- Must visit
Städel Museum
Major German art museum with masterpieces from Old Masters to modernism; a cornerstone stop on Frankfurt’s Museum Embankment.
Cheapest price
$238
Average price
$238
Fastest journey
11 h 6 m
Average duration
11 h 6 m
Trains per day
1
Distance
673 km
The best way to find a cheap train ticket from La Spezia to Frankfurt am Main is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from La Spezia to Frankfurt am Main will cost around $238 if you buy it on the day, but the cheapest tickets can be found for only $238.
It's difficult to get from La Spezia to Frankfurt am Main without transferring at least once.


Omio recommends booking the bus as it is the most popular option from La Spezia to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from $68. For those with little time consider booking a train which can get you there in 11h 6m. The ticket price range depends on the travel mode: a bus costs an average of $68, and a train costs an average of $238.
Distance: 418 miles (673 km)
| Train | Most popular Bus | Driving |
|---|---|---|
$238 Average price | $86 Average price Cheapest | $177 Average price (fuel + tolls) |
11h 36m Average total duration Fastest 11h 6m Onboard + 30m Additional time* | 14h 12m Average total duration 13h 42m Onboard + 30m Additional time* | 9h 25m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from La Spezia to Frankfurt am Main:
A bus is $152 (€125) less than a train for this route with tickets for a train from La Spezia to Frankfurt am Main costing on average $238 (€196).
Other travel options to Frankfurt am Main take longer:
Train takes on average 11h 6m.
Bus takes on average 13h 42m.
Tickets start at around $238 (€196) compared to roughly $177 (€146) in fuel and tolls — a saving of about $-61.13 (€-50.29). The journey takes 11h 6m versus 9h 25m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for La Spezia to Frankfurt am Main trains for tomorrow, Wednesday, July 22. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:38 AM La Spezia | 11h06 | 6:44 PM Frankfurt am Main | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from La Spezia to Frankfurt am Main run on average 1 times per day, taking around 11h 6m. Cheap train tickets for this journey start at $238 (€196) but you can travel from only $68 (€56) by bus.
The earliest train runs at 01:02, the last at 20:21. The fastest train covers the 418 miles (673 km) distance in 11h 6m.
Distance 418 miles (673 km) |
Average train duration 11h 6m |
Cheapest ticket price $238 (€196) |
Trains per day 1 |
Fastest train 11h 6m |
First train 1:02 AM |
Last train 8:21 PM |
High Season Apr - Jun |
Low Season Jul - Sep |
Discover the best of Frankfurt am Main — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frankfurt am Main trip today.
Major German art museum with masterpieces from Old Masters to modernism; a cornerstone stop on Frankfurt’s Museum Embankment.
Museum in Goethe’s birthplace presenting the writer’s life, era, and manuscripts; essential for literary and cultural history fans.
Large natural history museum with dinosaur skeletons, biodiversity displays, and strong geology exhibits; excellent for all ages.
Rebuilt old town quarter between Römer and cathedral, blending historic layouts with new architecture; ideal for strolling and photos.
Frankfurt’s riverside museum district and promenade, perfect for walking, major museums, and skyline views across the Main.
Large inner-city palm garden with themed greenhouses and landscaped grounds; a relaxing break from museums and shopping.
Green sauce made with seven fresh herbs, usually served with boiled eggs and potatoes. It is a Frankfurt classic with protected regional status.
Pork sausage lightly smoked and traditionally served hot with potato salad, sauerkraut, or bread. It is one of Frankfurt’s signature sausages.
Pressed and cured pork sausage, often sliced and served cold with bread, mustard, and pickles. It is a staple in Frankfurt cider taverns.
Two Michelin-starred dining with creative modern cuisine, extensive wine pairings, and a formal fine dining experience.
Refined restaurant in the old opera house area, known for modern European cuisine, polished service, and an elegant dining room.
Historic apple wine tavern in Sachsenhausen known for Apfelwein, green sauce, and classic Frankfurt dishes in a lively traditional setting.
Moderate for Germany: hotels can be pricey during trade fairs, but dining and public transport are reasonable for most tourists.
Round up or tip about 5-10% in restaurants for good service. Taxis are usually rounded up. Small change is common for cafes.
Find answers to the most common questions about traveling from La Spezia to Frankfurt am Main by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

Most La Spezia to Frankfurt am Main trains use the to Frankfurt (Main) Süd station pair. Use this guide to compare La Spezia and Frankfurt am Main train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Frankfurt (Main) Süd is 1 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt (Main) Süd has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Merals Imbiss, Bootshaus am Eisernen Steg, Freigut, Holbein's
Wi-Fi is available at Frankfurt (Main) Süd. ATMs are available at Frankfurt (Main) Süd.
Ticket office support is available at Frankfurt (Main) Süd. Information desks are available at Frankfurt (Main) Süd.
Luggage storage is available at Frankfurt (Main) Süd. Lost and found is available at the station.
Available at Frankfurt (Main) Süd: Parking, Taxis, WC.
Available at Frankfurt (Main) Süd: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Frankfurt (Main) Süd.
Nearby hotels include Hotel am Berg, Leonardo Royal Hotel Frankfurt, Hotel Ritter, Lindner Main Plaza.
Here are some other resources that might have the information you need