Travel Information
Compare train, bus, and flight for Mannheim to Genoa
Omio recommends booking the bus as it is the most popular option from Mannheim to Genoa among Omio's users. If you are prioritising price, take the train, with an average ticket price of €34 For those with little time, consider booking a flight, which has an average total journey time of 5h 19m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.6 - 1.4kg. Average ticket prices depend on the travel mode: a train costs an average of €34, while a flight costs an average of €448.
Distance: 352 miles (567 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
€100 Average price | €34 Average price Cheapest | €448 Average price | €182 Average price (fuel + tolls) |
13h 29m Average total duration 12h 59m Onboard + 30m Additional time* | 12h 40m Average total duration 12h 10m Onboard + 30m Additional time* | 5h 19m Average total duration Fastest 3h 19m Onboard + 2h 0m Additional time* | 8h 25m Average total duration (door-to-door) |
0.6 - 1.4kg CO2 emissions Lowest | - CO2 emissions | 1.7 - 3.4kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Mannheim to Genoa:
A train is €66 less than a bus for this route with tickets for a bus from Mannheim to Genoa costing on average €100.
A train is €414 less than a flight for this route with tickets for a flight from Mannheim to Genoa costing on average €448.
Other travel options to Genoa take longer:
Train takes on average 12h 40m.
Bus takes on average 13h 29m.
Tickets start at around €100 compared to roughly €182 in fuel and tolls — a saving of about €82. The journey takes 12h 59m versus 8h 25m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Mannheim to Genoa
How to get from Mannheim to Genoa by train, bus or flight.
Our recommendation
The best way to travel from Mannheim to Genoa is by taking a bus because it’s the best combination of price and speed.
FlixBus9:40 PM11h50Mannheim, ZOB (Heinrich-Von-Stephan-Straße)9:30 AMGenova, Via Fanti D'Italia€651One-way0 transfers
Cheapest
FlixBus9:40 PM11h50Mannheim, ZOB (Heinrich-Von-Stephan-Straße)9:30 AMGenova, Via Fanti D'Italia€651One-way0 transfers
Fastest
LH124+
LH18928:15 PM3h05Frankfurt am Main Airport11:20 PMGenoa Airport€3551One-way1 transfer
Other options
ICE 991 · RJ 1183+
Regionale TRENORD 2638 · Regionale Veloce 30776:33 AM13h45Mannheim Hbf8:18 PMGenoa Piazza Principe€1641One-way3 transfers
ICE 991 · RJ 1183+
Regionale TRENORD 2642 · Regionale Veloce 30416:33 AM15h45Mannheim Hbf10:18 PMGenoa Piazza Principe€1641One-way3 transfers
ICE 991 · RJ 1183+
Regionale TRENORD 2636+
Intercity 6796:33 AM13h11Mannheim Hbf7:44 PMGenoa Piazza Principe€1721One-way3 transfers
FlixBus · FlixBus8:30 AM13h40Mannheim, ZOB (Heinrich-Von-Stephan-Straße)10:10 PMGenova, Via Fanti D'Italia€681One-way1 transfer
FlixBus · FlixBus · FlixBus8:30 AM15h35Mannheim, ZOB (Heinrich-Von-Stephan-Straße)12:05 AMGenoa, Piazza della Vittoria€701One-way2 transfers
FlixBus · FlixBus12:35 PM16h35Mannheim, ZOB (Heinrich-Von-Stephan-Straße)5:10 AMGenova, Via Fanti D'Italia€951One-way1 transfer
VY1869 · VY60109:45 AM5h50Stuttgart Airport3:35 PMGenoa Airport€2121One-way1 transfer
AZ407 · AZ13896:25 PM4h25Frankfurt am Main Airport10:50 PMGenoa Airport€2641One-way1 transfer
ICE 2520+
AZ407 · AZ138911:33 AM11h17Mannheim Hbf10:50 PMGenoa Airport€2821One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Mannheim to Genoa
Travel to Genoa easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mannheim to Genoa.

This is compared to other travel options from Mannheim to Genoa:
A train is €66 less than a bus for this route with tickets for a bus from Mannheim to Genoa costing on average €100.
A train is €414 less than a flight for this route with tickets for a flight from Mannheim to Genoa costing on average €448.
Other travel options to Genoa take longer:
Train takes on average 12h 40m.
Bus takes on average 13h 29m.
- Around 34 flights per day.
- Around 5 buses per day.
- Around 3 trains per day.
However, we recommend checking specific travel dates for your route between Mannheim and Genoa as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Genoa Airport.
- Trains mostly depart from Mannheim Hbf and arrive in Genoa Piazza Principe.
- Buses mostly depart from Mannheim, ZOB (Heinrich-Von-Stephan-Straße) and arrive in Genova, Via Fanti D'Italia.
- Travel with FlixBus, BlaBlaCar Bus to go to Genoa by bus.
- Travel with Deutsche Bahn, Deutsche Bahn Intercity (DB IC), Nederlandse Spoorwegen (NS) to go to Genoa by train.
- Travel with Air Dolomiti to go to Genoa by flight.
- 1 direct buses per day with FlixBus, BlaBlaCar Bus.
Travelling from Mannheim to Genoa: related information
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