Travel Information between Palermo and Syracuse
| 126 miles (203 km) | |
| Bus or train | |
| $17 - $22 | |
| Bus • $17 (€15) • 3 h 15 min | |
| Bus • $17 (€15) • 3 h 15 min | |
| Interbus S. P. A. Or Regionale |
Travel 126 miles (203 km) by bus or train between Palermo and Syracuse. The most popular travel companies which serve this journey are Interbus S. P. A. Or Regionale among others. Travelers can even take a direct bus or train from Palermo to Syracuse.
Travel optionsfrom Palermo to Syracuse
How to get from Palermo to Syracuse by train, bus or flight.
Our recommendation
The best way to travel from Palermo to Syracuse is by taking a train because it’s the best combination of price and speed.
Regionale Veloce 5508 · Regionale Veloce 5391Cheapest
Regionale Veloce 5508 · Regionale Veloce 5391Fastest
Regionale Veloce 5520 · Regionale 12989Other options
Regionale 5506 · Regionale 5507
Regionale Veloce 5510 · Regionale 5379
Regionale Veloce 5512 · Regionale Veloce 5397
FlixBus · FlixBusFind all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Palermo to Syracuse
Travel to Syracuse easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Palermo to Syracuse.

You can get to Syracuse from Palermo 2 different ways: bus or train.
The cheapest way to go to Syracuse from Palermo is by taking a bus, which costs on average $17 (€15).
This is compared to other ways of getting from Palermo to Syracuse:
Taking a bus costs $5 (€5) less than taking a train, which costs on average $22 (€20) for the same trip.
The fastest way from Palermo to Syracuse is by bus with an average journey time of 3 h 15 min.
There are alternative travel options to Syracuse that take longer:
Train takes 4 h 29 min on average.
Syracuse is approximately 126 miles (203 km) away from Palermo.
The average frequency per day from Palermo to Syracuse is:
However, we recommend checking specific travel dates for your trip from Palermo to Syracuse as scheduled services by bus or train can vary by season or day of the week.
These are the most popular departure and arrival points when traveling from Palermo to Syracuse:
The following travel companies offer services from Palermo to Syracuse:
- Travel with Interbus S. P. A. To go to Syracuse by bus. For a good deal on tickets, you can find Interbus S. P. A. Palermo to Syracuse tickets on Omio for $17 (€15).
- Travel with Regionale or Intercity for trains to Syracuse. If you’re looking for a good deal on tickets, check for Regionale Palermo to Syracuse tickets on Omio for $22 (€20).
Yes, there are direct routes from Palermo to Syracuse with the following travel companies:
- You can book a direct bus with Interbus S. P. A.
- You can travel directly by train with.
Direct services to Syracuse tend to save you time and add more convenience as you won't need to transfer at another stop in between, so it's worth paying attention to before booking tickets for your route.
Travelling from Palermo to Syracuse: related information
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