The cheapest and fastest trains from Rome Ostiense to Milan Centrale
- Cheapest price on Nov 04
- $56
- Average ticket price on Nov 04
- $106
- Fastest journey on Nov 04
- 3 h 31 m
- Average journey duration on Nov 04
- 3 h 36 m
- Trains on Nov 04
- 41
- Distance
- 481 km
The best way to find a cheap train ticket from Rome Ostiense to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome Ostiense to Milan Centrale will cost around $106 if you buy it on the day, but the cheapest tickets can be found for only $56.
It's difficult to get from Rome Ostiense to Milan Centrale without transferring at least once.
Regionale Veloce 4134 · Regionale 22962:23 PM 8h59 Rome Ostiense 11:22 PM Milan Centrale $56 1 One-way 1 transfer
Regionale Veloce 4131 · Regionale Veloce 4156+
Intercity 5963:37 PM 7h40 Rome Ostiense 11:17 PM Milan Centrale $69 1 One-way 2 transfers
Regionale 20345+
Intercity 59012:07 PM 7h18 Rome Ostiense 7:25 PM Milan Centrale $75 1 One-way 1 transfer
Regionale 20771+
Intercity 5963:16 PM 8h01 Rome Ostiense 11:17 PM Milan Centrale $75 1 One-way 1 transfer
Regionale 4500+
Intercity 6841:23 PM 8h37 Rome Ostiense 10:00 PM Milan Centrale $77 1 One-way 1 transfer
Regionale 12579+
FRECCIAROSSA 96208:53 AM 3h31 Rome Ostiense 12:24 PM Milan Centrale $115 1 One-way 1 transfer
Regionale 12535+
FRECCIAROSSA 96229:23 AM 3h35 Rome Ostiense 12:58 PM Milan Centrale $115 1 One-way 1 transfer
Regionale 12507+
FRECCIAROSSA 96127:22 AM 3h36 Rome Ostiense 10:58 AM Milan Centrale $115 1 One-way 1 transfer
Regionale 12587+
FRECCIAROSSA 96626:23 PM 3h37 Rome Ostiense 10:00 PM Milan Centrale $115 1 One-way 1 transfer
Regionale 12575+
FRECCIAROSSA 96167:52 AM 3h43 Rome Ostiense 11:35 AM Milan Centrale $115 1 One-way 1 transfer
Journey information
Overview: Train from Rome Ostiense to Milan Centrale
Trains from Rome Ostiense to Milan Centrale run on average 34 times per day, taking around 4h 45m. Cheap train tickets for this journey start at $2 if you book in advance.
There are 1 trains per day. The earliest train runs at 09:41, the last at 17:07. The fastest train covers the 298 miles (481 km) distance in 3h 9m.
Plan this route
Journey facts
- Distance298 miles (481 km)
- Average train duration4h 45m
- Cheapest ticket price$2
- Trains per day34
- Direct trains1
- Fastest train3h 9m
- First train9:41 AM
- Last train5:07 PM
- Cheapest MonthJun
- Cheapest DayWed
- High SeasonJul - Sep
- Low SeasonOct - Dec
- Busiest DaySat
- Least Busy DayThu
- Best time to book14 days
Understand & plan this route
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Frequently asked questions about your Rome Ostiense to Milan Centrale trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Rome Ostiense to Milan Centrale.
Live departures
Rome Ostiense to Milan Centrale train times
The table below shows live departures for Rome Ostiense to Milan Centrale trains for today, Tuesday, November 3. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 20555+ FRECCIAROSSA 9512 | 6:46 AM Rome Ostiense | 4h04 | 10:50 AM Milan Centrale | 1 transfer | |
Regionale 12507+ FRECCIAROSSA 9612 | 7:22 AM Rome Ostiense | 3h36 | 10:58 AM Milan Centrale | 1 transfer | |
Regionale 12575+ FRECCIAROSSA 9616 | 7:52 AM Rome Ostiense | 3h43 | 11:35 AM Milan Centrale | 1 transfer | |
Regionale 12513+ FRECCIAROSSA 9618 | 8:08 AM Rome Ostiense | 3h50 | 11:58 AM Milan Centrale | 1 transfer | |
Regionale 12579+ FRECCIAROSSA 9620 | 8:53 AM Rome Ostiense | 3h31 | 12:24 PM Milan Centrale | 1 transfer | |
Regionale 12535+ FRECCIAROSSA 9622 | 9:23 AM Rome Ostiense | 3h35 | 12:58 PM Milan Centrale | 1 transfer | |
Regionale Veloce 4125+ Intercity 588 · Intercity 608 | 9:37 AM Rome Ostiense | 8h08 | 5:45 PM Milan Centrale | 2 transfers | |
Regionale Veloce 4125+ FRECCIAROSSA 9624 | 9:37 AM Rome Ostiense | 3h58 | 1:35 PM Milan Centrale | 1 transfer | |
Regionale 12523+ FRECCIAROSSA 9626 | 10:07 AM Rome Ostiense | 3h51 | 1:58 PM Milan Centrale | 1 transfer | |
Intercity 510 · Intercity 635 | 10:07 AM Rome Ostiense | 8h53 | 7:00 PM Milan Centrale | 1 transfer | |
Regionale 20615+ FRECCIAROSSA 9416 · FRECCIAROSSA 8814 | 10:16 AM Rome Ostiense | 4h09 | 2:25 PM Milan Centrale | 2 transfers | |
Regionale Veloce 4130+ Intercity 510 · Intercity 635 | 10:23 AM Rome Ostiense | 8h37 | 7:00 PM Milan Centrale | 2 transfers | |
Regionale 12781+ FRECCIAROSSA 9628 | 10:39 AM Rome Ostiense | 3h56 | 2:35 PM Milan Centrale | 1 transfer | |
Regionale 20481+ FRECCIAROSSA 9514 | 10:46 AM Rome Ostiense | 4h04 | 2:50 PM Milan Centrale | 1 transfer | |
Regionale 12531+ FRECCIAROSSA 9630 | 11:07 AM Rome Ostiense | 3h51 | 2:58 PM Milan Centrale | 1 transfer | |
Regionale 12583+ FRECCIAROSSA 9632 | 11:51 AM Rome Ostiense | 3h44 | 3:35 PM Milan Centrale | 1 transfer | |
Regionale 20345+ Intercity 590 | 12:07 PM Rome Ostiense | 7h18 | 7:25 PM Milan Centrale | 1 transfer | |
Regionale 12539+ FRECCIAROSSA 9636 | 12:39 PM Rome Ostiense | 3h51 | 4:30 PM Milan Centrale | 1 transfer | |
Regionale 12541+ FRECCIAROSSA 9638 | 1:07 PM Rome Ostiense | 3h51 | 4:58 PM Milan Centrale | 1 transfer | |
Regionale 4500+ Intercity 684 | 1:23 PM Rome Ostiense | 8h37 | 10:00 PM Milan Centrale | 1 transfer | |
Regionale 12543+ FRECCIAROSSA 9640 | 1:39 PM Rome Ostiense | 3h51 | 5:30 PM Milan Centrale | 1 transfer | |
Regionale 20657+ FRECCIAROSSA 9540 | 1:46 PM Rome Ostiense | 4h04 | 5:50 PM Milan Centrale | 1 transfer | |
Regionale 12663+ FRECCIAROSSA 9642 | 2:07 PM Rome Ostiense | 3h51 | 5:58 PM Milan Centrale | 1 transfer | |
Regionale Veloce 4134 · Regionale 2296 | 2:23 PM Rome Ostiense | 8h59 | 11:22 PM Milan Centrale | 1 transfer | |
Regionale 12547+ FRECCIAROSSA 9644 | 2:39 PM Rome Ostiense | 3h51 | 6:30 PM Milan Centrale | 1 transfer | |
Regionale 12549+ FRECCIAROSSA 9646 | 3:07 PM Rome Ostiense | 3h53 | 7:00 PM Milan Centrale | 1 transfer | |
Regionale 20771+ Intercity 596 | 3:16 PM Rome Ostiense | 8h01 | 11:17 PM Milan Centrale | 1 transfer | |
Regionale Veloce 4131 · Regionale Veloce 4156+ Intercity 596 | 3:37 PM Rome Ostiense | 7h40 | 11:17 PM Milan Centrale | 2 transfers | |
Regionale Veloce 4131+ FRECCIAROSSA 9648 | 3:37 PM Rome Ostiense | 3h47 | 7:24 PM Milan Centrale | 1 transfer | |
Regionale 20677+ FRECCIAROSSA 9588 | 3:46 PM Rome Ostiense | 4h04 | 7:50 PM Milan Centrale | 1 transfer | |
Intercity 518+ Regionale Veloce 3047 | 4:07 PM Rome Ostiense | 7h32 | 11:39 PM Milan Centrale | 1 transfer | |
Regionale 12551+ FRECCIAROSSA 9650 | 4:07 PM Rome Ostiense | 3h51 | 7:58 PM Milan Centrale | 1 transfer | |
Regionale 12585+ FRECCIAROSSA 9652 | 4:40 PM Rome Ostiense | 3h50 | 8:30 PM Milan Centrale | 1 transfer | |
Regionale 12553+ FRECCIAROSSA 9658 | 5:07 PM Rome Ostiense | 3h53 | 9:00 PM Milan Centrale | 1 transfer | |
Regionale 12587+ FRECCIAROSSA 9662 | 6:23 PM Rome Ostiense | 3h37 | 10:00 PM Milan Centrale | 1 transfer | |
Regionale 20715+ FRECCIAROSSA 9560 | 6:46 PM Rome Ostiense | 4h04 | 10:50 PM Milan Centrale | 1 transfer | |
Regionale 12573+ FRECCIAROSSA 9668 | 7:07 PM Rome Ostiense | 3h53 | 11:00 PM Milan Centrale | 1 transfer | |
Regionale Veloce 4135+ FRECCIAROSSA 9592 | 7:37 PM Rome Ostiense | 4h13 | 11:50 PM Milan Centrale | 1 transfer | |
| Wednesday, November 4 | |||||
Intercity 745+ InterCityNotte 794 | 6:06 AM Rome Ostiense | 8h54 | 3:00 PM Milan Centrale | 1 transfer | |
Regionale 12503+ FRECCIAROSSA 9608 | 6:13 AM Rome Ostiense | 3h47 | 10:00 AM Milan Centrale | 1 transfer | |
Regionale 4501+ FRECCIAROSSA 9610 | 6:34 AM Rome Ostiense | 4h01 | 10:35 AM Milan Centrale | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Why should you book Rome Ostiense to Milan Centrale trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Intercity, Intercity Notte or Regionale to find the best option for your trip from Rome Ostiense to Milan Centrale.
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- Compare all your options: Omio allows you to compare Italo with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome Ostiense to Milan Centrale.
Train companies
Train companies from Rome Ostiense to Milan Centrale
Trains from Rome Ostiense to Milan Centrale with Frecciarossa, Italo, and Intercity. Night trains available on this route with Intercity Notte. High-speed trains available on this route with Frecciarossa, Italo, and Frecciabianca. Regional trains available on this route with Regionale. Use the details below to compare onboard facilities.
Frecciarossa
Italo
Intercity
Intercity Notte
Regionale
Frecciabianca
Companies, tickets, and onboard amenities between Rome Ostiense and Milan Centrale
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
FAQs: Trains from Rome Ostiense to Milan Centrale
Find answers to the most common questions about traveling from Rome Ostiense to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Rome Ostiense to Milan Centrale
Most Rome Ostiense to Milan Centrale trains use the Roma Termini to Milano Centrale station pair. Use this guide to compare Rome Ostiense and Milan Centrale train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Getting to Roma Ostiense from Rome city centre
Roma Ostiense is 2 km from Rome city centre. Public transport options include:
Roma Ostiense train station facilities and services
Roma Ostiense has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Ramen Bar Akira, Eataly Roma
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Roma Ostiense. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Roma Ostiense. Lost and found is available at the station.
Parking, taxis and toilets
Available at Roma Ostiense: Parking, Taxis, WC.
Bike and car services
Available at Roma Ostiense: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Roma Ostiense: Elevators, ramps, restrooms.
Shops, hotels and contact
Nearby hotels include Hotel Abitart, Hotel San Anselmo, Hotel Villa San Pio.
Getting to Milano Centrale from Milan city centre
Milano Centrale is 2 km from Milan city centre. Public transport options include:
Milano Centrale train station facilities and services
Milano Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: Venchi, Panzera Coffee, Burger King, Bar Motta, Caffè Napoli, VyTA Boulangerie, Spontini, Starbucks, Dispensa Emilia, McDonald's, & many more
Wi-Fi and ATMs
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
Tickets and information
The ticket office is open Mon - Sun: 05:50 - 22:20. Information desks are located next to the ticket office on the ground floor in the shopping gallery.
Luggage and lost property
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
Parking, taxis and toilets
Available at Milano Centrale: Parking, Taxis, WC.
Bike and car services
Available at Milano Centrale: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Milano Centrale: Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
Shops, hotels and contact
Nearby hotels include Glam Hotel Milano, NYX MIlan, iQ Hotel Milano.

