- Must visit
Royal Museums of Fine Arts of Belgium
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Flights from Santander to Brussels depart on average 8 times per day, taking around 3h 6m. Cheap flight tickets for this journey start at €19 if you book in advance.
There are 1 flights per day. The earliest flight runs at 05:53, the last at 22:15. The fastest flight covers the 637 miles (1026 km) distance in 1h 50m. February is the cheapest month to fly.
Distance 637 miles (1026 km) |
Average flight duration 3h 6m |
Cheapest ticket price €19 |
Flights per day 8 |
Direct flights 1 |
Fastest flight 1h 50m |
First flight 5:53 AM |
Last flight 10:15 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 42 days |
Cheapest price
€36
Average price
€259
Fastest journey
1 h 50 m
Average duration
4 h 35 m
Flights per day
15
Distance
1026 km
The best way to find a cheap flight ticket from Santander to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santander to Brussels will cost around €259 if you buy it on the day, but the cheapest tickets can be found for only €36.
Of the 15 flights that leave Santander for Brussels onWed, Aug 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct flights cover the 1026 km distance in an average of 4 h 35 m but if you time it right, some flights will get you there in just 1 h 50 m .
On Wed, Aug 05 the longest flights will take 5 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FR 6058
VY1597 · VY8984
IB1064 · IB603
VY1597 · VY8988
IB1060 · IB603
FR 6058
IB1064 · IB603
IB1066 · IB597
IB5353 · IB5290
VY1597 · VY8984Omio recommends booking the flight as it is the most popular option from Santander to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €62. For those with little time consider booking a flight which can get you there in 3h 6m. The ticket price range depends on the travel mode: a bus costs an average of €62, and a flight costs an average of €19.
Distance: 637 miles (1026 km)
Most popular Flight | Bus | Driving |
|---|---|---|
€127 Average price | €111 Average price Cheapest | €214 Average price (fuel + tolls) |
6h 6m Average total duration Fastest 3h 6m Onboard + 3h 0m Additional time* | 18h 37m Average total duration 18h 7m Onboard + 30m Additional time* | 13h 18m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santander to Brussels:
A bus is €16 less than a flight for this route with tickets for a flight from Santander to Brussels costing on average €127.
Other travel options to Brussels take longer:
Bus takes on average 18h 7m.
The table below shows live departures for Santander to Brussels flights for tomorrow, Wednesday, August 5. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
IB1066 · IB601 | 6:30 AM Santander Airport | 12h30 | 7:00 PM Brussels Airport | 1 transfer | |
IB1066 · IB1345+ 9398 | 6:30 AM Santander Airport | 16h36 | 11:06 PM Brussels-Midi | 2 transfers | |
IB1066 · IB597 | 6:30 AM Santander Airport | 4h55 | 11:25 AM Brussels Airport | 1 transfer | |
IB1066 · IB733+ 9398 | 6:30 AM Santander Airport | 16h36 | 11:06 PM Brussels-Midi | 2 transfers | |
IB1066 · IB1345+ 9364 | 6:30 AM Santander Airport | 10h36 | 5:06 PM Brussels-Midi | 2 transfers | |
IB1060 · IB603 | 10:05 AM Santander Airport | 12h25 | 10:30 PM Brussels Airport | 1 transfer | |
IB1060 · IB601 | 10:05 AM Santander Airport | 8h55 | 7:00 PM Brussels Airport | 1 transfer | |
IB1060 · IB733+ 9398 | 10:05 AM Santander Airport | 13h01 | 11:06 PM Brussels-Midi | 2 transfers | |
BA7056+ BA438+ 9398+ IB1060 | 10:05 AM Santander Airport | 13h01 | 11:06 PM Brussels-Midi | 3 transfers | |
VY1597 · VY8988 | 2:30 PM Santander Airport | 6h50 | 9:20 PM Brussels Airport | 1 transfer | |
IB5353 · IB5290 | 2:30 PM Santander Airport | 5h40 | 8:10 PM Brussels Airport | 1 transfer | |
IB5353 · IB5690 | 2:30 PM Santander Airport | 6h50 | 9:20 PM Brussels Airport | 1 transfer | |
VY1597 · VY8984 | 2:30 PM Santander Airport | 5h40 | 8:10 PM Brussels Airport | 1 transfer | |
FR 6058 | 3:25 PM Santander Airport | 1h50 | 5:15 PM Brussels South Charleroi Airport | 0 transfersDirect | |
IB1064 · IB603 | 5:40 PM Santander Airport | 4h50 | 10:30 PM Brussels Airport | 1 transfer | |
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Premier fine arts complex with Old Masters, Magritte, and modern collections, essential for understanding Belgian and European art.
Dedicated to surrealist René Magritte, this popular museum presents major works and context for one of Belgium’s most celebrated artists.
Leading comic art museum in a Horta-designed building, highlighting Tintin, the Smurfs, and Belgium’s influential comics culture.
Grand square at Brussels’ heart, lined with ornate guildhalls and lively events, perfect for first-time visitors and evening atmosphere.
Large urban park with the triumphal arch, museums, and wide lawns, excellent for walking, picnics, and classic city photographs.
Popular hilltop viewpoint and garden terrace with one of the best panoramas over central Brussels, especially at sunset.
Mussels steamed with white wine, celery and onion, often served with fries. A Brussels brasserie classic, especially popular in mussel season.
Double-fried potato fries, traditionally served in paper cones with sauces. They are a point of national pride and central to everyday Belgian street food.
A rich beef and onion stew braised with Belgian dark beer. It is a beloved comfort dish found in traditional Brussels restaurants.
Two-Michelin-star restaurant by chef Karen Torosyan, celebrated for pâté en croûte and inventive fine dining in an intimate setting.
Elegant Belle Époque brasserie serving refined Belgian classics, seafood and game in a grand old-world dining room.
Famous casual stop for Brussels waffles with many toppings. Popular, fast-moving and central for a classic sweet local treat.
Moderate for Western Europe: hotels can be pricey, but dining and transit are manageable for most tourists.
Service is usually included. Round up or leave 5-10% for great restaurant service; round up taxi fares; small change is fine in cafes.
Official public transport app
Brussels South Charleroi Airport -> Brussels Midi Station
Find answers to the most common questions about traveling from Santander to Brussels by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most Santander to Brussels flights use the Santander Airport to Brussels Airport airport pair, with some services landing at Brussels South Charleroi Airport. Use this guide to compare Santander and Brussels airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Santander Airport is 4 km from Santander city centre. Public transport options include:
Santander Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Lounge, and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in the terminal.
Lost and found is available at the station.
Available at Santander Airport: Parking, Taxis, WC.
Accessibility facilities are available at Santander Airport: Elevators, ramps.
Brussels Airport is 1 km from Brussels city centre. Public transport options include:
Brussels Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Shower, Lounge, and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in the departures and arrivals areas.
Lost and found is available at the station.
Available at Brussels Airport: Parking, Taxis, WC.
Accessibility facilities are available at Brussels Airport: Elevators, ramps, assistance.
Brussels South Charleroi Airport is 5 km from Brussels city centre. Public transport options include:
Brussels South Charleroi Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Shower, Lounge, and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in the terminal.
Lost and found is available at the station.
Available at Brussels South Charleroi Airport: Parking, Taxis, WC.
Accessibility facilities are available at Brussels South Charleroi Airport: Ramps, assistance.
Here are some other resources that might have the information you need