Travel Information
Compare train and bus for Mestre to Pisa
Omio recommends booking the train as it is the most popular option from Mestre to Pisa among Omio's users. If you are prioritising price take the bus with prices starting from $16. For those with little time consider booking a bus which can get you there in 4h 26m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a bus costs an average of $16, and a train costs an average of $26.
Distance: 152 miles (246 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$45 Average price | $35 Average price Cheapest | $99 Average price (fuel + tolls) |
5h 5m Average total duration 4h 35m Onboard + 30m Additional time* | 4h 56m Average total duration Fastest 4h 26m Onboard + 30m Additional time* | 3h 9m Average total duration (door-to-door) |
0.1 - 0.2kg CO2 emissions Lowest | 0.2 - 0.6kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Mestre to Pisa:
A bus is $9 (€8) less than a train for this route with tickets for a train from Mestre to Pisa costing on average $45 (€36).
Other travel options to Pisa take longer:
Train takes on average 4h 35m.
Travel optionsfrom Mestre to Pisa
How to get from Mestre to Pisa by train, bus or flight.
Our recommendation
The best way to travel from Mestre to Pisa is by taking a train because it’s the best combination of price and speed.
Regionale 16791+
Intercity 594+
Regionale Veloce 40472:58 PM4h30Venezia Mestre Ospedale7:28 PMPisa Centrale$501One-way2 transfers
Cheapest
Regionale 16791+
Intercity 594+
Regionale Veloce 40472:58 PM4h30Venezia Mestre Ospedale7:28 PMPisa Centrale$501One-way2 transfers
Fastest
8905+
Regionale Veloce 40238:17 AM3h34Venice Mestre11:51 AMPisa Centrale$801One-way1 transfer
Other options
Regionale 16775+
Intercity 584+
Regionale Veloce 404312:26 PM5h02Venezia Mestre Ospedale5:28 PMPisa Centrale$501One-way2 transfers
8915+
Regionale Veloce 40452:17 PM3h34Venice Mestre5:51 PMPisa Centrale$801One-way1 transfer
8923+
Regionale Veloce 40494:17 PM3h37Venice Mestre7:54 PMPisa Centrale$801One-way1 transfer
FlixBus · FlixBus7:15 PM5h35Venezia, Viale Stazione / Via Dante (Mestre Stazione)12:50 AMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$511One-way1 transfer
FlixBus · FlixBus6:50 PM6h00Venezia, Tronchetto Vaporetti12:50 AMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$521One-way1 transfer
FlixBus · FlixBus6:50 AM7h00Venezia, Viale Stazione / Via Dante (Mestre Stazione)1:50 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)$671One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 15
May 16
May 17
May 18
May 19
May 20
May 21
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Mestre to Pisa
Travel to Pisa easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mestre to Pisa.

This is compared to other travel options from Mestre to Pisa:
A bus is $15 (€12) less than a train for this route with tickets for a train from Mestre to Pisa costing on average $45 (€36).
Other travel options to Pisa take longer:
Train takes on average 4h 35m.
- Around 14 trains per day.
- Around 5 buses per day.
However, we recommend checking specific travel dates for your route between Mestre and Pisa as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Venezia Mestre Ospedale and arrive in Pisa Centrale.
- Buses mostly depart from Venezia, Viale Stazione / Via Dante (Mestre Stazione) and arrive in Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
- Travel with FlixBus, BlaBlaCar to go to Pisa by bus.
- Travel with Italo, Frecciarossa, Intercity, Regionale, Intercity Notte to go to Pisa by train.
- 2 direct buses per day with FlixBus, BlaBlaCar.
Travelling from Mestre to Pisa: related information
Here are some other resources that might have the information you need
