The cheapest and fastest trains from Mestre to Siena
Cheapest price
$44
Average price
$44
Fastest journey
7 h 40 m
Average duration
7 h 40 m
Trains per day
1
Distance
252 km
The best way to find a cheap train ticket from Mestre to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mestre to Siena will cost around $44 if you buy it on the day, but the cheapest tickets can be found for only $44.
Of the 1 trains that leave Mestre for Siena on Fri, Nov 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct trains cover the 252 km distance in an average of 7 h 40 m but if you time it right, some trains will get you there in just 7 h 40 m .
On Fri, Nov 07 the slowest trains will take 7 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and train for Mestre to Siena
Omio recommends booking the bus as it is the most popular option from Mestre to Siena among Omio's users. If you are prioritising price take the bus with prices starting from €7. For those with little time consider booking a bus which can get you there in 4h 18m. The ticket price range depends on the travel mode: a bus costs an average of €7, and a train costs an average of €22.
Distance: 156 miles (252 km)
Compare train with
| Train | Most popular Bus |
|---|---|
€41 Average price | €18 Average price Cheapest |
4h 50m Average total duration 4h 20m Onboard + 30m Additional time* | 4h 48m Average total duration Fastest 4h 18m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Mestre to Siena train times
The table below shows live departures for Mestre to Siena trains for today, Thursday, November 6. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:26 PM Mestre | 10h02 | 5:28 AM Siena | 0 transfersDirect | |
| Friday, November 7 | |||||
![]() | 10:26 AM Mestre | 7h40 | 6:06 PM Siena | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mestre to Siena by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Journey information
Overview: Train from Mestre to Siena
Distance 156 miles (252 km) |
Average train duration 4h 20m |
Cheapest ticket price $27 (€22) |
Trains per day 12 |
Direct trains 1 |
Fastest train 2h 0m |
First train 05:00 |
Last train 21:26 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Mestre to Siena start from as low as $27 (€22) if booked well in advance.
- Standard Fares: Typically, trains cost $51 (€41) depending on the train type and class.
Train companies: Frecciarossa, Regionale from Mestre to Siena trainsFrecciarossa, Regionale trains will get you between Mestre and Siena from $9 (€7). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Regionale
FAQs: Trains from Mestre to Siena
Find answers to the most common questions about traveling from Mestre to Siena by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Mestre to Siena
- 6:00 AM - 10:00 PM Monday - Sunday
- Parking is available near the station, open 24/7.
- Outside the main entrance.
- €1
- Hotel Villa Sara
- Hotel Altieri
- Hotel Ducale
- Located near the main entrance
- The station has a simple layout with two platforms and a small waiting area.
- Bus: Several ACTV lines available
- Tram: Line T1
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available near the station, open 24/7.
- Ristorante Il Vinaio
- Osteria Le Logge
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Italia
- NH Siena
- Hotel Minerva
- Located near the main entrance
- Located near the main entrance
- Free
- The station has a single-level layout with platforms accessible from the main hall.
- Bus: Several local and regional lines available
- Taxi: Available outside the station
Most popular train connections from Mestre
More options for your journey from Mestre to Siena
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