Clayton, MO to Chicago, IL train with Amtrak

Sat, Nov 08
+ Add return
Amtrak
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Amtrak
Regionale
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1,000+ travel companies
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The cheapest and fastest trains from Clayton, MO to Chicago, IL

Showing times and prices for Nov 08

Cheapest price

$137

Average price

$137

Fastest journey

5 h 41 m

Average duration

6 h 21 m

Trains per day

5

Distance

423 km

Cheap tickets

The best way to find a cheap train ticket from Clayton, MO to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Clayton, MO to Chicago, IL will cost around $137 if you buy it on the day, but the cheapest tickets can be found for only $137.

Fast trains

It's difficult to get from Clayton, MO to Chicago, IL without transferring at least once.

Metro St. Louis
12:49AM8h36
Clayton, MO
09:25AMChicago, IL
$1371One-way
1 transfer
Metro St. Louis
05:59AM5h41
Clayton, MO
11:40AMChicago, IL
$1371One-way
1 transfer
Metro St. Louis
07:39AM6h05
Clayton, MO
01:44PMChicago, IL
$1371One-way
1 transfer
Metro St. Louis
02:19PM5h41
Clayton, MO
08:00PMChicago, IL
$1371One-way
1 transfer
Metro St. Louis
04:59PM5h44
Clayton, MO
10:43PMChicago, IL
$1371One-way
1 transfer

Travel Information

Compare train and bus for Clayton, MO to Chicago, IL

Omio recommends booking the train as it is the most popular option from Clayton, MO to Chicago, IL among Omio's users. If you are prioritising price take the train with prices starting from €112. For those with little time consider booking a train which can get you there in 4h 58m. The ticket price range depends on the travel mode: a train costs an average of €112, and a bus costs an average of €129.

Distance: 262 miles (423 km)

Compare train with

Most popular
Train
Bus

€112

Average price

Cheapest

€129

Average price

5h 28m

Average total duration

Fastest

4h 58m

Onboard

+

30m

Additional time*

9h 6m

Average total duration

8h 36m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Live departures

Clayton, MO to Chicago, IL train times

The table below shows live departures for Clayton, MO to Chicago, IL trains for tomorrow, Saturday, November 8. You can also manually refresh the results below to see updated train journeys.

Last updated at 10:55 PM
ProviderDepartsDurationArrivesTransfers
Tickets
Metro St. Louis12:49 AM Clayton, MO
8h36
9:25 AM Chicago, IL1 transfer
Metro St. Louis5:59 AM Clayton, MO
5h41
11:40 AM Chicago, IL1 transfer
Metro St. Louis7:39 AM Clayton, MO
6h05
1:44 PM Chicago, IL1 transfer
Metro St. Louis2:19 PM Clayton, MO
5h41
8:00 PM Chicago, IL1 transfer
Metro St. Louis4:59 PM Clayton, MO
5h44
10:43 PM Chicago, IL1 transfer

Find all the dates and times for this journey

Compare prices and tickets Clayton, MO to Chicago, IL by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Nov 08
Sun
Nov 09
Mon
Nov 10
Tue
Nov 11
Wed
Nov 12
Thu
Nov 13
Fri
Nov 14

Journey information

Overview: Train from Clayton, MO to Chicago, IL

USAUSA
USAUSA
Icon of train
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
262 miles (423 km)
Average train duration
4h 58m
Cheapest ticket price
$138 (€112)
Trains per day
11
Direct trains
9
Fastest train
5h 41m
First train
00:49
Last train
16:59

Key Takeaways

Train Ticket Prices
  • Budget Options: Train tickets from Clayton, MO to Chicago, IL start from as low as $138 (€112) if booked well in advance.
  • Standard Fares: Typically, trains cost $138 (€112) depending on the train type and class.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Train companies: Amtrak from Clayton, MO to Chicago, IL trainsAmtrak trains will get you between Clayton, MO and Chicago, IL from $138 (€112). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Amtrak

About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
4h 19m
Cheapest Price
$42 (€34)
Amtrak frequency
12 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone

FAQs: Trains from Clayton, MO to Chicago, IL

Find answers to the most common questions about traveling from Clayton, MO to Chicago, IL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

FAQs
To fully experience Chicago, IL, plan for at least 3-4 days to visit key attractions such as Millennium Park, The Art Institute of Chicago, Navy Pier, and explore diverse neighborhoods.
The distance by train from Clayton, MO to Chicago, IL is 262 miles (423 km).
A day trip from Clayton, MO to Chicago, IL is not feasible as the journey takes 5h 41m. Trains run 11 times per day, and the distance is 262 miles (423 km).
The train station in Clayton, MO that goes to Chicago, IL is St. Louis Station, St. Louis, MO, which connects to Chicago Union Station, Chicago, IL.
The train journey from Clayton, MO to Chicago, IL offers scenic views of the Midwest's rolling landscapes, farmland, and small towns, providing a picturesque and relaxing ride.
There is no high speed train available from Clayton, MO to Chicago, IL.
In Chicago, IL, you can explore the Museum of Science and Industry and its interactive exhibits, enjoy the vibrant neighborhoods like Wicker Park and Lincoln Park, take a river cruise to view iconic architecture, and attend a live performance at the historic Chicago Theatre. Visit Lincoln Park Zoo for a free and enjoyable day. For sights, don't miss Millennium Park with its modern art, the renowned Art Institute of Chicago, the entertainment hub of Navy Pier, panoramic views from Willis Tower Skydeck, and the fascinating exhibits at the Field Museum.
The train from Clayton, MO to Chicago, IL takes 5h 41m and runs 11 per day.
Train ticket prices from Clayton, MO to Chicago, IL can vary. The cheapest ticket starts at $138 (€112), while the average price is around $138 (€112).
The cheapest way to get from Clayton, MO to Chicago, IL is by train, with a cost of around $138 (€112).
The last train from Clayton, MO to Chicago, IL leaves at 4:59 PM.
The first train from Clayton, MO to Chicago, IL leaves at 12:49 AM.
Unfortunately, there is no night train available from Clayton, MO to Chicago, IL.
Yes, you can take the train from Clayton, MO to Chicago, IL.
Yes, there is a direct train from Clayton, MO to Chicago, IL. This service operates 9 times per day, provided by Amtrak.

popular train stations

Popular train stations from Clayton, MO to Chicago, IL

Clayton
Chicago
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
LoungeLounge
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Car RentalCar Rental
Information DeskInformation Desk
Luggage CartsLuggage Carts
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • 5:00 AM - 12:00 AM Monday - Sunday
ticketOfficeHours
Distance to city center
3 km
platformCount
Number of platforms
24
Wifi
Wifi
  • Free
Parking
Parking
  • The car park is open 7 days a week from 5:00 a.m. to 12:00 a.m. Departures can be made outside of opening hours. Access via Canal Street.
Dining
Dining
  • The Chicago Firehouse Restaurant
  • Lou Mitchell's
Taxis
Taxis
  • Outside the main entrance.
Accessibility
Accessibility
  • Elevators, ramps, restrooms.
WC
WC
  • $1
Hotel
Hotel
  • The Kimpton Gray Hotel
  • JW Marriott Chicago
  • W Chicago - City Center
Lounge
Lounge
  • Located in the main hall
Lost and Found Office
Lost and Found Office
  • Located in the main hall
Car Rental
Car Rental
  • Avis
  • Budget
  • Enterprise
Information Desk
Information Desk
  • Located in the main hall
Luggage Carts
Luggage Carts
  • Free
Station Plan
  • Hall 1: main entrance, Amtrak services
  • Hall 2: Metra services
  • Hall 3: food court and retail shops
Public transit options for Union Station
  • Bus: Several lines available
  • CTA: Blue Line, Pink Line

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