- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Flights from Santander to Rome depart on average 12 times per day, taking around 3h 24m. Cheap flight tickets for this journey start at $31 (€25) if you book in advance.
The earliest flight runs at 04:45, the last at 23:15. The fastest flight covers the 833 miles (1341 km) distance in 2h 15m. January is the cheapest month to fly.
Distance 833 miles (1341 km) |
Average flight duration 3h 24m |
Cheapest ticket price $31 (€25) |
Flights per day 12 |
Fastest flight 2h 15m |
First flight 4:45 AM |
Last flight 11:15 PM |
Cheapest Month Jan |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 49 days |
Cheapest price on Sep 11
$93
Average ticket price on Sep 11
$329
Fastest journey on Sep 11
4 h 40 m
Average journey duration on Sep 11
6 h 36 m
Flights on Sep 11
21
Distance
1341 km
The best way to find a cheap flight ticket from Santander to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santander to Rome will cost around $329 if you buy it on the day, but the cheapest tickets can be found for only $93.
It's difficult to get from Santander to Rome without transferring at least once.
04142+
W46016
04072+
W46014
04142+
W46016
04142+
IB657
04072+
W46014
IB1066 · IB647
IB1066 · IB659
IB1064 · IB657
IB1066 · IB649
IB1060 · IB653Omio recommends booking the flight as it is the most popular option from Santander to Rome among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $240 For those with little time, consider booking a flight, which has an average total journey time of 5h 24m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 1.3 - 3.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $240, while a flight costs an average of $305.
Distance: 833 miles (1341 km)
Most popular Flight | Bus | Driving |
|---|---|---|
$305 Average price | $240 Average price Cheapest | $367 Average price (fuel + tolls) |
5h 24m Average total duration Fastest 3h 24m Onboard + 2h 0m Additional time* | 33h 32m Average total duration 33h 2m Onboard + 30m Additional time* | 17h 58m Average total duration (door-to-door) |
4.0 - 8.0kg CO2 emissions | 1.3 - 3.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Santander to Rome:
A bus is $65 (€53) less than a flight for this route with tickets for a flight from Santander to Rome costing on average $305 (€247).
Other travel options to Rome take longer:
Bus takes on average 33h 2m.
The table below shows live departures for Santander to Rome flights for today, Thursday, September 10. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:40 PM Santander | 6h35 | 11:15 PM Rome | 0 transfersDirect | |
| Friday, September 11 | |||||
IB1066 · IB655 | 6:30 AM Santander Airport | 13h10 | 7:40 PM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
IB1066 · IB659 | 6:30 AM Santander Airport | 6h10 | 12:40 PM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
IB1066 · IB653 | 6:30 AM Santander Airport | 11h45 | 6:15 PM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
IB1066 · IB647 | 6:30 AM Santander Airport | 4h40 | 11:10 AM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
IB1066 · IB649 | 6:30 AM Santander Airport | 7h25 | 1:55 PM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
04072+ UX1047 | 6:48 AM Santander station | 10h37 | 5:25 PM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
04072+ IB657 | 6:48 AM Santander station | 17h27 | 12:15 AM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
04072+ W46014 | 6:48 AM Santander station | 16h17 | 11:05 PM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
04072+ AZ63 | 7:05 AM Santander station | 13h25 | 8:30 PM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
04072+ IB653 | 7:05 AM Santander station | 11h10 | 6:15 PM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
04072+ W46014 | 7:05 AM Santander station | 16h00 | 11:05 PM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
IB1060 · IB655 | 10:05 AM Santander Airport | 9h35 | 7:40 PM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
IB1060 · IB653 | 10:05 AM Santander Airport | 8h10 | 6:15 PM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
04142+ IB657 | 1:55 PM Santander station | 10h20 | 12:15 AM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
04142+ W46016 | 1:55 PM Santander station | 11h30 | 1:25 AM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
04142+ TP1021 · TP830 | 1:55 PM Santander station | 20h25 | 10:20 AM Rome Leonardo da Vinci Fiumicino Airport | 2 transfers | |
04142+ IB657 | 1:58 PM Santander station | 10h17 | 12:15 AM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
04142+ W46016 | 1:58 PM Santander station | 11h27 | 1:25 AM Rome Leonardo da Vinci Fiumicino Airport | 1 transfer | |
04142+ TP832 · TP1021 | 1:58 PM Santander station | 22h37 | 12:35 PM Rome Leonardo da Vinci Fiumicino Airport | 2 transfers | |
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Fiumicino Aeroporto -> Roma Termini
Find answers to the most common questions about traveling from Santander to Rome by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Santander to Rome flights use the Santander Airport to Rome Leonardo da Vinci Fiumicino Airport airport pair. Use this guide to compare Santander and Rome airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Santander Airport is 4 km from Santander city centre. Public transport options include:
Santander Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Lounge, and Lost and Found Office.
Free Wi-Fi available throughout the airport. ATMs are located in the terminal.
Lost and found is available at the station.
Available at Santander Airport: Parking, Taxis, WC.
Accessibility facilities are available at Santander Airport: Elevators, ramps.
Rome Leonardo da Vinci Fiumicino Airport is 3 km from Rome city centre. Public transport options include:
Rome Leonardo da Vinci Fiumicino Airport has practical services for this route, including Wifi, Shopping, Parking, ATM, Taxis, Accessibility, WC, Shower, Lounge, and Lost and Found Office.
Free Wi-Fi available throughout the airport for an unlimited duration. ATMs are located throughout the airport in all terminals.
Lost and found is available at the station.
Available at Rome Leonardo da Vinci Fiumicino Airport: Parking, Taxis, WC.
Accessibility facilities are available at Rome Leonardo da Vinci Fiumicino Airport: Ramps, assistance, toilets.
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