The cheapest and fastest trains from Cape Girardeau, MO to Chicago, IL
Cheapest price
$37
Average price
$37
Fastest journey
18 h 29 m
Average duration
18 h 29 m
Trains per day
1
Distance
530 km
The best way to find a cheap train ticket from Cape Girardeau, MO to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Cape Girardeau, MO to Chicago, IL will cost around $37 if you buy it on the day, but the cheapest tickets can be found for only $37.
Of the 1 trains that leave Cape Girardeau, MO for Chicago, IL on Wed, Nov 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Nov 05 the direct trains cover the 530 km distance in an average of 18 h 29 m but if you time it right, some trains will get you there in just 18 h 29 m .
On Wed, Nov 05 the slowest trains will take 18 h 29 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train and bus for Cape Girardeau, MO to Chicago, IL
Omio recommends booking the train as it is the most popular option from Cape Girardeau, MO to Chicago, IL among Omio's users. If you are prioritising price take the train with prices starting from €32. For those with little time consider booking a train which can get you there in 5h 37m. The ticket price range depends on the travel mode: a train costs an average of €32, and a bus costs an average of €53.
Distance: 329 miles (530 km)
Compare train with
Most popular Train | Bus |
|---|---|
€40 Average price Cheapest | €53 Average price |
6h 7m Average total duration Fastest 5h 37m Onboard + 30m Additional time* | 9h 5m Average total duration 8h 35m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Live departures
Cape Girardeau, MO to Chicago, IL train times
The table below shows live departures for Cape Girardeau, MO to Chicago, IL trains for today, Tuesday, November 4. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:15 PM Cape Girardeau, MO | 5h30 | 2:45 AM Chicago, IL | 0 transfersDirect | |
| Wednesday, November 5 | |||||
![]() | 8:16 AM Cape Girardeau, MO | 18h29 | 2:45 AM Chicago, IL | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Cape Girardeau, MO to Chicago, IL by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 05
Nov 06
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Journey information
Overview: Train from Cape Girardeau, MO to Chicago, IL
Distance 329 miles (530 km) |
Average train duration 5h 37m |
Cheapest ticket price $39 (€32) |
Trains per day 4 |
Direct trains 3 |
Fastest train 5h 30m |
First train 03:16 |
Last train 20:05 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Cape Girardeau, MO to Chicago, IL start from as low as $39 (€32) if booked well in advance.
- Standard Fares: Typically, trains cost $49 (€40) depending on the train type and class.
Train companies: Amtrak from Cape Girardeau, MO to Chicago, IL trainsAmtrak trains will get you between Cape Girardeau, MO and Chicago, IL from $39 (€32). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Cape Girardeau, MO to Chicago, IL

popular train stations
Popular train stations from Cape Girardeau, MO to Chicago, IL
- 5:00 AM - 12:00 AM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 12:00 a.m. Departures can be made outside of opening hours. Access via Canal Street.
- The Chicago Firehouse Restaurant
- Lou Mitchell's
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $1
- The Kimpton Gray Hotel
- JW Marriott Chicago
- W Chicago - City Center
- Located in the main hall
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, Amtrak services
- Hall 2: Metra services
- Hall 3: food court and retail shops
- Bus: Several lines available
- CTA: Blue Line, Pink Line
More options for your journey from Cape Girardeau, MO to Chicago, IL
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