The cheapest and fastest trains from St. Charles, MO to Chicago, IL
Cheapest price
$59
Average price
$59
Fastest journey
4 h 11 m
Average duration
4 h 11 m
Trains per day
1
Distance
417 km
The best way to find a cheap train ticket from St. Charles, MO to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Charles, MO to Chicago, IL will cost around $59 if you buy it on the day, but the cheapest tickets can be found for only $59.
Of the 1 trains that leave St. Charles, MO for Chicago, IL on Fri, Feb 27, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Feb 27 the direct trains cover the 417 km distance in an average of 4 h 11 m but if you time it right, some trains will get you there in just 4 h 11 m .
On Fri, Feb 27 the slowest trains will take 4 h 11 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for St. Charles, MO to Chicago, IL
Omio recommends booking the train as it is the most popular option from St. Charles, MO to Chicago, IL among Omio's users. If you are prioritising price take the train with prices starting from $27. For those with little time consider booking a flight which can get you there in 1h 32m. The ticket price range depends on the travel mode: a train costs an average of $27, and a flight costs an average of $161.
Distance: 259 miles (417 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$53 Average price Cheapest | $57 Average price | $279 Average price |
4h 55m Average total duration 4h 25m Onboard + 30m Additional time* | 7h 53m Average total duration 7h 23m Onboard + 30m Additional time* | 4h 32m Average total duration Fastest 1h 32m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
St. Charles, MO to Chicago, IL train times
The table below shows live departures for St. Charles, MO to Chicago, IL trains for today, Thursday, February 26. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets | |
|---|---|---|---|---|---|---|
![]() | 11:14 AM St. Charles, MO | 4h11 | 3:25 PM Chicago, IL | 0 transfersDirect | ||
This is the last train of the day. | ||||||
Find all the dates and times for this journey
Compare prices and tickets St. Charles, MO to Chicago, IL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 27
Feb 28
Mar 01
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Mar 05
Journey information
Overview: Train from St. Charles, MO to Chicago, IL
Trains from St. Charles, MO to Chicago, IL run on average 17 times per day, taking around 4h 25m. Cheap train tickets for this journey start at $27 (€22) if you book in advance.
There are 13 trains per day. The earliest train runs at 04:30, the last at 23:45. The fastest train covers the 259 miles (417 km) distance in 4h 11m.
Distance 259 miles (417 km) |
Average train duration 4h 25m |
Cheapest ticket price $27 (€22) |
Trains per day 17 |
Direct trains 13 |
Fastest train 4h 11m |
First train 04:30 |
Last train 23:45 |
Train companies: Amtrak from St. Charles, MO to Chicago, IL trainsAmtrak trains will get you between St. Charles, MO and Chicago, IL from $27 (€22). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from St. Charles, MO to Chicago, IL
Find answers to the most common questions about traveling from St. Charles, MO to Chicago, IL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from St. Charles, MO to Chicago, IL
- 5:00 AM - 12:00 AM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 12:00 a.m. Departures can be made outside of opening hours. Access via Canal Street.
- The Chicago Firehouse Restaurant
- Lou Mitchell's
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $1
- The Kimpton Gray Hotel
- JW Marriott Chicago
- W Chicago - City Center
- Located in the main hall
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, Amtrak services
- Hall 2: Metra services
- Hall 3: food court and retail shops
- Bus: Several lines available
- CTA: Blue Line, Pink Line
More options for your journey from St. Charles, MO to Chicago, IL
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