Travel Information
Compare bus, train, and flight for Buffalo, NY to Fort Myers, FL
Omio recommends booking the train as it is the most popular option from Buffalo, NY to Fort Myers, FL among Omio's users. If you are prioritising price take the bus with prices starting from €125. For those with little time consider booking a flight which can get you there in 3h 41m. The ticket price range depends on the travel mode: a bus costs an average of €125, and a train costs an average of €341.
Distance: 1135 miles (1828 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
€341 Average price | €254 Average price | €125 Average price Cheapest |
36h 30m Average total duration 36h 0m Onboard + 30m Additional time* | 6h 41m Average total duration Fastest 3h 41m Onboard + 3h 0m Additional time* | 40h 50m Average total duration 40h 20m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Buffalo, NY to Fort Myers, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Buffalo to Fort Myers trains with Omio?
Amtrak operates all train services from Buffalo to Fort Myers. Omio is the only official third party seller for Amtrak tickets.
Why book with Omio vs Amtrak?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Buffalo to Fort Myers.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Amtrak tickets can only be bought on Omio or Amtrak's website as Omio is the only official third party seller for Amtrak tickets. Trainline, RailEurope, and Rail.Ninja do not sell Amtrak tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Buffalo to Fort Myers.
Journey information
Overview: Train from Buffalo, NY to Fort Myers, FL
Trains from Buffalo, NY to Fort Myers, FL run on average 1 times per day, taking around 36h 0m. Cheap train tickets for this journey start at $425 (€341) but you can travel from only $156 (€125) by bus.
The earliest train runs at 03:42, the last at 07:00. The fastest train covers the 1135 miles (1828 km) distance in 38h 57m.
Distance 1135 miles (1828 km) |
Average train duration 36h 0m |
Cheapest ticket price $425 (€341) |
Trains per day 1 |
Fastest train 38h 57m |
First train 03:42 |
Last train 07:00 |
Train companies: Amtrak from Buffalo, NY to Fort Myers, FL trainsAmtrak trains will get you between Buffalo, NY and Fort Myers, FL from $156 (€125). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Buffalo, NY to Fort Myers, FL
Find answers to the most common questions about traveling from Buffalo, NY to Fort Myers, FL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Fort Myers, FL, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Buffalo, NY to Fort Myers, FL
- 6:00 AM - 11:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking lots in the vicinity.
- Pearl Street Grill & Brewery
- Liberty Hound
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $0.50
- Courtyard by Marriott Buffalo Downtown/Canalside
- Buffalo Marriott at LECOM HARBORCENTER
- The Westin Buffalo
- Located in the main hall
- Located in the main hall
- Free
- Hall 1: main entrance, ticket office, and waiting area
- Hall 2: platforms for Empire Service and Maple Leaf trains
- Bus: Several lines available
- Metro Rail: Erie Canal Harbor Station
Most popular train connections from Buffalo, NY
More options for your journey from Buffalo, NY to Fort Myers, FL
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