Travel Information
Compare train and bus for St. Louis, MO to Wilmington, DE
Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Wilmington, DE among Omio's users. If you are prioritising price take the bus with prices starting from €135. For those with little time consider booking a flight which can get you there in 11h 50m. The ticket price range depends on the travel mode: a bus costs an average of €135, and a train costs an average of €217.
Distance: 787 miles (1267 km)
Compare train with
| Train | Most popular Bus | Flight |
|---|---|---|
€217 Average price | €135 Average price Cheapest | €211 Average price |
35h 50m Average total duration 35h 20m Onboard + 30m Additional time* | 24h 8m Average total duration 23h 38m Onboard + 30m Additional time* | 14h 50m Average total duration Fastest 11h 50m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets St. Louis, MO to Wilmington, DE by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book St. Louis to Wilmington trains with Omio?
Amtrak operates all train services from St. Louis to Wilmington. Omio is the only official third party seller for Amtrak tickets.
Why book with Omio vs Amtrak?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are train and bus to ensure you get the best deal for traveling from St. Louis to Wilmington.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Amtrak tickets can only be bought on Omio or Amtrak's website as Omio is the only official third party seller for Amtrak tickets. Trainline, RailEurope, and Rail.Ninja do not sell Amtrak tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from St. Louis to Wilmington.
Journey information
Overview: Train from St. Louis, MO to Wilmington, DE
Trains from St. Louis, MO to Wilmington, DE run on average 3 times per day, taking around 35h 20m. Cheap train tickets for this journey start at $271 (€217) but you can travel from only $168 (€135) by bus.
The earliest train runs at 08:10, the last at 13:31. The fastest train covers the 787 miles (1267 km) distance in 35h 20m.
Distance 787 miles (1267 km) |
Average train duration 35h 20m |
Cheapest ticket price $271 (€217) |
Trains per day 3 |
Fastest train 35h 20m |
First train 08:10 |
Last train 13:31 |
Train companies: Amtrak from St. Louis, MO to Wilmington, DE trainsAmtrak trains will get you between St. Louis, MO and Wilmington, DE from $168 (€135). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from St. Louis, MO to Wilmington, DE
Find answers to the most common questions about traveling from St. Louis, MO to Wilmington, DE by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Wilmington, DE, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from St. Louis, MO to Wilmington, DE
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
- 5:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 24/7. Access via Martin Luther King Jr. Blvd.
- Mikimotos Asian Grill & Sushi Bar
- La Fia Bistro
- Outside the main entrance.
- Ramps, restrooms.
- $0.50
- Hotel du Pont
- Sheraton Suites Wilmington Downtown
- Courtyard by Marriott Wilmington Downtown
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-6 for Amtrak and SEPTA services
- Bus: Several DART First State bus lines available
- Amtrak: Northeast Corridor services
- SEPTA: Wilmington/Newark Line
Most popular train connections from St. Louis, MO
More options for your journey from St. Louis, MO to Wilmington, DE
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