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Why should you book Santo Domingo to Madrid flights with Omio?
Iberia as well as Air Europa, World2Fly, American Airlines, DELTA and more offer flights services from Santo Domingo to Madrid.
Omio is an official ticket reseller for all your travel options from Santo Domingo to Madrid.
Why book with Omio vs Iberia?
- Compare with other providers: On Omio, you can not only buy tickets for Iberia, but also compare tickets for the likes of Air Europa, World2Fly, American Airlines or DELTA to find the best option for your trip from Santo Domingo to Madrid.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Kayak, Trip or Edreams?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Air Europa, World2Fly, American Airlines or DELTA to find the best option for your trip from Santo Domingo to Madrid.
Airlines: Iberia, Air Europa, World2Fly, American Airlines, DELTA from Santo Domingo to MadridFind the best flights between Santo Domingo to Madrid with Omio's travel partners Iberia, Air Europa, World2Fly, American Airlines, DELTA from $292 (€237). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
World2Fly
About
World2Fly is a Spanish/Portuguese charter and ACMI airline established in 2020 and owned by the Iberostar Group. It commenced operations on June 19, 2021, with hubs at Adolfo Suárez Madrid–Barajas Airport in Spain and Humberto Delgado Airport in Lisbon, Portugal. The airline primarily focuses on long-haul flights to popular tourism destinations, mainly in the Caribbean, including Punta Cana, Cancun, and Havana. World2Fly operates an all-Airbus fleet, including A350s and A330s, and aims to offer a unique onboard experience with a focus on sustainability.
Luggage & cancellation policy
Average Duration
8h 20m
Cheapest Price
$292 (€237)
Luggage included
1 cabin bag (max. 55x40x20 cm) and 1 personal item (max. 40x30x20 cm)
Additional luggage
23kg checked baggage included
Cancellation Policy
Free cancellation within 24 hours of booking if flight is more than 7 days away
Pregnant on board
Pregnant women can fly up to week 36 of pregnancy (week 32 for multiple pregnancies). Medical certificate required from week 28
Unaccompagned minor
we accept UMs from ages 5 to 11. For this age group, it is mandatory to hire the unaccompanied minor service
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
World2Fly offers assistance for passengers with reduced mobility, including wheelchair services and priority boarding. Passengers are advised to request these services in advance to ensure availability.
Pets
Small cats and dogs in a carrier with a combined weight under 22 lbs (10 kg) can travel in the cabin
Entertaiment on board
American Airlines
About
American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.
Luggage & cancellation policy
Average Duration
13h 30m
Cheapest Price
$741 (€601)
American Airlines frequency
1 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item (18 x 14 x 8 inches) included in most fares
Additional luggage
Checked bags fees vary by route. First checked bag typically $30, second $40 on domestic flights
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with fee, refunds subject to fare rules.
Pregnant on board
Passengers can fly up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required within 7 days of departure if within 4 weeks of due date.
Unaccompagned minor
Children ages 5-14 can travel alone using American Airlines Unaccompanied Minor Service. Service fee is $150 each way.
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
American Airlines provides wheelchair assistance and special services for passengers with disabilities. Assistance must be requested at least 48 hours before departure.
Pets
Small dogs and cats allowed in cabin for $125 fee. Must be in approved carrier under seat. Service animals allowed.
Entertaiment on board
Iberia
About
Iberia is the national airline of Spain and a key member of the International Airlines Group (IAG), operating flights throughout Europe and to major global destinations. Its wide range of services makes travel easy and flexible—Economy passengers enjoy affordable fares with comfort, while Business Class travelers can experience premium seating, exclusive lounges, and enhanced dining. From short domestic flights to intercontinental journeys, Iberia combines Spanish hospitality with modern amenities, making it a popular choice worldwide.
Luggage & cancellation policy
Average Duration
8h 10m
Cheapest Price
$499 (€405)
Luggage included
1 cabin bag (40x30x20 cm) and 1 checked bag (158 cm total dimensions) included in most fares except Basic
Additional luggage
Additional bags can be purchased, with prices varying by route and fare type
Cancellation Policy
Basic fares non-refundable, Flexible fares refundable with fee, Business fully refundable
Pregnant on board
Pregnant women can fly up to 36 weeks (single pregnancy) or 32 weeks (multiple pregnancy). Medical certificate required after 28 weeks
Unaccompagned minor
Children aged 5-11 can travel alone using Iberia's unaccompanied minor service. Service is optional for ages 12-17
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Iberia provides assistance for passengers with reduced mobility, including wheelchair assistance and special services for visually or hearing impaired passengers
Pets
Small pets under 8kg in cabin, larger animals in hold. Must be booked in advance
Entertaiment on board
Air Europa
About
Air Europa is Spain’s third most popular airline, offering flights across Europe and to destinations worldwide. For your next trip, you can choose between Economy and Business Class fares.
Luggage & cancellation policy
Average Duration
8h 5m
Cheapest Price
$409 (€332)
Luggage included
1 cabin bag (55x35x25 cm) max 10kg
Additional luggage
23kg checked baggage available for purchase
Cancellation Policy
Refunds available depending on fare type, Basic fares non-refundable, Flex fares refundable with fee
Pregnant on board
Pregnant women can fly up to 36 weeks (single pregnancy) or 32 weeks (multiple pregnancy). Medical certificate required after 28 weeks
Unaccompagned minor
Children aged 5-11 can travel unaccompanied with UM service. Service must be booked in advance and fees apply
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Wheelchair assistance available, must be requested 48h before flight
Pets
Small pets under 8kg allowed in cabin, larger animals in hold
Entertaiment on board
DELTA
About
Delta Air Lines is a leading U.S. carrier with an extensive global network, operating flights across the United States and to Europe, Asia, Latin America, and beyond. Whether flying economy, premium economy, or Delta One, passengers enjoy excellent service and onboard amenities such as WiFi, entertainment, dining options, and extra comfort depending on the route. With competitive fares and a reputation for high-quality service, Delta offers travelers an accessible and enjoyable way to reach their destination.
Luggage & cancellation policy
DELTA frequency
10 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item included in main cabin
Additional luggage
Checked bags fees vary by route, typically $30-$60 for first bag
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with possible fee, refunds depend on fare rules
Pregnant on board
Pregnant travelers can fly up to 4 weeks before due date without medical certificate. After 36 weeks, medical certificate required
Unaccompagned minor
Children ages 5-14 can travel alone using Delta's Unaccompanied Minor program. Service fee is $150 each way
Amenities on board the airplane
Wifi
USB plugs
Accessibility
Delta provides assistance for passengers with disabilities, including wheelchair services and special assistance during boarding and deplaning
Pets
Small dogs and cats allowed in cabin for fee of $125 each way on most flights
Entertaiment on board
FAQs: Santo Domingo to Madrid Flight
Find answers to the most common questions about traveling from Santo Domingo to Madrid by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

Cheap plane tickets from Santo Domingo to Madrid can start from as little as $292 (€237) when you book in advance. The average flight ticket price for Santo Domingo to Madrid is $787 (€639) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by plane from Santo Domingo to Madrid is 8h 5m to travel the 4163 miles (6700 km) long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest flight from Santo Domingo to Madrid leaves at 12:30 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Santo Domingo to Madrid leaves at 11:50 PM.
Yes, there are 3 direct flights a day from Santo Domingo to Madrid with Air Europa. Schedules can vary on holidays or weekends with fewer direct flights.
When taking a flight from Santo Domingo to Madrid, you can count on Iberia, Air Europa, World2Fly, American Airlines, DELTA for the best way to get you to Madrid. You can also check all possible airlines who offer a service between Santo Domingo and Madrid and compare the amenities they offer before buying a plane ticket.
Flights from Santo Domingo to Madrid generally leave from Santo Domingo and arrive in Madrid Barajas Airport.Santo Domingo is 3 miles (6 km) away from Santo Domingo city centre and Madrid Barajas Airport is 7 miles (12 km) from Madrid city centre.
The cheapest month for a flight from Santo Domingo to Madrid is April.
Yes, you can take a flight between Santo Domingo and Madrid.
Madrid is within the Schengen Area. Passport and visa requirements depend on your nationality. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is a time difference of 5 h in winter and 6 h in summer between Santo Domingo and Madrid.
The best events to attend in Madrid include:
- San Isidro Festival, a celebration honoring the patron saint of Madrid with parades and traditional music
- Madrid Pride, one of the largest LGBTQ+ pride events in Europe featuring a colorful parade
- La Paloma Festival, a local festival celebrating the Virgin of La Paloma with street parties and cultural activities
- Madrid Fashion Week, a showcase of the latest trends and designs from Spanish and international fashion designers.
The best holidays to experience in Madrid include:
- Epiphany, January, a traditional celebration with parades and the Three Kings' Day festivities
- Semana Santa, April, a significant religious observance with processions and cultural significance
- Assumption of Mary, August, a public holiday with various local celebrations and events
- National Day of Spain, October, commemorating the country's history with patriotic displays and activities.
The best season to visit Madrid is Spring or Fall. The best weather to explore Madrid is during April-June or September-October.
For international flights we recommend to arrive 2.5 to 3 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
popular airports
Popular airports from Santo Domingo to Madrid
Santo Domingo
Madrid
The major airport for departures in Santo Domingo is Santo Domingo. Find all the information you need to know about services, amenities and connections at Santo Domingo for your trip from Santo Domingo to Madrid.
Amenities at airport
information
Distance to city center
6 kmCar connection
Autopista Las Américas, Exit 22Wifi
- Free Wi-Fi available throughout the airport.
Shopping
- Various shops are available, including duty-free and souvenir shops.
Parking
- Parking available with options for short-term and long-term parking, approximately 1.9€ ($2) per hour.
Dining
- Several restaurants are available, including local cuisine and fast food options. Top choices include Café Santo Domingo and Pizza Hut.
Taxis
- Available outside the terminal.
WC
- Available throughout the airport.
Hotel
- Hotels are available within walking distance, including the Quality Hotel Real Aeropuerto Santo Domingo.
Shower
- Showers are available in some lounges; prices vary.
Lounge
- Lounges available, including the VIP Lounge.
Lost and Found Office
- Lost and Found located in the arrivals area.
Car Rental
- Car rental services are available from major providers like Hertz and Avis.
Public transit options for Santo Domingo
- Bus OMSA, Route 40B, 30 km
The major airport for arrivals in Madrid is Madrid Barajas Airport. Find all the information you need to know about services, amenities and connections at Madrid Barajas Airport for your journey to Madrid from Santo Domingo.
Amenities at airport
information
Distance to city center
12 kmCar connection
M-14, exit 2Wifi
- Free Wi-Fi available throughout the airport.
Shopping
- Shops in all terminals, including duty-free and fashion brands.
Parking
- Parking available at all terminals, approximately 2.5€ per hour.
Taxis
- Available outside the terminal.
Accessibility
- Ramps, assistance.
WC
- Available throughout the airport.
Shower
- Yes
Lounge
- Lounges available in all terminals, including VIP lounges.
Lost and Found Office
- Located in Terminal 1, 2, and 4.
Public transit options for Madrid Barajas Airport
- Metro: Line 8
- Bus: Lines 101, 200, Exprés-203
- Train: Cercanías C1, C10
More options for your journey from Santo Domingo to Madrid
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