The cheapest and fastest trains from Santa Ana to Madrid
Cheapest price
$26
Average price
$26
Fastest journey
3 h 22 m
Average duration
3 h 22 m
Trains per day
1
Distance
231 km
The best way to find a cheap train ticket from Santa Ana to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Ana to Madrid will cost around $26 if you buy it on the day, but the cheapest tickets can be found for only $26.
Of the 1 trains that leave Santa Ana for Madrid on Thu, Dec 25, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Dec 25 the direct trains cover the 231 km distance in an average of 3 h 22 m but if you time it right, some trains will get you there in just 3 h 22 m .
On Thu, Dec 25 the slowest trains will take 3 h 22 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and train for Santa Ana to Madrid
Omio recommends booking the train as it is the most popular option from Santa Ana to Madrid among Omio's users. If you are prioritising price take the bus with prices starting from €31. For those with little time consider booking a bus which can get you there in 3h 41m. The ticket price range depends on the travel mode: a bus costs an average of €31, and a train costs an average of €21.
Distance: 143 miles (231 km)
Compare train with
Most popular Train | Bus |
|---|---|
€41 Average price | €33 Average price Cheapest |
4h 38m Average total duration 4h 8m Onboard + 30m Additional time* | 4h 11m Average total duration Fastest 3h 41m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Santa Ana to Madrid train times
The table below shows live departures for Santa Ana to Madrid trains for today, Wednesday, December 24. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:03 PM Santa Ana | 3h15 | 8:18 PM Madrid | 0 transfersDirect | |
| Thursday, December 25 | |||||
![]() | 5:24 AM Santa Ana | 3h22 | 8:46 AM Madrid | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Ana to Madrid by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 25
Dec 26
Dec 27
Dec 28
Dec 29
Dec 30
Dec 31
Why should you book Santa Ana to Madrid trains with Omio?
Renfe operates all train services from Santa Ana to Madrid. Omio is the only official third party seller for Renfe tickets.
Why book with Omio vs Renfe?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Renfe with all available travel options, which are bus and train to ensure you get the best deal for traveling from Santa Ana to Madrid.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Renfe tickets can only be bought on Omio or Renfe's website as Omio is the only official third party seller for Renfe tickets. Trainline, RailEurope, and Rail.Ninja do not sell Renfe tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Santa Ana to Madrid.
Journey information
Overview: Train from Santa Ana to Madrid
Trains from Santa Ana to Madrid run on average 4 times per day, taking around 4h 8m. Cheap train tickets for this journey start at $26 (€21) if you book in advance.
There are 4 trains per day. The earliest train runs at 06:09, the last at 19:08. The fastest train covers the 143 miles (231 km) distance in 3h 14m.
Distance 143 miles (231 km) |
Average train duration 4h 8m |
Cheapest ticket price $26 (€21) |
Trains per day 4 |
Direct trains 4 |
Fastest train 3h 14m |
First train 06:09 |
Last train 19:08 |
Train companies: Renfe from Santa Ana to Madrid trainsRenfe trains will get you between Santa Ana and Madrid from $26 (€21). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Renfe
FAQs: Trains from Santa Ana to Madrid
Find answers to the most common questions about traveling from Santa Ana to Madrid by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Santa Ana to Madrid
- Mon - Sun: 10:00 - 20:00
- Free WiFi in the station and on all Renfe trains.
- Open daily from 05:30 to 22:00.
- Passion Food
- La Barrila
- Enrique Tomás
- Pic Nic
- Foodissimo!
- PureGusto
- Burger King
- Wheelchair parking, adapted elevators, adapted platforms, lobby shopping area.
- 60 Balconies Urban Stay
- Only YOU Hotel Atocha
- SLEEP’N Atocha
- Mon - Sun: 10:00 - 20:00
- On the ground floor of the main concourse.
- Metro lines: 1
- Bus lines: 10, 14, 24, 26, 32, 37, 54, 57, 59, 85, 86, 102, 121, 203
- Train lines: C1, C2, C3, C4, C5, C7, C8, C10
More options for your journey from Santa Ana to Madrid
Here are some other resources that might have the information you need
