- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Flights from Santander to Lyon depart on average 5 times per day, taking around 2h 45m. Cheap flight tickets for this journey start at €67 but you can travel from only €36 by bus.
The earliest flight runs at 00:10, the last at 23:40. The fastest flight covers the 453 miles (730 km) distance in 4h 15m. November is the cheapest month to fly.
Distance 453 miles (730 km) |
Average flight duration 2h 45m |
Cheapest ticket price €67 |
Flights per day 5 |
Fastest flight 4h 15m |
First flight 12:10 AM |
Last flight 11:40 PM |
Cheapest Month Nov |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Thu |
Least Busy Day Fri |
Best time to book 21 days |
Cheapest price
€105
Average price
€168
Fastest journey
9 h 47 m
Average duration
11 h 28 m
Flights per day
10
Distance
730 km
The best way to find a cheap flight ticket from Santander to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santander to Lyon will cost around €168 if you buy it on the day, but the cheapest tickets can be found for only €105.
It's difficult to get from Santander to Lyon without transferring at least once.
IB1066 · IB579+
9844
IB1066 · IB579+
5124
IB1066 · IB589+
9844
IB1060 · IB579+
9844
04072+
IB1185
04142+
IB1185
04072+
IB1183
IB1060 · IB579+
5124
IB1060 · IB579+
9844
IB1060 · IB589+
9844Omio recommends booking the bus as it is the most popular option from Santander to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €36. For those with little time consider booking a flight which can get you there in 2h 45m. The ticket price range depends on the travel mode: a bus costs an average of €36, and a flight costs an average of €67.
Distance: 453 miles (730 km)
| Flight | Most popular Bus | Train | Driving |
|---|---|---|---|
€217 Average price | €70 Average price Cheapest | €154 Average price | €158 Average price (fuel + tolls) |
5h 45m Average total duration Fastest 2h 45m Onboard + 3h 0m Additional time* | 15h 36m Average total duration 15h 6m Onboard + 30m Additional time* | 23h 52m Average total duration 23h 22m Onboard + 30m Additional time* | 9h 42m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santander to Lyon:
A bus is €84 less than a train for this route with tickets for a train from Santander to Lyon costing on average €154.
A bus is €147 less than a flight for this route with tickets for a flight from Santander to Lyon costing on average €217.
Other travel options to Lyon take longer:
Bus takes on average 15h 6m.
Train takes on average 23h 22m.
The table below shows live departures for Santander to Lyon flights for tomorrow, Wednesday, August 5. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
IB1066 · IB579+ 5124 | 6:30 AM Santander Airport | 15h29 | 9:59 PM Lyon Part Dieu | 2 transfers | |
IB1066 · IB579+ 9844 | 6:30 AM Santander Airport | 15h29 | 9:59 PM Lyon Part Dieu | 2 transfers | |
IB1066 · IB589+ 9844 | 6:30 AM Santander Airport | 15h29 | 9:59 PM Lyon Part Dieu | 2 transfers | |
04072+ IB1183 | On time 6:48 AM Santander station | 11h52 | 6:40 PM Lyon Saint Exupery Airport | 1 transfer | |
04072+ IB1185 | On time 6:48 AM Santander station | 16h57 | 11:45 PM Lyon Saint Exupery Airport | 1 transfer | |
04072+ SN3728+ SN3593 | On time 6:48 AM Santander station | 15h32 | 10:20 PM Lyon Saint Exupery Airport | 2 transfers | |
IB1060 · IB579+ 5124 | 10:05 AM Santander Airport | 11h54 | 9:59 PM Lyon Part Dieu | 2 transfers | |
IB1060 · IB579+ 9844 | 10:05 AM Santander Airport | 11h54 | 9:59 PM Lyon Part Dieu | 2 transfers | |
IB1060 · IB589+ 9844 | 10:05 AM Santander Airport | 11h54 | 9:59 PM Lyon Part Dieu | 2 transfers | |
04142+ IB1185 | 1:58 PM Santander station | 9h47 | 11:45 PM Lyon Saint Exupery Airport | 1 transfer | |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Santander to Lyon by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Santander to Lyon flights use the Santander Airport to Lyon Saint Exupery Airport airport pair. Use this guide to compare Santander and Lyon airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Santander Airport is 4 km from Santander city centre. Public transport options include:
Santander Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Lounge, and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in the terminal.
Lost and found is available at the station.
Available at Santander Airport: Parking, Taxis, WC.
Accessibility facilities are available at Santander Airport: Elevators, ramps.
Lyon Saint Exupery Airport is 2 km from Lyon city centre. Public transport options include:
Lyon Saint Exupery Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Shower, Lounge, and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in all terminals 1 and 2.
Lost and found is available at the station.
Available at Lyon Saint Exupery Airport: Parking, Taxis, WC.
Accessibility facilities are available at Lyon Saint Exupery Airport: Elevators, ramps.
Here are some other resources that might have the information you need