The cheapest and fastest trains from Milan Centrale to Frankfurt (Main) Hbf
Cheapest price
$209
Average price
$209
Fastest journey
7 h 58 m
Average duration
7 h 58 m
Trains per day
1
Distance
515 km
The best way to find a cheap train ticket from Milan Centrale to Frankfurt (Main) Hbf is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Frankfurt (Main) Hbf will cost around $209 if you buy it on the day, but the cheapest tickets can be found for only $209.
It's difficult to get from Milan Centrale to Frankfurt (Main) Hbf without transferring at least once.
EuroCity 60+
ICE 278
EuroCity 60+
ICE 278Travel Information
Compare train, bus, and flight for Milan Centrale to Frankfurt (Main) Hbf
Omio recommends booking the train as it is the most popular option from Milan Centrale to Frankfurt (Main) Hbf among Omio's users. If you are prioritising price take the bus with prices starting from €32. For those with little time consider booking a flight which can get you there in 1h 38m. The ticket price range depends on the travel mode: a bus costs an average of €32, and a train costs an average of €60.
Distance: 320 miles (515 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
€149 Average price | €138 Average price | €55 Average price Cheapest |
7h 54m Average total duration 7h 24m Onboard + 30m Additional time* | 4h 38m Average total duration Fastest 1h 38m Onboard + 3h 0m Additional time* | 13h 42m Average total duration 13h 12m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Live departures
Milan Centrale to Frankfurt (Main) Hbf train times
The table below shows live departures for Milan Centrale to Frankfurt (Main) Hbf trains for tomorrow, Saturday, November 29. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
EuroCity 60+ ICE 278 | On time 6:10 AM Milan Centrale | 7h58 | 2:08 PM Frankfurt (Main) Hbf | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Frankfurt (Main) Hbf by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Milan Centrale to Frankfurt (Main) Hbf trains with Omio?
Deutsche Bahn (EC,ICE) as well as Trenitalia and Trenitalia EuroCity offer trains services from Milan Centrale to Frankfurt (Main) Hbf. Omio is an official ticket reseller for all your travel options from Milan Centrale to Frankfurt (Main) Hbf.
Why book with Omio vs Deutsche Bahn (EC,ICE)?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn (EC,ICE), but also compare tickets for the likes of Trenitalia and Trenitalia EuroCity to find the best option for your trip from Milan Centrale to Frankfurt (Main) Hbf.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn (EC,ICE) with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Milan Centrale to Frankfurt (Main) Hbf.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Deutsche Bahn (EC,ICE) tickets can be bought on Deutsche Bahn (EC,ICE)'s website or third party sellers, Omio allows you to compare with the likes of Trenitalia and Trenitalia EuroCity to help you choose the right option for your journey from Milan Centrale to Frankfurt (Main) Hbf.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Milan Centrale to Frankfurt (Main) Hbf.
Journey information
Overview: Train from Milan Centrale to Frankfurt (Main) Hbf
Trains from Milan Centrale to Frankfurt (Main) Hbf run on average 2 times per day, taking around 7h 24m. Cheap train tickets for this journey start at $74 (€60) but you can travel from only $31 (€25) by flight.
There are 1 trains per day. The earliest train runs at 09:10, the last at 10:10. The fastest train covers the 320 miles (515 km) distance in 7h 34m.
Distance 320 miles (515 km) |
Average train duration 7h 24m |
Cheapest ticket price $74 (€60) |
Trains per day 2 |
Direct trains 1 |
Fastest train 7h 34m |
First train 09:10 |
Last train 10:10 |
Train companies: Deutsche Bahn, Trenitalia, Trenitalia EuroCity from Milan Centrale to Frankfurt (Main) Hbf trainsDeutsche Bahn, Trenitalia, Trenitalia EuroCity trains will get you between Milan Centrale and Frankfurt (Main) Hbf from $31 (€25). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Trenitalia
Trenitalia EuroCity
FAQs: Trains from Milan Centrale to Frankfurt (Main) Hbf
Find answers to the most common questions about traveling from Milan Centrale to Frankfurt (Main) Hbf by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Frankfurt (Main) Hbf, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Milan Centrale to Frankfurt (Main) Hbf
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
- Mon - Fri: 07:00 - 21:00
- Sat - Sun: 09:00 - 21:00
- Free Wi-Fi in the station.
- Luggage lockers are located in the main hall.
- asiagourmet
- Burger King
- Ciao Bella
- Coffee Fellows
- Crepes de France Express
- dean&david
- Starbucks
- Uddin's Sky Sportsbar
- McDonald's
- Dunkin Donuts
- & many more
- Step-free access and step markings. Contact the Mobility Service Centre at +49 3065212888 or [email protected].
- Hotel Cristall
- Grand Hotel Empire
- Hotel Carlton
- Located opposite Platforms 12 and 13.
Most popular train connections from Milan Centrale
More options for your journey from Milan Centrale to Frankfurt (Main) Hbf
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