- Must visit
Vatican Museums
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and major classical and Renaissance collections. Timed entry is strongly recommended due to very high demand.
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The cheapest and fastest trains from Mestre to Rome
Showing times and prices for Jun 20
Cheapest price
$66
Average price
$100
Fastest journey
4 h 7 m
Average duration
4 h 17 m
Trains per day
32
Distance
400 km
Cheap tickets
The best way to find a cheap train ticket from Mestre to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mestre to Rome will cost around $100 if you buy it on the day, but the cheapest tickets can be found for only $66.
Fast trains
It's difficult to get from Mestre to Rome without transferring at least once.
Regionale 16826 · Regionale Veloce 3898+
InterCityNotte 7709:02 PM9h33Venezia Mestre Ospedale6:35 AMRome Termini$661One-way2 transfers- Regionale 16825+InterCityNotte 7708:28 PM10h07Venezia Mestre Ospedale6:35 AMRome Termini$661One-way1 transfer
- Regionale 16825 · Regionale Veloce 3518+InterCityNotte 7638:28 PM9h38Venezia Mestre Ospedale6:06 AMRome Termini$701One-way2 transfers
- Regionale 16874+
Intercity 5848:58 AM7h22Venezia Mestre Ospedale4:20 PMRome Termini$701One-way1 transfer - Regionale 16787+Intercity 5942:28 PM7h52Venezia Mestre Ospedale10:20 PMRome Termini$701One-way1 transfer
- Regionale 16870+
FRECCIAROSSA 94667:58 AM4h07Venezia Mestre Ospedale12:05 PMRome Termini$1141One-way1 transfer - Regionale 16037+FRECCIAROSSA 94015:18 AM4h15Venezia Mestre Ospedale9:33 AMRome Termini$1141One-way1 transfer
- Regionale 16836 · Regionale Veloce 3637+FRECCIAROSSA 94057:04 AM4h18Venezia Mestre Ospedale11:22 AMRome Termini$1141One-way2 transfers
- Regionale 16845+FRECCIAROSSA 94035:56 AM4h18Venezia Mestre Ospedale10:14 AMRome Tiburtina$1141One-way1 transfer
- Regionale 16232+FRECCIAROSSA 841911:58 AM4h26Venezia Mestre Ospedale4:24 PMRome Termini$1141One-way1 transfer
Travel Information
Compare train, bus, and flight for Mestre to Rome
Omio recommends booking the train as it is the most popular option from Mestre to Rome among Omio's users. If you are prioritising price take the train with prices starting from $26. For those with little time consider booking a flight which can get you there in 1h 9m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a train costs an average of $26, and a flight costs an average of $83.
Distance: 248 miles (400 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$57 Average price Cheapest | $70 Average price | $149 Average price | $156 Average price (fuel + tolls) |
6h 56m Average total duration 6h 26m Onboard + 30m Additional time* | 7h 21m Average total duration 6h 51m Onboard + 30m Additional time* | 4h 9m Average total duration Fastest 1h 9m Onboard + 3h 0m Additional time* | 5h 10m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.2 - 2.4kg CO2 emissions | - CO2 emissions |
Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Mestre to Rome is a train with an average price of $57 (€47).
This is compared to other travel options from Mestre to Rome:
A train is $13 (€11) less than a bus for this route with tickets for a bus from Mestre to Rome costing on average $70 (€58).
A train is $92 (€76) less than a flight for this route with tickets for a flight from Mestre to Rome costing on average $149 (€123).
The fastest way to travel from Mestre to Rome is by flight with an average journey time of 1h 9m.
Other travel options to Rome take longer:
Train takes on average 6h 26m.
Bus takes on average 6h 51m.
It's helpful to compare your options as there are 3 ways to travel between Mestre and Rome including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Mestre to Rome among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around {cheapestPrice} compared to roughly {drivingPriceInCents} in fuel and tolls — a saving of about {savingsAmount}. The journey takes {durationInMinutes} versus {drivingDurationInMinutes} by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Direct services run with Frecciarossa, Italo, Intercity.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Mestre to Rome train times
The table below shows live departures for Mestre to Rome trains for today, Friday, June 19. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| Regionale 16121+FRECCIAROSSA 8801 · FRECCIAROSSA 9611 | 6:26 AM Venezia Mestre Ospedale | 4h44 | 11:10 AM Rome Termini | 2 transfers | |
| Regionale 16757+FRECCIAROSSA 9405 | 6:56 AM Venezia Mestre Ospedale | 4h26 | 11:22 AM Rome Termini | 1 transfer | |
| Regionale 16836 · Regionale Veloce 3637+FRECCIAROSSA 9405 | 7:04 AM Venezia Mestre Ospedale | 4h18 | 11:22 AM Rome Termini | 2 transfers | |
| Regionale 16870+FRECCIAROSSA 9466 | 7:58 AM Venezia Mestre Ospedale | 4h07 | 12:05 PM Rome Termini | 1 transfer | |
| Regionale 16811 · Regionale Veloce 3967+FRECCIAROSSA 9619 | 8:36 AM Venezia Mestre Ospedale | 4h34 | 1:10 PM Rome Termini | 2 transfers | |
| Regionale 16874+FRECCIAROSSA 9411 | 8:58 AM Venezia Mestre Ospedale | 4h32 | 1:30 PM Rome Termini | 1 transfer | |
| Regionale 16726 · Regionale 3997+FRECCIAROSSA 9623 | 9:28 AM Venezia Mestre Ospedale | 4h42 | 2:10 PM Rome Termini | 2 transfers | |
| Regionale 16680+Intercity 584 | 9:58 AM Venezia Mestre Ospedale | 10h07 | 8:05 PM Rome Termini | 1 transfer | |
| Regionale 16777 · Regionale Veloce 3975+FRECCIAROSSA 9637 | 12:26 PM Venezia Mestre Ospedale | 4h44 | 5:10 PM Rome Termini | 2 transfers | |
| Regionale 16777+FRECCIAROSSA 9421 | 12:26 PM Venezia Mestre Ospedale | 4h58 | 5:24 PM Rome Termini | 1 transfer | |
| Regionale 16783+FRECCIAROSSA 9425 | 1:56 PM Venezia Mestre Ospedale | 4h29 | 6:25 PM Rome Termini | 1 transfer | |
| Regionale 16787 · Regionale Veloce 3979+FRECCIAROSSA 9645 | 2:28 PM Venezia Mestre Ospedale | 4h47 | 7:15 PM Rome Termini | 2 transfers | |
| Regionale 16791+FRECCIAROSSA 9427 | 2:58 PM Venezia Mestre Ospedale | 4h27 | 7:25 PM Rome Termini | 1 transfer | |
| Regionale 16791+Intercity 594 | 2:58 PM Venezia Mestre Ospedale | 7h22 | 10:20 PM Rome Termini | 1 transfer | |
| Regionale 16793 · Regionale Veloce 3981+FRECCIAROSSA 9649 | 3:26 PM Venezia Mestre Ospedale | 4h49 | 8:15 PM Rome Termini | 2 transfers | |
| Regionale 16768+FRECCIAROSSA 9431 | 3:58 PM Venezia Mestre Ospedale | 4h27 | 8:25 PM Rome Termini | 1 transfer | |
| Regionale 16801 · Regionale Veloce 3983+FRECCIAROSSA 9653 | 4:28 PM Venezia Mestre Ospedale | 4h42 | 9:10 PM Rome Termini | 2 transfers | |
| Regionale 16805+FRECCIAROSSA 9433 | 4:56 PM Venezia Mestre Ospedale | 4h34 | 9:30 PM Rome Termini | 1 transfer | |
| Regionale 16809 · Regionale Veloce 3985+FRECCIAROSSA 9661 | 5:26 PM Venezia Mestre Ospedale | 4h44 | 10:10 PM Rome Termini | 2 transfers | |
| Regionale 16852+FRECCIAROSSA 9435 | 5:58 PM Venezia Mestre Ospedale | 4h27 | 10:25 PM Rome Termini | 1 transfer | |
| Regionale 16258+FRECCIAROSSA 9437 | 6:58 PM Venezia Mestre Ospedale | 4h32 | 11:30 PM Rome Termini | 1 transfer | |
| Saturday, June 20 | |||||
| Regionale 16037+FRECCIAROSSA 9401 | 5:18 AM Venezia Mestre Ospedale | 4h15 | 9:33 AM Rome Termini | 1 transfer | |
| Regionale 16037 · Regionale Veloce 3961+Intercity 583 | 5:18 AM Venezia Mestre Ospedale | 8h50 | 2:08 PM Rome Ostiense | 2 transfers | |
| Regionale 16845+FRECCIAROSSA 9403 | 5:56 AM Venezia Mestre Ospedale | 4h18 | 10:14 AM Rome Tiburtina | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mestre to Rome by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Mestre to Rome trains with Omio?
Frecciarossa as well as Italo, Intercity Notte, Intercity, Regionale and more offer trains services from Mestre to Rome.
Omio is an official ticket reseller for all your travel options from Mestre to Rome.
Why book with Omio vs Frecciarossa?
- Compare with other providers: On Omio, you can not only buy tickets for Frecciarossa, but also compare tickets for the likes of Italo, Intercity Notte, Intercity or Regionale to find the best option for your trip from Mestre to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Frecciarossa with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Mestre to Rome.
Why book with Omio over Raileurope?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Mestre to Rome.
How far in advance should I book train tickets from Mestre to Rome?
The best time to book your train from Mestre to Rome is 63 days before departure. See how prices for trains change on the Mestre to Rome route.
Prices are for one-way tickets for one passenger from Mestre to Rome per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from Mestre to Rome.
Trains
from $33Buses
from $11Flights
from $78Journey information
Overview: Train from Mestre to Rome
ItalyItaly
Trains from Mestre to Rome run on average 25 times per day, taking around 6h 26m. Cheap train tickets for this journey start at $26 (€21) but you can travel from only $22 (€18) by bus.
There are 2 trains per day. The earliest train runs at 00:15, the last at 23:49. The fastest train covers the 248 miles (400 km) distance in 7h 22m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $22 (€18)
Distance 248 miles (400 km) |
Average train duration 6h 26m |
Cheapest ticket price $26 (€21) |
Trains per day 25 |
Direct trains 2 |
Fastest train 7h 22m |
First train 12:15 AM |
Last train 11:49 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Tue |
Best time to book 77 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $22 (€18)
Train companies: Frecciarossa, Italo, Intercity Notte, Intercity, Regionale from Mestre to Rome trainsFrecciarossa, Italo, Intercity Notte, Intercity, Regionale trains will get you between Mestre and Rome from $22 (€18). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Duration
3h 31m
Cheapest Price
$116 (€95)
Frecciarossa frequency
14 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Italo
About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Average Duration
3h 45m
Cheapest Price
$92 (€75)
Italo frequency
9 a day
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone
Intercity Notte
About
Intercity Notte is an Italian train service operated by Trenitalia. It runs overnight services between major cities in Italy, making it a great option for travelers looking to save time and money. The Intercity Notte offers two types of trains: the Frecciarossa Notte and the Frecciargento Notte. The Frecciarossa Notte is the fastest train, with speeds of up to 300 km/h, while the Frecciargento Notte is slightly slower but still offers a comfortable journey. Both trains offer a range of onboard facilities, including comfortable seating, air conditioning, and Wi-Fi. Trenitalia offers a range of ticket types, including Standard, Comfort, and Business. Standard tickets are the most affordable, while Comfort and Business tickets offer additional benefits such as priority boarding and access to the lounge. The most popular routes for Intercity Notte are Rome to Milan, Rome to Venice, and Milan to Venice. These routes offer travelers the chance to explore some of Italy's most iconic cities in a convenient and comfortable way.
Luggage & cancellation policy
Average Duration
8h 37m
Cheapest Price
$35 (€28)
Luggage included
1 handbag and 1 suitcase included in ticket price
Luggage storage
Luggage racks above seats and at carriage ends
Cancellation Policy
Cancellation possible according to ticket type conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full dining service and bar
Seat reservation
Seat reservation included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for disabled passengers
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs free.
Quiet zone
Intercity
About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Duration
7h 22m
Cheapest Price
$26 (€21)
Intercity frequency
2 a day
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
9h 52m
Cheapest Price
$60 (€49)
Regionale frequency
2 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
Complete guide to Rome
Things to do in Rome
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
- Must visit
Galleria Borghese
One of Rome’s finest art museums, known for Bernini sculptures and paintings by Caravaggio and Raphael. Advance reservation is typically required because entry is strictly timed.
- Recommended
Capitoline Museums
The city’s historic civic museums on Capitoline Hill, featuring Roman bronzes, imperial sculpture, and art with views over the Forum.
- Must visit
Piazza Navona
Elegant Baroque square built on an ancient stadium, lined with fountains, palaces, and lively street life. A classic area for strolling and people-watching.
- Must visit
Trastevere
Atmospheric neighborhood of narrow lanes, ivy-covered buildings, and busy evening streets. Popular with visitors but still one of Rome’s most characteristic areas.
- Must visit
Spanish Steps
Famous monumental staircase linking Piazza di Spagna and Trinità dei Monti. A highly photographed landmark and social-media favorite.
- Vegetarian
Cacio E Pepe
A classic Roman pasta with pecorino Romano and black pepper. It is one of the city’s most iconic dishes and a benchmark of Roman cooking.
Carbonara
Traditional Roman pasta made with guanciale, egg yolk, pecorino Romano, and black pepper. It is famous for its rich sauce without cream.
Amatriciana
A beloved pasta sauce of tomato, guanciale, and pecorino Romano, closely tied to Rome’s culinary identity and served with bucatini or rigatoni.
La Pergola
Rome’s most famous fine-dining restaurant, offering elegant tasting menus, panoramic views, and one of the city’s most prestigious dining experiences.
Armando Al Pantheon
A historic trattoria near the Pantheon, famous for traditional Roman dishes such as gricia, amatriciana, and seasonal specialties.
Roscioli Salumeria Con Cucina
A celebrated central Rome venue known for classic Roman pasta, exceptional cured meats, and a refined but lively atmosphere.
Euro
Rome is moderate by Western Europe standards: sights are affordable, but central hotels and tourist-area dining cost more.
Average meal costs
- Budget
- EUR 8-15 for pizza, panini, or street food.
- Mid-range
- EUR 20-40 per person for a casual restaurant meal.
- Fine dining
- EUR 80+ per person at upscale restaurants.
- Coffee
- EUR 1.20-2.50 for espresso or cappuccino.
Tipping culture
Service is usually included or modest. Tipping is not required, but rounding up or leaving EUR 1-2 at cafes and 5-10% at restaurants for good service is appreciated.
Moovit
Get the appOfficial public transport app
Prices
- Single ticket
- EUR 1.50
- Day pass
- EUR 7.00
To the city center
Rome Termini, Rome -> Piazza Venezia, Rome
- Distance
- 2 km
- Travel time
- 10 min
- Tap-and-go card payment is available on Rome metro, buses and trams for single journeys; validate paper tickets before boarding or at metro gates.
- A BIT ticket is valid for 100 min on buses, trams and metro, but only one metro entry is included.
FAQs: Trains from Mestre to Rome
Find answers to the most common questions about traveling from Mestre to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.
Train ticket prices from Mestre to Rome can vary. The cheapest ticket starts at $26 (€21), while the average price is around $57 (€47).
The train from Mestre to Rome takes 7h 22m and runs 25 per day.
The distance by train from Mestre to Rome is 248 miles (400 km).
The first train from Mestre to Rome leaves at 12:15 AM.
The last train from Mestre to Rome leaves at 11:49 PM.
Yes, there is a high-speed train from Mestre to Rome.
Yes, there is a direct train from Mestre to Rome. This service operates 2 times per day, provided by Frecciarossa, Italo, Intercity.
Yes, there is a night train from Mestre to Rome.
The train station in Mestre that goes to Rome is Venezia Mestre Ospedale, which connects to Rome Termini.
The cheapest way to get from Mestre to Rome is by bus, with a cost of around $22 (€18).
The train journey from Mestre to Rome offers scenic views primarily in the first half, as it passes through picturesque vineyards and rolling hills of the Veneto and Emilia-Romagna regions. However, the landscape becomes more urban and industrial closer to Rome.
A day trip from Mestre to Rome is not feasible as the journey takes 7h 22m. The distance is 248 miles (400 km). Trains run 24 times per day.
In Rome, explore Trastevere's charming streets and nightlife, stroll through Villa Borghese's parks and museums, enjoy gelato at the lively Piazza Navona, and visit the Spanish Steps for views and people-watching. Discover the ancient Catacombs with guided tours, and don't miss the best sights: the iconic Colosseum, the art-filled Vatican Museums including the Sistine Chapel, the ruins of the Roman Forum, the well-preserved Pantheon, and the famous Trevi Fountain where you can toss a coin for good luck.
To experience Rome's main attractions, a stay of 3 to 4 days is generally recommended, allowing time to visit landmarks like the Colosseum, Vatican City, and explore local neighborhoods.
Yes, you can take the train from Mestre to Rome.
Since both Mestre and Rome are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Rome include Civitavecchia, Fiumicino, Tivoli, Orvieto, Anzio.
We recommend using the train as it is the most popular way to get from Mestre to Rome among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Rome, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, major landmarks, and popular squares. Common scams include unofficial taxi drivers overcharging and street vendors selling counterfeit goods. It's advisable to use authorized taxis, keep valuables secure, and be wary of distraction techniques used by scammers in busy tourist spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Mestre to Rome
Most Mestre to Rome trains use the Venezia Mestre Ospedale to Roma Termini station pair, with some services arriving at Roma Tiburtina. Use this guide to compare Mestre and Rome train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in Mestre
Arrival train stations in Rome
Which Mestre station do trains to Rome leave from?
Trains from Mestre to Rome leave from Venezia Mestre Ospedale. The station is 1 miles (3 km) from Mestre city centre at Via Don Federico Tosatto, 30174 Mestre, Venice, Italy.
Venezia Mestre OspedaleVia Don Federico Tosatto, 30174 Mestre, Venice, Italy+39 041 272 2111
City-centre transport
Getting to Venezia Mestre Ospedale from Mestre city centre
Venezia Mestre Ospedale is 2 km from Mestre city centre. Public transport options include:
TrainRe · 7m · $1 · every ~2 min
Bus32H, 48H, 33H, 34H, 31H · 46m · $2 · every ~5 min
Venezia Mestre Ospedale train station facilities and services
Venezia Mestre Ospedale has practical services for this route, including Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, and Information Desk.
Food and drink
Food and drink options are available at Venezia Mestre Ospedale.
Tickets and information
Ticket office support is available at Venezia Mestre Ospedale. Information desks are located near the main entrance.
Parking, taxis and toilets
Available at Venezia Mestre Ospedale: Parking, Taxis, WC.
Bike and car services
Available at Venezia Mestre Ospedale: Bike Parking.
Accessibility
Accessibility facilities are available at Venezia Mestre Ospedale.
Shops, hotels and contact
Nearby hotels include Hotel Villa Sara, Hotel Altieri, Hotel Ducale.
Which Rome station do trains from Mestre arrive at?
Trains from Mestre to Rome most often arrive at Roma Termini. Some services arrive at Roma Tiburtina, so check your ticket before travel to confirm your Rome arrival station.
Roma TerminiPiazza dei Cinquecento 1, 00185 Rome, Italy+39 064745421
City-centre transport
Getting to Roma Termini from Rome city centre
Roma Termini is 1 km from Rome city centre. Public transport options include:
Metro linesA (red), B (blue)
Bus lines5, H, 38, 40 Express, 50 Express, 64, 66, 70, 75, 82, 90 Express, 92, 105, 150F, 223, 310, 590, 714, 910, C2, C3
Tram lines5, 14
Train linesItalo, FR, FA, FB, IC, ICN, EN, CNL, R, Leonardo Express
Roma Termini train station facilities and services
Roma Termini has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental, and Information Desk.
Food and drink
Food options include: Acafe, Moka Café, Roadhouse Grill, McDonald's, Gusto, Chef Express, Coop Minimarket, Mercato Centrale
Wi-Fi and ATMs
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
Tickets and information
The ticket office is open Mon - Sun: 06:30 - 22:00. Information desks are located near Platform 24.
Luggage and lost property
Luggage storage is provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
Parking, taxis and toilets
Available at Roma Termini: Parking, Taxis, WC.
Bike and car services
Available at Roma Termini: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Roma Termini: The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
Shops, hotels and contact
Nearby hotels include Archi di Roma Guest House, Gemma di Roma, The Liberty Boutique Hotel.
Roma TiburtinaPiazzale Stazione Tiburtina, 00162 Roma RM, Italy+39 892021
City-centre transport
Getting to Roma Tiburtina from Rome city centre
Roma Tiburtina is 4 km from Rome city centre. Public transport options include:
Train8914, 9970, 9948, 9946, 9924, 9916, 9912, 9904, 8928, 8924, 8918, 8922, 8908, 8906, 8904, 8900, 8134, 9944, 9966, 9920, 9908, 8916, 8910, 9954, 9940 · 5m · $1 · every ~6 min
Bus490, 495 · 24m · $2 · every ~22 min
SubwayMeb · 13m · $2 · every ~15 min
Roma Tiburtina train station facilities and services
Roma Tiburtina has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental, and Information Desk.
Food and drink
Food options include: Rock n’ Coffee Roma, Arabian Kebab, Ingredienti, McDonald’s, Numb's Bakery Café
Wi-Fi and ATMs
Free, limited Wi-Fi available in the station for 15 minutes. ATMs are located on the ground floor level.
Tickets and information
The ticket office is open Mon - Sun: 06:35 - 20:20. Information desks are located inside the main terminal. .
Luggage and lost property
Luggage storage is luggage lockers are located in the station lobby.
Parking, taxis and toilets
Available at Roma Tiburtina: Parking, Taxis, WC.
Bike and car services
Available at Roma Tiburtina: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Roma Tiburtina: Accessible facilities include elevators and escalators.
Shops, hotels and contact
Nearby hotels include B&B Rome Tiburtina, B&B Alba Domus Roma, Hotel delle Province.
Roma OstiensePiazzale dei Partigiani, 00154 Rome, Italy+39 06 575 5310
City-centre transport
Getting to Roma Ostiense from Rome city centre
Roma Ostiense is 2 km from Rome city centre. Public transport options include:
TrainRe, 4140, 4138, 4136, 4134, 4130, 34474, 34476, 34488, 34482, 34480, 4132, 4128 · 11m · $1 · every ~4 min
BusnMB, n716 · 19m · $2 · every ~6 min
nMB, n716 · 22m · $2 · every ~6 min
SubwayMeb, Meb1 · 12m · $2 · every ~29 min
Roma Ostiense train station facilities and services
Roma Ostiense has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Ramen Bar Akira, Eataly Roma
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Roma Ostiense. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Roma Ostiense. Lost and found is available at the station.
Parking, taxis and toilets
Available at Roma Ostiense: Parking, Taxis, WC.
Bike and car services
Available at Roma Ostiense: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Roma Ostiense: Elevators, ramps, restrooms.
Shops, hotels and contact
Nearby hotels include Hotel Abitart, Hotel San Anselmo, Hotel Villa San Pio.
Most popular train connections from Mestre
More options for your journey from Mestre to Rome
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Most popular trains to and from Rome and Mestre
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