will take 17 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus
FlixBus
FlixBus
FlixBus
FlixBus
FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Caltanissetta to Rome among Omio's users. If you are prioritising price take the flight with prices starting from $42. For those with little time consider booking a flight which can get you there in 1h 24m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a flight costs an average of $42, and a train costs an average of $42.
Distance: 315 miles (508 km)
Most popular Bus | Flight | Train | Ferry |
|---|---|---|---|
$85 Average price | $42 Average price Cheapest | $100 Average price | $67 Average price |
13h 44m Average total duration 13h 14m Onboard + 30m Additional time* | 4h 24m Average total duration Fastest 1h 24m Onboard + 3h 0m Additional time* | 11h 46m Average total duration 11h 16m Onboard + 30m Additional time* | 14h 55m Average total duration 13h 55m Onboard + 1h 0m Additional time* |
0.5 - 1.3kg CO2 emissions | 1.5 - 3.0kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Caltanissetta to Rome:
A flight is $25 (€20) less than a ferry for this route with tickets for a ferry from Caltanissetta to Rome costing on average $67 (€55).
A flight is $43 (€35) less than a bus for this route with tickets for a bus from Caltanissetta to Rome costing on average $85 (€69).
A flight is $59 (€48) less than a train for this route with tickets for a train from Caltanissetta to Rome costing on average $100 (€82).
Other travel options to Rome take longer:
Train takes on average 11h 16m.
Bus takes on average 13h 14m.
Ferry takes on average 13h 55m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:50AM | Arrival Time 07:30PM | Duration 14h40 | Departure days Wed | Cheapest price $72 |
Operator FlixBus | Departure Time 05:50AM | Arrival Time 08:30PM | Duration 14h40 | Departure days Wed | Cheapest price $101 |
Operator FlixBus | Departure Time 06:50AM | Arrival Time 09:30PM | Duration 14h40 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $79 |
Operator BlaBlaCar | Departure Time 12:00PM | Arrival Time 10:40PM | Duration 10h40 | Departure days Mon | Cheapest price $58 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 09:40AM | Duration 17h40 | Departure days Wed | Cheapest price $92 |
Operator FlixBus | Departure Time 06:00PM | Arrival Time 11:50AM | Duration 17h50 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $97 |
The table below shows live departures for Caltanissetta to Rome buses for tomorrow, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 6:50 AM Caltanissetta, Via Rochester (Autostazione) | 14h40 | 9:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 6:00 PM Caltanissetta, Via Rochester (Autostazione) | 17h50 | 11:50 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 6:00 PM Caltanissetta, Via Rochester (Autostazione) | 12h50 | 6:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, ferry, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Caltanissetta to Rome run on average 4 times per day, taking around 13h 14m. Cheap bus tickets for this journey start at $36 (€29) if you book in advance.
There are 2 buses per day. The earliest bus runs at 04:47, the last at 23:55. The fastest bus covers the 315 miles (508 km) distance in 12h 50m.
Distance 315 miles (508 km) |
Average bus duration 13h 14m |
Cheapest ticket price $36 (€29) |
Buses per day 4 |
Direct buses 2 |
Fastest bus 12h 50m |
First bus 4:47 AM |
Last bus 11:55 PM |
Cheapest Month Jul |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 63 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and major classical and Renaissance collections. Timed entry is strongly recommended due to very high demand.
One of Rome’s finest art museums, known for Bernini sculptures and paintings by Caravaggio and Raphael. Advance reservation is typically required because entry is strictly timed.
The city’s historic civic museums on Capitoline Hill, featuring Roman bronzes, imperial sculpture, and art with views over the Forum.
Elegant Baroque square built on an ancient stadium, lined with fountains, palaces, and lively street life. A classic area for strolling and people-watching.
Atmospheric neighborhood of narrow lanes, ivy-covered buildings, and busy evening streets. Popular with visitors but still one of Rome’s most characteristic areas.
Famous monumental staircase linking Piazza di Spagna and Trinità dei Monti. A highly photographed landmark and social-media favorite.
A classic Roman pasta with pecorino Romano and black pepper. It is one of the city’s most iconic dishes and a benchmark of Roman cooking.
Traditional Roman pasta made with guanciale, egg yolk, pecorino Romano, and black pepper. It is famous for its rich sauce without cream.
A beloved pasta sauce of tomato, guanciale, and pecorino Romano, closely tied to Rome’s culinary identity and served with bucatini or rigatoni.
Rome’s most famous fine-dining restaurant, offering elegant tasting menus, panoramic views, and one of the city’s most prestigious dining experiences.
A historic trattoria near the Pantheon, famous for traditional Roman dishes such as gricia, amatriciana, and seasonal specialties.
A celebrated central Rome venue known for classic Roman pasta, exceptional cured meats, and a refined but lively atmosphere.
Rome is moderate by Western Europe standards: sights are affordable, but central hotels and tourist-area dining cost more.
Service is usually included or modest. Tipping is not required, but rounding up or leaving EUR 1-2 at cafes and 5-10% at restaurants for good service is appreciated.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola -> Roma Termini
Find answers to the most common questions about traveling from Caltanissetta to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

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