Travel Information
Compare bus and train for Palermo to Syracuse
Omio recommends booking the bus as it is the most popular option from Palermo to Syracuse among Omio's users. If you are prioritising price take the train with prices starting from $25. For those with little time consider booking a bus which can get you there in 4h 10m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a train costs an average of $25, and a bus costs an average of $18.
Distance: 126 miles (204 km)
Compare bus with
Most popular Bus | Train |
|---|---|
$33 Average price | $26 Average price Cheapest |
4h 40m Average total duration Fastest 4h 10m Onboard + 30m Additional time* | 5h 30m Average total duration 5h 0m Onboard + 30m Additional time* |
0.2 - 0.5kg CO2 emissions | 0.1 - 0.2kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Palermo to Syracuse
How to get from Palermo to Syracuse by train, bus or flight.
Our recommendation
The best way to travel from Palermo to Syracuse is by taking a train because it’s the best combination of price and speed.
Regionale Veloce 5508 · Regionale Veloce 53919:28 AM4h37Palermo Centrale2:05 PMSyracuse station$251One-way1 transfer
Cheapest
Regionale Veloce 5508 · Regionale Veloce 53919:28 AM4h37Palermo Centrale2:05 PMSyracuse station$251One-way1 transfer
Fastest
Regionale Veloce 5520 · Regionale 129895:28 PM4h10Palermo Centrale9:38 PMSyracuse station$251One-way1 transfer
Other options
Regionale Veloce 5506 · Regionale 55077:28 AM4h43Palermo Centrale12:11 PMSyracuse station$251One-way1 transfer
Regionale Veloce 5510 · Regionale 53791:28 PM4h38Palermo Centrale6:06 PMSyracuse station$251One-way1 transfer
Regionale Veloce 5512 · Regionale Veloce 53973:28 PM4h32Palermo Centrale8:00 PMSyracuse station$251One-way1 transfer
FlixBus · FlixBus3:25 PM5h15Palermo, Via Tommaso Fazello (Terminal Bus)8:40 PMSyracuse, Corso Umberto I$271One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Palermo to Syracuse
Travel to Syracuse easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Palermo to Syracuse.

This is compared to other travel options from Palermo to Syracuse:
A bus is $7 (€6) less than a train for this route with tickets for a train from Palermo to Syracuse costing on average $25 (€20).
Other travel options to Syracuse take longer:
Train takes on average 3h 59m.
- Around 9 trains per day.
- Around 5 buses per day.
However, we recommend checking specific travel dates for your route between Palermo and Syracuse as scheduled services by bus and train can vary by season or day of the week.
- Trains mostly depart from Palermo Centrale and arrive in Syracuse station.
- Buses mostly depart from Palermo, Via Tommaso Fazello (Terminal Bus) and arrive in Syracuse, Corso Umberto I.
- Travel with Regionale, Intercity to go to Syracuse by train.
- Travel with Interbus S.p.A., Alibus, Infobus, FlixBus, BlaBlaCar to go to Syracuse by bus.
- 3 direct buses per day with Interbus S.p.A., BlaBlaCar.
Travelling from Palermo to Syracuse: related information
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