Travel Information
Compare train, bus, and flight for Prague to Wiesbaden
Omio recommends booking the train as it is the most popular option from Prague to Wiesbaden among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $45 For those with little time, consider booking a bus, which has an average total journey time of 6h 21m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $45, while a train costs an average of $94.
Distance: 273 miles (440 km)
Compare train with
Most popular Train | Bus |
|---|---|
$94 Average price | $45 Average price Cheapest |
7h 58m Average total duration 7h 28m Onboard + 30m Additional time* | 6h 21m Average total duration Fastest 5h 51m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Prague to Wiesbaden
How to get from Prague to Wiesbaden by train, bus or flight.
Our recommendation
The best way to travel from Prague to Wiesbaden is by taking a bus because it’s the best combination of price and speed.
(Prague -> Amsterdam)11:00 PM6h25Praha, ÚAN Florenc5:25 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$321One-way0 transfers
Cheapest
(Prague -> Amsterdam)11:00 PM6h25Praha, ÚAN Florenc5:25 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$321One-way0 transfers
Fastest
DE441012:10 PM0h50Prague Vaclav Havel Airport1:00 PMFrankfurt am Main Airport$1671One-way0 transfers
Other options
EC 458 · ICE 699 · S86:31 PM9h13Prague hlavní nádraží3:44 AMWiesbaden Hbf$461One-way2 transfers
R 676 · Os 28015 · S1 · 165366:47 PM10h27Prague hlavní nádraží5:14 AMWiesbaden Hbf$461One-way7 transfers
R 676 · Os 28015 · S1 · 165386:47 PM14h45Prague hlavní nádraží9:32 AMWiesbaden Hbf$531One-way4 transfers
(Prague -> Amsterdam)11:00 PM6h55Praha, ÚAN Florenc5:55 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$321One-way0 transfers
FlixBus · FlixBus11:05 PM14h00Praha, ÚAN Florenc1:05 PMWiesbaden, Busbahnhof$451One-way1 transfer
FlixBus · FlixBus7:55 AM11h40Praha, Na Knížecí7:35 PMWiesbaden, Busbahnhof$471One-way1 transfer
EW77312:30 PM1h15Prague Vaclav Havel Airport1:45 PMCologne Bonn Airport$891One-way0 transfers
LH13972:30 PM1h10Prague Vaclav Havel Airport3:40 PMFrankfurt am Main Airport$971One-way0 transfers
LH139511:45 AM1h10Prague Vaclav Havel Airport12:55 PMFrankfurt am Main Airport$971One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Prague to Wiesbaden
Travel to Wiesbaden easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Wiesbaden.

This is compared to other travel options from Prague to Wiesbaden:
A bus is $50 less than a train for this route with tickets for a train from Prague to Wiesbaden costing on average $94.
A bus is $78 less than a flight for this route with tickets for a flight from Prague to Wiesbaden costing on average $123.
Other travel options to Wiesbaden take longer:
Bus takes on average 6h 21m.
Train takes on average 7h 58m.
- Around 70 flights per day.
- Around 11 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Prague and Wiesbaden as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Wiesbaden Hbf.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Wiesbaden, Busbahnhof.
- Travel with BlaBlaCar, Pražská integrovaná doprava, FlixBus to go to Wiesbaden by bus.
- Travel with Deutsche Bahn, České dráhy, České dráhy (ČD) to go to Wiesbaden by train.
- 2 direct buses per day with BlaBlaCar.
Travelling from Prague to Wiesbaden: related information
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