The cheapest and fastest trains from Milan Centrale to Brindisi station
Cheapest price
$90
Average price
$129
Fastest journey
7 h 54 m
Average duration
10 h 1 m
Trains per day
5
Distance
891 km
The best way to find a cheap train ticket from Milan Centrale to Brindisi station is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Brindisi station will cost around $129 if you buy it on the day, but the cheapest tickets can be found for only $90.
Of the 5 trains that leave Milan Centrale for Brindisi station on Fri, Nov 07, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct trains cover the 891 km distance in an average of 10 h 1 m but if you time it right, some trains will get you there in just 7 h 54 m .
On Fri, Nov 07 the slowest trains will take 11 h 8 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare train, bus, and flight for Milan Centrale to Brindisi station
Omio recommends booking the train as it is the most popular option from Milan Centrale to Brindisi station among Omio's users. If you are prioritising price take the bus with prices starting from €15. For those with little time consider booking a flight which can get you there in 1h 41m. The ticket price range depends on the travel mode: a bus costs an average of €15, and a flight costs an average of €28.
Distance: 553 miles (891 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€80 Average price | €39 Average price Cheapest | €95 Average price |
11h 10m Average total duration 10h 40m Onboard + 30m Additional time* | 15h 30m Average total duration 15h 0m Onboard + 30m Additional time* | 4h 41m Average total duration Fastest 1h 41m Onboard + 3h 0m Additional time* |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Milan Centrale to Brindisi station train times
The table below shows live departures for Milan Centrale to Brindisi station trains for tomorrow, Friday, November 7. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:15 AM Milan Centrale | 11h08 | 8:23 PM Brindisi station | 0 transfersDirect | |
![]() | 11:35 AM Milan Centrale | 7h54 | 7:29 PM Brindisi station | 0 transfersDirect | |
![]() | 7:15 PM Milan Centrale | 11h08 | 6:23 AM Brindisi station | 0 transfersDirect | |
![]() | 7:50 PM Milan Centrale | 11h15 | 7:05 AM Brindisi station | 0 transfersDirect | |
![]() | 8:45 PM Milan Centrale | 8h57 | 5:42 AM Brindisi station | 0 transfersDirect |
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Brindisi station by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Train from Milan Centrale to Brindisi station
Trains from Milan Centrale to Brindisi station run on average 14 times per day, taking around 10h 40m. Cheap train tickets for this journey start at $58 (€47) but you can travel from only $18 (€15) by bus.
There are 7 trains per day. The earliest train runs at 03:10, the last at 21:45. The fastest train covers the 553 miles (891 km) distance in 7h 54m.
Distance 553 miles (891 km) |
Average train duration 10h 40m |
Cheapest ticket price $58 (€47) |
Trains per day 14 |
Direct trains 7 |
Fastest train 7h 54m |
First train 03:10 |
Last train 21:45 |
Train companies: Frecciarossa, Intercity Notte, Intercity, Italo from Milan Centrale to Brindisi station trainsFrecciarossa, Intercity Notte, Intercity, Italo trains will get you between Milan Centrale and Brindisi station from $18 (€15). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Intercity Notte
Intercity
Italo
FAQs: Trains from Milan Centrale to Brindisi station
Find answers to the most common questions about traveling from Milan Centrale to Brindisi station by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brindisi station, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Milan Centrale to Brindisi station
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 1:00 a.m. Access is available via Piazza Crispi.
- Ristorante La Locanda del Porto
- McDonald's Brindisi
- Outside the main entrance.
- €1
- Palazzo Virgilio Hotel
- Hotel Orientale
- Grande Albergo Internazionale
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to regional and long-distance destinations
- Bus: Several lines available
- Taxi services available
Most popular train connections from Milan Centrale
More options for your journey from Milan Centrale to Brindisi station
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