Journey information
Overview: Santander to Brussels flight
Flights from Santander to Brussels depart on average 8 times per day, taking around 3h 5m. Cheap flight tickets for this journey start at $21 (€17) if you book in advance.
There are 1 flights per day. The earliest flight runs at 05:53, the last at 22:25. The fastest flight covers the 637 miles (1026 km) distance in 1h 55m. July is the cheapest month to fly.
Distance 637 miles (1026 km) |
Average flight duration 3h 5m |
Cheapest ticket price $21 (€17) |
Flights per day 8 |
Direct flights 1 |
Fastest flight 1h 55m |
First flight 05:53 |
Last flight 22:25 |
Cheapest month Jul |
Cheapest day Sat |
High season Oct - Dec |
Low season Apr - Jun |
Busiest day Sat |
Least busy day Sun |
Best day to book ahead 42 days |
The cheapest and fastest flights from Santander to Brussels
Cheapest price
$401
Average price
$598
Fastest journey
4 h 55 m
Average duration
10 h 22 m
Flights per day
3
Distance
1026 km
The best way to find a cheap flight ticket from Santander to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santander to Brussels will cost around $598 if you buy it on the day, but the cheapest tickets can be found for only $401.
Of the 3 flights that leave Santander for Brussels onSun, Mar 22, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 22 the direct flights cover the 1026 km distance in an average of 10 h 22 m but if you time it right, some flights will get you there in just 4 h 55 m .
On Sun, Mar 22 the longest flights will take 13 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare bus and flight for Santander to Brussels
Omio recommends booking the flight as it is the most popular option from Santander to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $47. For those with little time consider booking a flight which can get you there in 3h 5m. The ticket price range depends on the travel mode: a bus costs an average of $47, and a flight costs an average of $21.
Distance: 637 miles (1026 km)
Compare flight with
Most popular Flight | Bus |
|---|---|
$172 Average price | $121 Average price Cheapest |
6h 5m Average total duration Fastest 3h 5m Onboard + 3h 0m Additional time* | 18h 37m Average total duration 18h 7m Onboard + 30m Additional time* |
![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Santander to Brussels flight times
The table below shows live departures for Santander to Brussels flights for today, Saturday, March 21. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:50 PM Santander | 1h55 | 9:45 PM Brussels | 0 transfersDirect | |
| Sunday, March 22 | |||||
![]() | 7:15 AM Santander | 13h00 | 8:15 PM Brussels | 0 transfersDirect | |
![]() | 8:25 AM Santander | 13h10 | 9:35 PM Brussels | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santander to Brussels by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
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Why should you book Santander to Brussels flights with Omio?
Why book with Omio vs Ryanair?
- Compare with other providers: On Omio, you can not only buy tickets for Ryanair, but also compare tickets for the likes of Vueling Airlines, Iberia or Air Nostrum to find the best option for your trip from Santander to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Ryanair with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Santander to Brussels.
Why book with Omio over Edreams, Kayak or Skyscanner?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Vueling Airlines, Iberia or Air Nostrum to find the best option for your trip from Santander to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Santander to Brussels.
Airlines: Ryanair, Vueling Airlines, Iberia, Air Nostrum from Santander to BrusselsFind the best flights between Santander to Brussels with Omio's travel partners Ryanair, Vueling Airlines, Iberia, Air Nostrum from $21 (€17). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Vueling Airlines
Iberia
Air Nostrum
Ryanair
FAQs: Santander to Brussels Flight
Find answers to the most common questions about traveling from Santander to Brussels by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

- Ommegang, a historical pageant celebrating the medieval heritage of Brussels
- Brussels Flower Carpet, a stunning floral display in the Grand Place every two years
- Brussels Jazz Marathon, a weekend of free jazz performances across the city
- Belgian Beer Weekend, a festival showcasing Belgium's rich beer culture with tastings and workshops.
- New Year's Day, a time for fresh beginnings and local celebrations
- Easter Monday, a public holiday with family gatherings and spring festivities
- Ascension Day, a day off for locals to enjoy the early summer weather
- National Day, celebrating Belgium's independence with parades and fireworks
- All Saints' Day, a day for remembrance and autumn reflections.
popular airports
Popular airports from Santander to Brussels
- Free Wi-Fi available throughout the airport.
- Shops available, including duty-free and convenience stores.
- Parking available near the terminal, approximately 1.2€ per hour.
- Available outside the terminal.
- Elevators, ramps.
- Available throughout the airport.
- Lounge available, access with membership or fee.
- Located in the terminal, contact information desk.
- Bus: ALSA, 17
- Train: RENFE
- Free Wi-Fi available throughout the airport.
- Shops located in Pier A and Pier B, includes Duty-Free and fashion stores.
- Parking available at P1, P2, and P3, approximately 4€ per hour.
- Available outside the terminal.
- Elevators, ramps, assistance.
- Available throughout the airport.
- Yes
- Lounges available in Pier A and Pier B, includes Brussels Airlines and Diamond Lounges.
- Located in the arrivals area.
- Bus: 272, 471
- Train: IC, S2, S4, S5, S9
- Free Wi-Fi available throughout the airport.
- Shops available, including duty-free and convenience stores.
- Parking available, P1 and P2 close to terminal, approximately 5€ per hour.
- Available outside the terminal.
- Ramps, assistance.
- Available throughout the airport.
- Yes
- Lounge available, The Lounge by Brussels South Charleroi Airport.
- Located in the terminal, near arrivals.
- Bus A
- Bus 68
- Bus 69
- Bus 80
Most popular flights from Santander
More options for your journey from Santander to Brussels
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