- Must visit
Städel Museum
Major German art museum with masterpieces from Old Masters to modernism; a cornerstone stop on Frankfurt’s Museum Embankment.


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Cheapest price
$134
Average price
$159
Fastest journey
16h 15m
Average duration
22h 18m
Buses per day
4
Distance
746 km
Omio recommends booking the flight as it is the most popular option from Florence Santa Maria Novella to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from $63. For those with little time consider booking a flight which can get you there in 2h 16m. The ticket price range depends on the travel mode: a bus costs an average of $63, and a train costs an average of $263.
Distance: 454 miles (731 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$291 Average price | $281 Average price | $96 Average price Cheapest | $107 Average price (fuel + tolls) |
10h 27m Average total duration 9h 57m Onboard + 30m Additional time* | 5h 16m Average total duration Fastest 2h 16m Onboard + 3h 0m Additional time* | 19h 31m Average total duration 19h 1m Onboard + 30m Additional time* | 9h 49m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Florence Santa Maria Novella to Frankfurt am Main:
A bus is $184 (€152) less than a flight for this route with tickets for a flight from Florence Santa Maria Novella to Frankfurt am Main costing on average $281 (€231).
A bus is $195 (€160) less than a train for this route with tickets for a train from Florence Santa Maria Novella to Frankfurt am Main costing on average $291 (€240).
Other travel options to Frankfurt am Main take longer:
Train takes on average 9h 57m.
Bus takes on average 19h 1m.
Tickets start at around $291 (€240) compared to roughly $107 (€88) in fuel and tolls — a saving of about $-184.75 (€-151.86). The journey takes 9h 57m versus 9h 49m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Florence Santa Maria Novella to Frankfurt am Main trains for today, Wednesday, July 15. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:25 AM Florence Santa Maria Novella | 10h19 | 6:44 PM Frankfurt am Main | 1 transfer | |
![]() | 9:10 AM Florence Santa Maria Novella | 9h34 | 6:44 PM Frankfurt am Main | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Florence Santa Maria Novella to Frankfurt am Main run on average 1 times per day, taking around 9h 57m. Cheap train tickets for this journey start at $263 (€216) but you can travel from only $63 (€52) by bus.
The earliest train runs at 08:25, the last at 09:10. The fastest train covers the 454 miles (731 km) distance in 9h 34m.
Distance 454 miles (731 km) |
Average train duration 9h 57m |
Cheapest ticket price $263 (€216) |
Trains per day 1 |
Fastest train 9h 34m |
First train 8:25 AM |
Last train 9:10 AM |
High Season Apr - Jun |
Low Season Jul - Sep |
Discover the best of Frankfurt am Main — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frankfurt am Main trip today.
Major German art museum with masterpieces from Old Masters to modernism; a cornerstone stop on Frankfurt’s Museum Embankment.
Museum in Goethe’s birthplace presenting the writer’s life, era, and manuscripts; essential for literary and cultural history fans.
Large natural history museum with dinosaur skeletons, biodiversity displays, and strong geology exhibits; excellent for all ages.
Rebuilt old town quarter between Römer and cathedral, blending historic layouts with new architecture; ideal for strolling and photos.
Frankfurt’s riverside museum district and promenade, perfect for walking, major museums, and skyline views across the Main.
Large inner-city palm garden with themed greenhouses and landscaped grounds; a relaxing break from museums and shopping.
Green sauce made with seven fresh herbs, usually served with boiled eggs and potatoes. It is a Frankfurt classic with protected regional status.
Pork sausage lightly smoked and traditionally served hot with potato salad, sauerkraut, or bread. It is one of Frankfurt’s signature sausages.
Pressed and cured pork sausage, often sliced and served cold with bread, mustard, and pickles. It is a staple in Frankfurt cider taverns.
Two Michelin-starred dining with creative modern cuisine, extensive wine pairings, and a formal fine dining experience.
Refined restaurant in the old opera house area, known for modern European cuisine, polished service, and an elegant dining room.
Historic apple wine tavern in Sachsenhausen known for Apfelwein, green sauce, and classic Frankfurt dishes in a lively traditional setting.
Moderate for Germany: hotels can be pricey during trade fairs, but dining and public transport are reasonable for most tourists.
Round up or tip about 5-10% in restaurants for good service. Taxis are usually rounded up. Small change is common for cafes.
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Frankfurt am Main by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Frankfurt am Main, this guide helps you travel smarter and with confidence.

Most Florence Santa Maria Novella to Frankfurt am Main trains use the Firenze Campo di Marte to Frankfurt Konstablerwache station pair, with some services arriving at Frankfurt Flughafen Fernbf. Use this guide to compare Florence Santa Maria Novella and Frankfurt am Main train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Frankfurt (Main) Süd is 1 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt (Main) Süd has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Merals Imbiss, Bootshaus am Eisernen Steg, Freigut, Holbein's
Wi-Fi is available at Frankfurt (Main) Süd. ATMs are available at Frankfurt (Main) Süd.
Ticket office support is available at Frankfurt (Main) Süd. Information desks are available at Frankfurt (Main) Süd.
Luggage storage is available at Frankfurt (Main) Süd. Lost and found is available at the station.
Available at Frankfurt (Main) Süd: Parking, Taxis, WC.
Available at Frankfurt (Main) Süd: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Frankfurt (Main) Süd.
Nearby hotels include Hotel am Berg, Leonardo Royal Hotel Frankfurt, Hotel Ritter, Lindner Main Plaza.
Frankfurt Flughafen Fernbf is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt Flughafen Fernbf has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: Restaurant Käfer's, McDonald's, Asia Snack Box
Free. ATMs are available in the train station.
Ticket office support is available at Frankfurt Flughafen Fernbf. Information desks are located in the main hall.
Luggage storage is available at Frankfurt Flughafen Fernbf. Lost and found is available at the station.
Available at Frankfurt Flughafen Fernbf: Parking, Taxis, WC.
Available at Frankfurt Flughafen Fernbf: Bike Parking, Car Rental.
Accessibility facilities are available at Frankfurt Flughafen Fernbf: Elevators, ramps.
Nearby hotels include Sheraton Frankfurt Airport Hotel, Hilton Frankfurt Airport, Hilton Garden Inn Frankfurt Airport.
Frankfurt (Main) West is 3 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt (Main) West has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food options include: Immer Satt, Café Crumble, Café Albatros, Cafe Extrablatt
Wi-Fi is available at Frankfurt (Main) West. ATMs are available at Frankfurt (Main) West.
Ticket office support is available at Frankfurt (Main) West. Information desks are available at Frankfurt (Main) West.
Luggage storage is available at Frankfurt (Main) West. Lost and found is available at the station.
Available at Frankfurt (Main) West: Parking, Taxis, WC.
Available at Frankfurt (Main) West: Bike Parking, Bike Rental, Car Rental.
Accessibility facilities are available at Frankfurt (Main) West.
Nearby hotels include Frankfurt Marriott Hotel, Imperial, Sophien Hotel, Hotel Isha.
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