Travel Information
Compare train, bus, and flight for Prague to Wiesbaden
Omio recommends booking the train as it is the most popular option from Prague to Wiesbaden among Omio's users. If you are prioritising price take the bus with prices starting from $33. For those with little time consider booking a bus which can get you there in 6h 39m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $33, and a train costs an average of $63.
Distance: 273 miles (440 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$124 Average price | $48 Average price Cheapest | $118 Average price (fuel + tolls) |
8h 3m Average total duration 7h 33m Onboard + 30m Additional time* | 7h 9m Average total duration Fastest 6h 39m Onboard + 30m Additional time* | 5h 11m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | Your own car or car rental | |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Wiesbaden:
A bus is $76 (€62) less than a train for this route with tickets for a train from Prague to Wiesbaden costing on average $124 (€102).
A bus is $124 (€102) less than a flight for this route with tickets for a flight from Prague to Wiesbaden costing on average $172 (€141).
Other travel options to Wiesbaden take longer:
Bus takes on average 6h 39m.
Train takes on average 7h 33m.
Travel optionsfrom Prague to Wiesbaden
How to get from Prague to Wiesbaden by train, bus or flight.
Our recommendation
The best way to travel from Prague to Wiesbaden is by taking a bus because it’s the best combination of price and speed.
(Prague -> Amsterdam)11:00 PM6h25Praha, ÚAN Florenc5:25 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$431One-way0 transfers
Cheapest
(Prague -> Amsterdam)11:00 PM6h25Praha, ÚAN Florenc5:25 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$431One-way0 transfers
Fastest
DE441012:10 PM0h50Prague Vaclav Havel Airport1:00 PMFrankfurt am Main Airport$1671One-way0 transfers
Other options
EX 350 · 3586 · ICE 1080 · ICE 6995:35 PM10h38Prague hlavní nádraží4:13 AMWiesbaden Hbf$601One-way4 transfers
RJ 174 · IC 2446 · ICE 695+
250342:41 PM7h47Prague-Holešovice10:28 PMWiesbaden Hbf$661One-way3 transfers
RJ 174 · ICE 1552+
250362:41 PM8h47Prague-Holešovice11:28 PMWiesbaden Hbf$661One-way2 transfers
(Prague -> Amsterdam)11:00 PM6h55Praha, ÚAN Florenc5:55 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$431One-way0 transfers
FlixBus · FlixBus11:05 PM14h00Praha, ÚAN Florenc1:05 PMWiesbaden, Busbahnhof$611One-way1 transfer
FlixBus · FlixBus9:30 AM13h40Praha, ÚAN Florenc11:10 PMWiesbaden, Busbahnhof$651One-way1 transfer
LH14016:25 PM1h10Prague Vaclav Havel Airport7:35 PMFrankfurt am Main Airport$981One-way0 transfers
EW77312:30 PM1h15Prague Vaclav Havel Airport1:45 PMCologne Bonn Airport$991One-way0 transfers
LH13939:10 AM1h10Prague Vaclav Havel Airport10:20 AMFrankfurt am Main Airport$1201One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Prague to Wiesbaden
Travel to Wiesbaden easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Wiesbaden.

This is compared to other travel options from Prague to Wiesbaden:
A bus is $76 (€62) less than a train for this route with tickets for a train from Prague to Wiesbaden costing on average $124 (€102).
A bus is $124 (€102) less than a flight for this route with tickets for a flight from Prague to Wiesbaden costing on average $172 (€141).
Other travel options to Wiesbaden take longer:
Bus takes on average 6h 39m.
Train takes on average 7h 33m.
- Around 73 flights per day.
- Around 11 trains per day.
- Around 5 buses per day.
However, we recommend checking specific travel dates for your route between Prague and Wiesbaden as scheduled services by train, bus, and flight can vary by season or day of the week.
- Trains mostly depart from Prague hlavní nádraží and arrive in Wiesbaden Hbf.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Wiesbaden, Busbahnhof.
- Travel with Pražská integrovaná doprava, FlixBus to go to Wiesbaden by bus.
- Travel with Deutsche Bahn, České dráhy, České dráhy (ČD) to go to Wiesbaden by train.
Travelling from Prague to Wiesbaden: related information
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