Travel Information
Compare train, bus, and flight for Lyon to Sint-Gillis
Omio recommends booking the train as it is the most popular option from Lyon to Sint-Gillis among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a flight which can get you there in 1h 25m. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $71.
Distance: 351 miles (566 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$138 Average price | $37 Average price Cheapest | $203 Average price | $199 Average price (fuel + tolls) |
4h 23m Average total duration 3h 53m Onboard + 30m Additional time* | 10h 37m Average total duration 10h 7m Onboard + 30m Additional time* | 4h 25m Average total duration Fastest 1h 25m Onboard + 3h 0m Additional time* | 7h 19m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lyon to Sint-Gillis:
A bus is $101 (€83) less than a train for this route with tickets for a train from Lyon to Sint-Gillis costing on average $138 (€113).
A bus is $166 (€136) less than a flight for this route with tickets for a flight from Lyon to Sint-Gillis costing on average $203 (€166).
Other travel options to Sint-Gillis take longer:
Train takes on average 3h 53m.
Bus takes on average 10h 7m.
Travel optionsfrom Lyon to Sint-Gillis
How to get from Lyon to Sint-Gillis by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Sint-Gillis is by taking a bus because it’s the best combination of price and speed.
4788 · 503276:15 AM10h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)4:30 PMBrussels, Brussels South (Gare du Midi)$591One-way1 transfer
Cheapest
4788 · 503276:15 AM10h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)4:30 PMBrussels, Brussels South (Gare du Midi)$591One-way1 transfer
Fastest
SN35881:10 PM1h25Lyon Saint Exupery Airport2:35 PMBrussels Airport$2761One-way0 transfers
Other options
FlixBus · FlixBus6:55 PM11h50Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)6:45 AMSchaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord)$621One-way1 transfer
94742 · 16571:30 AM10h30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:00 PMBrussels, Brussels South (Gare du Midi)$681One-way1 transfer
94782 · 14662:30 AM11h00Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)1:30 PMBrussels, Brussels South (Gare du Midi)$681One-way1 transfer
SN35947:05 AM1h25Lyon Saint Exupery Airport8:30 AMBrussels Airport$2761One-way0 transfers
VY1221 · VY89869:45 AM4h45Lyon Saint Exupery Airport2:30 PMBrussels Airport$2781One-way1 transfer
VY1221 · VY89829:45 AM7h40Lyon Saint Exupery Airport5:25 PMBrussels Airport$2781One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Lyon to Sint-Gillis
Travel to Sint-Gillis easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Sint-Gillis.

This is compared to other travel options from Lyon to Sint-Gillis:
A bus is $101 (€83) less than a train for this route with tickets for a train from Lyon to Sint-Gillis costing on average $138 (€113).
A bus is $166 (€136) less than a flight for this route with tickets for a flight from Lyon to Sint-Gillis costing on average $203 (€166).
Other travel options to Sint-Gillis take longer:
Train takes on average 3h 53m.
Bus takes on average 10h 7m.
- Around 21 buses per day.
- Around 13 flights per day.
- Around 4 trains per day.
However, we recommend checking specific travel dates for your route between Lyon and Sint-Gillis as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Lyon Saint Exupery Airport and arrive in Brussels Airport.
- Trains mostly depart from Lyon Part Dieu and arrive in Brussels-Midi.
- Buses mostly depart from Lyon, Perrache Bus Station and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with SNCF | TGV INOUI to go to Sint-Gillis by train.
- Travel with BlaBlaCar Bus, FlixBus to go to Sint-Gillis by bus.
- Travel with Brussels Airlines to go to Sint-Gillis by flight.
- 4 direct trains per day with SNCF | TGV INOUI.
- 3 direct buses per day with BlaBlaCar Bus, FlixBus.
- 2 direct flights per day with Brussels Airlines.
Travelling from Lyon to Sint-Gillis: related information
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