Travel Information
Compare train, bus, and flight for Sint-Gillis to Lyon
Omio recommends booking the train as it is the most popular option from Sint-Gillis to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €52 For those with little time, consider booking a train, which has an average total journey time of 4h 21m. Average ticket prices depend on the travel mode: a bus costs an average of €52, while a flight costs an average of €397.
Distance: 351 miles (566 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
€126 Average price | €52 Average price Cheapest | €397 Average price | €164 Average price (fuel + tolls) |
4h 21m Average total duration Fastest 3h 51m Onboard + 30m Additional time* | 10h 39m Average total duration 10h 9m Onboard + 30m Additional time* | 5h 3m Average total duration 3h 3m Onboard + 2h 0m Additional time* | 7h 6m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Compare ways to travel from Sint-Gillis to Lyon
Compare the available ways to get from Sint-Gillis to Lyon, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Sint-Gillis to Lyon:
A bus is €75 less than a train for this route with tickets for a train from Sint-Gillis to Lyon costing on average €126.
A bus is €345 less than a flight for this route with tickets for a flight from Sint-Gillis to Lyon costing on average €397.
Other travel options to Lyon take longer:
Flight takes on average 5h 3m.
Bus takes on average 10h 39m.
The journey is about 3h 15m faster (3h 51m by train vs 7h 6m by car) and roughly €38 cheaper once you factor in fuel and tolls (€126 vs €164). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Sint-Gillis to Lyon
How to get from Sint-Gillis to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Sint-Gillis to Lyon is by taking a bus because it’s the best combination of price and speed.

6:20 AM 11h30 Sint-Gillis 5:50 PM Lyon €20 1 One-way 0 transfers
Cheapest

6:20 AM 11h30 Sint-Gillis 5:50 PM Lyon €20 1 One-way 0 transfers
Fastest

4:55 PM 10h10 Sint-Gillis 3:05 AM Lyon €23 1 One-way 0 transfers
Other options

5:20 AM 11h30 Sint-Gillis 4:50 PM Lyon €20 1 One-way 0 transfers
6:05 PM 10h20 Sint-Gillis 4:25 AM Lyon €36 1 One-way 0 transfers
8:55 PM 12h25 Sint-Gillis 9:20 AM Lyon €40 1 One-way 0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Sint-Gillis to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Sint-Gillis to Lyon.

This is compared to other travel options from Sint-Gillis to Lyon:
A bus is €75 less than a train for this route with tickets for a train from Sint-Gillis to Lyon costing on average €126.
A bus is €345 less than a flight for this route with tickets for a flight from Sint-Gillis to Lyon costing on average €397.
Other travel options to Lyon take longer:
Flight takes on average 5h 3m.
Bus takes on average 10h 39m.
- Around 18 buses per day.
- Around 17 flights per day.
- Around 3 trains per day.
However, we recommend checking specific travel dates for your route between Sint-Gillis and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Brussels Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Brussels-Midi and arrive in Lyon Part Dieu.
- Buses mostly depart from Brussels, Brussels South (Gare du Midi) and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with FlixBus, BlaBlaCar Bus to go to Lyon by bus.
- Travel with SNCF | TGV INOUI to go to Lyon by train.
- Travel with Lot Polish Airlines, KLM, Lufthansa, Vueling, Brussels Airlines, Air France, Air Baltic, Lufthansa Cityline, British Airways, Air Dolomiti, KLM Cityhopper, Lufthansa City Airlines to go to Lyon by flight.
- 2 direct buses per day with FlixBus.
- 3 direct trains per day with SNCF | TGV INOUI.
- 2 direct flights per day with Brussels Airlines, Air Baltic.
Travelling from Sint-Gillis to Lyon: related information
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