Travel Information
Compare bus, train, and flight for Lugano to Brussels
Omio recommends booking the bus as it is the most popular option from Lugano to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $105 For those with little time, consider booking a flight, which has an average total journey time of 5h 23m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a bus costs an average of $105, while a flight costs an average of $426.
Distance: 395 miles (637 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$105 Average price Cheapest | $188 Average price | $426 Average price | $252 Average price (fuel + tolls) |
17h 12m Average total duration 16h 42m Onboard + 30m Additional time* | 9h 24m Average total duration 8h 54m Onboard + 30m Additional time* | 5h 23m Average total duration Fastest 3h 23m Onboard + 2h 0m Additional time* | 9h 13m Average total duration (door-to-door) |
0.6 - 1.6kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | 1.9 - 3.8kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lugano to Brussels:
A bus is $92 (€77) less than a train for this route with tickets for a train from Lugano to Brussels costing on average $212 (€177).
A bus is $306 (€256) less than a flight for this route with tickets for a flight from Lugano to Brussels costing on average $426 (€356).
Other travel options to Brussels take longer:
Train takes on average 9h 31m.
Bus takes on average 17h 11m.
Tickets start at around $120 (€101) compared to roughly $252 (€210) in fuel and tolls — a saving of about $132 (€110). The journey takes 16h 41m versus 9h 13m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Lugano to Brussels
How to get from Lugano to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Lugano to Brussels is by taking a flight because it’s the best combination of price and speed.
FR 36596:15 AM1h35Milan Bergamo Orio al Serio Airport7:50 AMBrussels South Charleroi Airport$281One-way0 transfers
Cheapest
FR 36596:15 AM1h35Milan Bergamo Orio al Serio Airport7:50 AMBrussels South Charleroi Airport$281One-way0 transfers
Fastest
SN31609:45 PM1h30Milan Malpensa Airport11:15 PMBrussels Airport$1291One-way0 transfers
Other options
IC 672 · ICE 106 · ICE 1210:02 AM9h33Lugano station7:35 PMBrussels-Midi$1081One-way2 transfers
IC 668 · ICE 108 · ICE 148:02 AM9h33Lugano station5:35 PMBrussels-Midi$1681One-way2 transfers
47399:10 PM11h30Lugano, Via Ciani8:40 AMBrussels, Brussels South (Gare du Midi)$481One-way0 transfers
47434:35 PM12h20Lugano, Via Ciani4:55 AMBrussels, Brussels South (Gare du Midi)$481One-way0 transfers
FlixBus · FlixBus · FlixBus4:20 PM21h35Lugano, Via Ciani1:55 PMBrussels, Brussels South (Gare du Midi)$701One-way2 transfers
FR 447510:20 AM1h35Milan Bergamo Orio al Serio Airport11:55 AMBrussels South Charleroi Airport$541One-way0 transfers
U254337:00 AM1h35Milan Linate Airport8:35 AMBrussels Airport$611One-way0 transfers
FR 45239:10 PM1h35Milan Bergamo Orio al Serio Airport10:45 PMBrussels South Charleroi Airport$721One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Lugano to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lugano to Brussels.

This is compared to other travel options from Lugano to Brussels:
A bus is $92 (€77) less than a train for this route with tickets for a train from Lugano to Brussels costing on average $212 (€177).
A bus is $306 (€256) less than a flight for this route with tickets for a flight from Lugano to Brussels costing on average $426 (€356).
Other travel options to Brussels take longer:
Train takes on average 9h 31m.
Bus takes on average 17h 11m.
- Around 48 flights per day.
- Around 5 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Lugano and Brussels as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Milan Linate Airport and arrive in Brussels Airport.
- Trains mostly depart from Lugano station and arrive in Brussels-Midi.
- Buses mostly depart from Lugano, Via Ciani and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with BlaBlaCar Bus, FlixBus to go to Brussels by bus.
- Travel with Deutsche Bahn to go to Brussels by train.
- Travel with Malta Air, Ryanair, ITA, Brussels Airlines, KLM Cityhopper, Swiss, BA Cityflyer, KLM, Qatar Airways, Air Dolomiti, Austrian Airlines, Lufthansa, Gulf Air, Vueling, AJet, Air Baltic, Turkish Airlines, Helvetic Airways, British Airways, Edelweiss Air, easyJet to go to Brussels by flight.
- 1 direct buses per day with BlaBlaCar Bus.
- 11 direct flights per day with Malta Air, Ryanair, ITA, Brussels Airlines, Air Baltic, easyJet.
Travelling from Lugano to Brussels: related information
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