- Must visit
Pinacoteca di Brera
One of Milan’s premier art museums, known for Italian masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Cheapest price
$66
Average price
$66
Fastest journey
7 h 56 m
Average duration
7 h 56 m
Trains per day
1
Distance
541 km
The best way to find a cheap train ticket from Sezze Romano to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Sezze Romano to Milan Centrale will cost around $66 if you buy it on the day, but the cheapest tickets can be found for only $66.
Of the 1 trains that leave Sezze Romano for Milan Centrale on Wed, Jun 03, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jun 03 the direct trains cover the 541 km distance in an average of 7 h 56 m but if you time it right, some trains will get you there in just 7 h 56 m .
On Wed, Jun 03 the slowest trains will take 7 h 56 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from Sezze Romano to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $12. For those with little time consider booking a flight which can get you there in 1h 13m. The ticket price range depends on the travel mode: a bus costs an average of $12, and a flight costs an average of $63.
Distance: 336 miles (541 km)
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
$64 Average price | $144 Average price | $24 Average price Cheapest | $130 Average price (fuel + tolls) |
6h 9m Average total duration 5h 39m Onboard + 30m Additional time* | 4h 13m Average total duration Fastest 1h 13m Onboard + 3h 0m Additional time* | 10h 5m Average total duration 9h 35m Onboard + 30m Additional time* | 7h 9m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Sezze Romano to Milan Centrale:
A bus is $40 (€32) less than a train for this route with tickets for a train from Sezze Romano to Milan Centrale costing on average $64 (€51).
A bus is $119 (€96) less than a flight for this route with tickets for a flight from Sezze Romano to Milan Centrale costing on average $144 (€116).
Other travel options to Milan Centrale take longer:
Train takes on average 5h 39m.
Bus takes on average 9h 35m.
The journey is about 1h 30m faster (5h 39m by train vs 7h 9m by car) and roughly $66 (€54) cheaper once you factor in fuel and tolls ($64 (€51) vs $130 (€105)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Sezze Romano to Milan Centrale trains for today, Tuesday, June 2. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:29 AM Sezze Romano | 7h56 | 6:25 PM Milan Centrale | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Sezze Romano to Milan Centrale run on average 22 times per day, taking around 5h 39m. Cheap train tickets for this journey start at $45 (€36) but you can travel from only $12 (€10) by bus.
The earliest train runs at 09:18, the last at 20:29. The fastest train covers the 336 miles (541 km) distance in 7h 56m.
Distance 336 miles (541 km) |
Average train duration 5h 39m |
Cheapest ticket price $45 (€36) |
Trains per day 22 |
Fastest train 7h 56m |
First train 9:18 AM |
Last train 8:29 PM |
Cheapest Month Jul |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Oct - Dec |
Discover the best of Milano Centrale — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milano Centrale trip today.
One of Milan’s premier art museums, known for Italian masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
The museum site hosting Leonardo da Vinci’s Last Supper at Santa Maria delle Grazie, one of Milan’s most sought-after cultural visits.
A leading museum of 20th-century Italian art overlooking Piazza del Duomo, with strong Futurist and modern collections.
Milan’s main square and the city’s symbolic heart, ideal for first-time visitors, landmark views, and people-watching.
A charming historic neighborhood of narrow streets, elegant buildings, galleries, and boutiques, popular for strolling and atmosphere.
Milan’s canal-side area known for scenic walks, bridges, and lively urban character, especially photogenic in the evening.
Creamy saffron risotto, the signature dish of Milan, prized for its rich flavor and golden color.
Breaded veal cutlet fried in butter, a classic Milanese main course with a crisp exterior and tender meat.
Braised veal shanks, often served with risotto, loved in Milan for its deep, slow-cooked flavor.
Elegant fine-dining venue at Excelsior Hotel Gallia near Milano Centrale, known for upscale Italian cuisine.
Established Michelin-starred restaurant celebrated for creative vegetarian cuisine and a distinctive fine-dining experience.
Well-known modern Milanese restaurant serving refined Lombard classics in a stylish, contemporary setting.
Generally pricier than many Italian cities, especially near the station. Budget eats are manageable, but hotels and sit-down dining cost more.
Service is often included or covered by a coperto charge. Tipping is not mandatory, but rounding up or leaving EUR 1-2 at cafes and 5-10% at restaurants for good service is appreciated.
Official public transport app
Milano Centrale, Milan -> Duomo di Milano, Milan
Find answers to the most common questions about traveling from Sezze Romano to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need