Travel Information
Compare bus and train for Santa Ana to Madrid
Omio recommends booking the train as it is the most popular option from Santa Ana to Madrid among Omio's users. If you are prioritising price take the train with prices starting from €19. For those with little time consider booking a flight which can get you there in 1h 18m. The ticket price range depends on the travel mode: a train costs an average of €19, and a flight costs an average of €53.
Distance: 143 miles (231 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
€29 Average price Cheapest | €67 Average price | €34 Average price |
4h 38m Average total duration 4h 8m Onboard + 30m Additional time* | 4h 18m Average total duration Fastest 1h 18m Onboard + 3h 0m Additional time* | 4h 10m Average total duration 3h 40m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Santa Ana to Madrid by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Santa Ana to Madrid trains with Omio?
Why book with Omio vs Renfe?
- Compare with other providers: On Omio, you can not only buy tickets for Renfe, but also compare tickets for the likes of to find the best option for your trip from Santa Ana to Madrid.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Renfe with all available travel options, which are bus and train to ensure you get the best deal for traveling from Santa Ana to Madrid.
Why book with Omio over Rome2rio or Raileurope?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Santa Ana to Madrid.
Journey information
Overview: Train from Santa Ana to Madrid
Trains from Santa Ana to Madrid run on average 5 times per day, taking around 4h 8m. Cheap train tickets for this journey start at $24 (€19) if you book in advance.
There are 5 trains per day. The earliest train runs at 06:09, the last at 19:08. The fastest train covers the 143 miles (231 km) distance in 3h 11m.
Distance 143 miles (231 km) |
Average train duration 4h 8m |
Cheapest ticket price $24 (€19) |
Trains per day 5 |
Direct trains 5 |
Fastest train 3h 11m |
First train 06:09 |
Last train 19:08 |
Train companies: Renfe from Santa Ana to Madrid trainsRenfe trains will get you between Santa Ana and Madrid from $24 (€19). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Renfe
FAQs: Trains from Santa Ana to Madrid
Find answers to the most common questions about traveling from Santa Ana to Madrid by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Santa Ana to Madrid
- Mon - Sun: 10:00 - 20:00
- Free WiFi in the station and on all Renfe trains.
- Open daily from 05:30 to 22:00.
- Passion Food
- La Barrila
- Enrique Tomás
- Pic Nic
- Foodissimo!
- PureGusto
- Burger King
- Wheelchair parking, adapted elevators, adapted platforms, lobby shopping area.
- 60 Balconies Urban Stay
- Only YOU Hotel Atocha
- SLEEP’N Atocha
- Mon - Sun: 10:00 - 20:00
- On the ground floor of the main concourse.
- Metro lines: 1
- Bus lines: 10, 14, 24, 26, 32, 37, 54, 57, 59, 85, 86, 102, 121, 203
- Train lines: C1, C2, C3, C4, C5, C7, C8, C10
More options for your journey from Santa Ana to Madrid
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