The cheapest and fastest buses from Venice Mestre to Florence Santa Maria Novella
Cheapest price
$16
Average price
$32
Fastest journey
2 h 20 m
Average duration
2 h 32 m
Buses per day
8
Distance
205 km
The best way to find a cheap bus ticket from Venice Mestre to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Venice Mestre to Florence Santa Maria Novella will cost around $32 if you buy it on the day, but the cheapest tickets can be found for only $16.
Of the 8 buses that leave Venice Mestre for Florence Santa Maria Novella on Sun, Nov 23, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Nov 23 the direct buses cover the 205 km distance in an average of 2 h 32 m but if you time it right, some buses will get you there in just 2 h 20 m .
On Sun, Nov 23 the slowest buses will take 2 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare bus and train for Venice Mestre to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Venice Mestre to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from €7. For those with little time consider booking a train which can get you there in 3h 25m. The ticket price range depends on the travel mode: a bus costs an average of €7, and a train costs an average of €21.
Distance: 127 miles (205 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€21 Average price Cheapest | €36 Average price |
4h 25m Average total duration 3h 55m Onboard + 30m Additional time* | 3h 55m Average total duration Fastest 3h 25m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Venice Mestre to Florence Santa Maria Novella Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 07:00AM | Arrival Time 09:20AM | Duration 2h20 | Departure days Sun | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 07:30AM | Arrival Time 10:30AM | Duration 3h00 | Departure days Wed | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 08:20AM | Arrival Time 11:10AM | Duration 2h50 | Departure days Sun | Cheapest price $24 |
Operator BlaBlaCar | Departure Time 08:50AM | Arrival Time 11:10AM | Duration 2h20 | Departure days Mon | Cheapest price $21 |
Operator BlaBlaCar | Departure Time 09:10AM | Arrival Time 12:20PM | Duration 3h10 | Departure days Mon, Fri | Cheapest price $23 |
Operator BlaBlaCar | Departure Time 09:30AM | Arrival Time 12:10PM | Duration 2h40 | Departure days Sat | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 12:20PM | Duration 2h20 | Departure days Mon | Cheapest price $23 |
Operator BlaBlaCar | Departure Time 10:30AM | Arrival Time 01:20PM | Duration 2h50 | Departure days Sat | Cheapest price $26 |
Operator BlaBlaCar | Departure Time 12:30PM | Arrival Time 03:00PM | Duration 2h30 | Departure days Sun | Cheapest price $16 |
Operator BlaBlaCar | Departure Time 12:50PM | Arrival Time 03:40PM | Duration 2h50 | Departure days Sat | Cheapest price $30 |
Operator BlaBlaCar | Departure Time 02:20PM | Arrival Time 04:40PM | Duration 2h20 | Departure days Mon | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 02:30PM | Arrival Time 05:20PM | Duration 2h50 | Departure days Mon | Cheapest price $31 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 05:30PM | Duration 2h30 | Departure days Sun | Cheapest price $24 |
Operator Trenitalia | Departure Time 04:53PM | Arrival Time 09:37PM | Duration 4h44 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $28 |
Operator BlaBlaCar | Departure Time 06:00PM | Arrival Time 08:30PM | Duration 2h30 | Departure days Sun | Cheapest price $19 |
Operator BlaBlaCar | Departure Time 07:00PM | Arrival Time 10:00PM | Duration 3h00 | Departure days Tue | Cheapest price $28 |
Operator FlixBus | Departure Time 07:15PM | Arrival Time 11:00PM | Duration 3h45 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $8 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 01:30AM | Duration 4h20 | Departure days Wed, Fri, Sat, Sun | Cheapest price $15 |
Live departures
Venice Mestre to Florence Santa Maria Novella bus times
The table below shows live departures for Venice Mestre to Florence Santa Maria Novella buses for today, Saturday, November 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale Veloce 3983+ BUS L599B | 3:53 PM Venice Mestre | 4h44 | 8:37 PM Florence Santa Maria Novella | 1 transfer | |
FlixBus | 6:15 PM Venezia, Viale Stazione / Via Dante (Mestre Stazione) | 3h45 | 10:00 PM Firenze, Piazzale Montelungo | 0 transfersDirect | |
FlixBus | 8:10 PM Venezia, Viale Stazione / Via Dante (Mestre Stazione) | 4h20 | 12:30 AM Firenze, Piazzale Montelungo | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Venice Mestre to Florence Santa Maria Novella by bus or train
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Journey information
Overview: Bus from Venice Mestre to Florence Santa Maria Novella
Buses from Venice Mestre to Florence Santa Maria Novella run on average 7 times per day, taking around 3h 55m. Cheap bus tickets for this journey start at $9 (€7) if you book in advance.
There are 3 buses per day. The earliest bus runs at 14:53, the last at 21:59. The fastest bus covers the 127 miles (205 km) distance in 3h 45m.
Distance 127 miles (205 km) |
Average bus duration 3h 55m |
Cheapest ticket price $9 (€7) |
Buses per day 7 |
Direct buses 3 |
Fastest bus 3h 45m |
First bus 14:53 |
Last bus 21:59 |
Bus providers: Itabus, FlixBus, BlaBlaCar, Marino Autolinee from Venice Mestre to Florence Santa Maria NovellaYou can travel by bus between Venice Mestre to Florence Santa Maria Novella with Itabus, FlixBus, BlaBlaCar, Marino Autolinee for as low as $9 (€7). When you search for schedules and tickets, Omio will show you the best journey
Itabus
FlixBus
Marino Autolinee
BlaBlaCar
FAQs: Bus from Venice Mestre to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Venice Mestre to Florence Santa Maria Novella by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
To find the cheapest bus tickets for your trip from Venice Mestre to Florence Santa Maria Novella, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- 5€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- Itabus
- Small pets allowed in carriers
- Larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
- Marino Autolinee
- Small pets allowed in carriers
- Larger pets must be leashed and muzzled.
Most popular bus connections from Venice Mestre
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