- Must visit
Vatican Museums
A vast complex of papal collections including classical sculpture, Renaissance masterpieces, the Raphael Rooms, and access to the Sistine Chapel. One of Rome’s most important art visits and often best
Cheapest price
$44
Average price
$44
Fastest journey
9 h 2 m
Average duration
9 h 2 m
Trains per day
1
Distance
518 km
The best way to find a cheap train ticket from Santhià station to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santhià station to Rome will cost around $44 if you buy it on the day, but the cheapest tickets can be found for only $44.
Of the 1 trains that leave Santhià station for Rome on Fri, May 29, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, May 29 the direct trains cover the 518 km distance in an average of 9 h 2 m but if you time it right, some trains will get you there in just 9 h 2 m .
On Fri, May 29 the slowest trains will take 9 h 2 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the train as it is the most popular option from Santhià station to Rome among Omio's users. If you are prioritising price take the bus with prices starting from $37. For those with little time consider booking a flight which can get you there in 1h 12m. The ticket price range depends on the travel mode: a bus costs an average of $37, and a flight costs an average of $74.
Distance: 321 miles (518 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$69 Average price | $45 Average price Cheapest | $102 Average price | $132 Average price (fuel + tolls) |
6h 19m Average total duration 5h 49m Onboard + 30m Additional time* | 11h 49m Average total duration 11h 19m Onboard + 30m Additional time* | 4h 12m Average total duration Fastest 1h 12m Onboard + 3h 0m Additional time* | 6h 26m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santhià station to Rome:
A bus is $24 (€20) less than a train for this route with tickets for a train from Santhià station to Rome costing on average $69 (€56).
A bus is $57 (€46) less than a flight for this route with tickets for a flight from Santhià station to Rome costing on average $102 (€82).
Other travel options to Rome take longer:
Train takes on average 5h 49m.
Bus takes on average 11h 19m.
The journey is about 37m faster (5h 49m by train vs 6h 26m by car) and roughly $63 (€51) cheaper once you factor in fuel and tolls ($69 (€56) vs $132 (€107)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
The table below shows live departures for Santhià station to Rome trains for today, Thursday, May 28. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:04 AM Santhià station | 5h31 | 12:35 PM Rome | 1 transfer | |
![]() | 8:13 AM Santhià station | 5h22 | 1:35 PM Rome | 1 transfer | |
![]() | 12:38 PM Santhià station | 5h41 | 6:19 PM Rome | 1 transfer | |
![]() | 1:38 PM Santhià station | 5h52 | 7:30 PM Rome | 1 transfer | |
![]() | 2:38 PM Santhià station | 5h57 | 8:35 PM Rome | 1 transfer | |
![]() | 4:38 PM Santhià station | 5h41 | 10:19 PM Rome | 1 transfer | |
![]() | 7:04 PM Santhià station | 5h15 | 12:19 AM Rome | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Santhià station to Rome run on average 22 times per day, taking around 5h 49m. Cheap train tickets for this journey start at $44 (€35) but you can travel from only $37 (€30) by bus.
The earliest train runs at 12:21, the last at 18:38. The fastest train covers the 321 miles (518 km) distance in 9h 2m.
Distance 321 miles (518 km) |
Average train duration 5h 49m |
Cheapest ticket price $44 (€35) |
Trains per day 22 |
Fastest train 9h 2m |
First train 12:21 PM |
Last train 6:38 PM |
Cheapest Month Jun |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Tue |
Least Busy Day Tue |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
A vast complex of papal collections including classical sculpture, Renaissance masterpieces, the Raphael Rooms, and access to the Sistine Chapel. One of Rome’s most important art visits and often best
A superb villa museum with Bernini sculptures and paintings by Caravaggio, Raphael, and Titian. Timed entry is limited, making advance booking especially important.
The world’s oldest public museums, displaying Roman bronzes, ancient inscriptions, imperial sculpture, and excellent views over the Roman Forum from Capitoline Hill.
A grand baroque square with Bernini’s Fountain of the Four Rivers, elegant facades, and constant street life. One of Rome’s classic strolling areas.
A lively neighborhood of narrow lanes, ivy-covered buildings, and popular evening atmosphere. Very popular for wandering and photography, especially after sunset.
A famous monumental staircase linking Piazza di Spagna with Trinità dei Monti. A classic meeting point and one of the city’s most photographed urban scenes.
A classic Roman pasta made with pecorino romano and black pepper. It is one of the city’s most iconic dishes for its simplicity and bold flavor.
Traditional Roman pasta with guanciale, egg yolk, pecorino romano, and black pepper. It is a defining dish of Rome and is traditionally made without cream.
A beloved pasta sauce of tomato, guanciale, and pecorino romano, usually served with bucatini. It is a cornerstone of Roman trattoria cooking.
Rome’s best-known luxury dining destination, offering fine dining, panoramic views, and an acclaimed tasting-menu experience by Heinz Beck.
A historic restaurant near the Pantheon celebrated for careful Roman cooking, including gricia, oxtail, and seasonal specialties, in a polished traditional space.
A famous central Rome dining room and delicatessen known for Roman pasta, cured meats, cheeses, and an exceptional wine list in a lively upscale setting.
Moderate by Western Europe standards: sights and central hotels cost more, while casual dining and transit stay reasonable.
Service is often included or covered by a coperto. Tipping is not mandatory; round up or leave EUR 1-2 at cafes, 5-10% for great restaurant service, and round up taxis.
Official public transport app
Rome Termini -> Piazza Venezia, Rome
Find answers to the most common questions about traveling from Santhià station to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

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