Travel optionsfrom Prague to Wiesbaden
How to get from Prague to Wiesbaden by train, bus or flight.
Our recommendation
The best way to travel from Prague to Wiesbaden is by taking a bus because it’s the best combination of price and speed.
(Prague -> Amsterdam)Cheapest
(Prague -> Amsterdam)Fastest
DE4410Other options
rj 382 · rj 10382 · ICE 1556 · VIA 25028
rj 178 · rj 10178 · ICE 1558 · VIA 25024
R 690 · Os 28007 · S1 · ICE 1556
(Prague -> Amsterdam)
FlixBus · FlixBus
FlixBus · FlixBus
DE4408
DE4406
LH5653Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Prague to Wiesbaden
Travel to Wiesbaden easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Wiesbaden.

This is compared to other travel options from Prague to Wiesbaden:
A bus is $5 (€4) less than a train for this route with tickets for a train from Prague to Wiesbaden costing on average $37 (€30).
A bus is $65 (€53) less than a flight for this route with tickets for a flight from Prague to Wiesbaden costing on average $98 (€79).
Other travel options to Wiesbaden take longer:
Train takes on average 7h 53m.
Flight takes on average 1h 0m.
- Around 78 flights per day.
- Around 12 trains per day.
- Around 5 buses per day.
However, we recommend checking specific travel dates for your route between Prague and Wiesbaden as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Wiesbaden Hbf.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Wiesbaden, Busbahnhof.
- Travel with Deutsche Bahn, ÖBB | Euro City (EC), ÖBB | Railjet, České dráhy to go to Wiesbaden by train.
Travelling from Prague to Wiesbaden: related information
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