- Recommended
Greenville County Museum of Art
A major art museum in downtown Greenville with American art, Southern works, and rotating exhibitions in a bright riverfront setting.
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The cheapest and fastest flights from Jacksonville, FL to Greenville, SC
Showing times, prices and bookable tickets for Nov 07
- Cheapest price on Nov 07
- $216
- Average ticket price on Nov 07
- $254
- Fastest journey on Nov 07
- 3 h 38 m
- Average journey duration on Nov 07
- 3 h 39 m
- Flights on Nov 07
- 2
- Distance
- 507 km
Cheap tickets
The best way to find a cheap flight ticket from Jacksonville, FL to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Jacksonville, FL to Greenville, SC will cost around $254 if you buy it on the day, but the cheapest tickets can be found for only $216.
Fast flights
On Sat, Nov 07, we found 2 flights from Jacksonville, FL to Greenville, SC, including 2 direct services.
On Sat, Nov 07 the direct flights cover the 507 km distance in an average of 3 h 39 m but if you time it right, some flights will get you there in just 3 h 38 m .
On Sat, Nov 07 the longest flights will take 3 h 39 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12:19 AM 3h38 Jacksonville, FL 3:57 AM Greenville, SC $216 1 One-way 0 transfers11:09 PM 3h39 Jacksonville, FL 2:48 AM Greenville, SC $293 1 One-way 0 transfers
12:19 AM 3h38 Jacksonville, FL 3:57 AM Greenville, SC $216 1 One-way 0 transfers11:09 PM 3h39 Jacksonville, FL 2:48 AM Greenville, SC $293 1 One-way 0 transfers
Journey information
Overview: Jacksonville, FL to Greenville, SC flight
USAUSA
Flights from Jacksonville, FL to Greenville, SC depart on average 22 times per day, taking around 3h 26m. Cheap flight tickets for this journey start at $117 (€98) but you can travel from only $59 (€49) by bus.
The earliest flight runs at 05:00, the last at 20:37. The fastest flight covers the 315 miles (507 km) distance in 2h 13m. November is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $59 (€49)
Plan this route
Journey facts
- Distance315 miles (507 km)
- Average flight duration3h 26m
- Cheapest ticket price$117 (€98)
- Flights per day22
- Fastest flight2h 13m
- First flight5:00 AM
- Last flight8:37 PM
- Cheapest MonthNov
- Cheapest DaySat
- High SeasonJul - Sep
- Low SeasonOct - Dec
Understand & plan this route
- Operators on this routeAmerican Airlines • psa airlines • Republic Airlines
- Departure & arrivalJacksonville International Airport → Greenville-Spartanburg International Airport
- Airport shuttle busesTo Jacksonville International Airport
- Arrival airportGreenville-Spartanburg International Airport
- Flights with a stopAvailable on this route
Explore this journey
Book with confidence
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $59 (€49)
Frequently asked questions about your Jacksonville, FL to Greenville, SC trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Jacksonville, FL to Greenville, SC.
Cheap plane tickets from Jacksonville, FL to Greenville, SC can start from as little as $117 (€98) when you book in advance. The average flight ticket price for Jacksonville, FL to Greenville, SC is $637 (€534) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest flight from Jacksonville, FL to Greenville, SC leaves at 5:00 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from Jacksonville, FL to Greenville, SC leaves at 8:37 PM.
There are {frequency} flights a day from Jacksonville, FL to Greenville, SC which require at least one change with {providers}. Schedules can vary on holidays or weekends with fewer flights.
Live departures
Jacksonville, FL to Greenville, SC flight times
The table below shows live departures for Jacksonville, FL to Greenville, SC flights for today, Saturday, October 31. You can also manually refresh the results below to see updated flight journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 6:22 PM Jacksonville, FL | 4h33 | 10:55 PM Greenville, SC | 0 transfersDirect | |
| Sunday, November 1 | |||||
| 12:19 AM Jacksonville, FL | 3h38 | 3:57 AM Greenville, SC | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Why should you book Jacksonville, FL to Greenville, SC flights with Omio?
American Airlines as well as psa airlines, Republic Airlines, piedmont airlines and more offer flights services from Jacksonville, FL to Greenville, SC.
Omio is an official ticket reseller for all your travel options from Jacksonville, FL to Greenville, SC.
Why book with Omio vs American Airlines?
- Compare with other providers: On Omio, you can not only buy tickets for American Airlines, but also compare tickets for the likes of psa airlines, Republic Airlines or piedmont airlines to find the best option for your trip from Jacksonville, FL to Greenville, SC.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare American Airlines with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Jacksonville, FL to Greenville, SC.
Why book with Omio over Trip, Edreams or Skyscanner?
- Compare with other providers: On Omio, you can also compare tickets for the likes of psa airlines, Republic Airlines or piedmont airlines to find the best option for your trip from Jacksonville, FL to Greenville, SC.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Jacksonville, FL to Greenville, SC.
Airlines
Airlines from Jacksonville, FL to Greenville, SC
Flights from Jacksonville, FL to Greenville, SC with American Airlines, psa airlines, and Republic Airlines. Flights with a stop available on this route with American Airlines, psa airlines, and Republic Airlines. Use the details below to compare onboard facilities.
American Airlines
About
American Airlines is one of the largest airlines in the world, connecting travelers to hundreds of destinations across the United States, Latin America, Europe, Asia, and beyond. Operating from major hubs such as Dallas/Fort Worth, Miami, and Charlotte, American offers a wide range of travel options. Passengers can choose from Economy with affordable fares, Premium Economy with extra space, or Business and First Class featuring flat-bed seats, premium dining, and lounge access. With a modern fleet and membership in the oneworld alliance, American Airlines combines global reach with comfort and reliability.
Luggage & cancellation policy
Average American Airlines Duration
2h 13m
Cheapest American Airlines Price
$117 (€98)
American Airlines frequency
18 a day
Luggage included
1 carry-on bag (22 x 14 x 9 inches) and 1 personal item (18 x 14 x 8 inches) included in most fares
Additional luggage
Checked bags fees vary by route. First checked bag typically $30, second $40 on domestic flights
Cancellation Policy
Basic Economy tickets cannot be changed or refunded. Other fares allow changes with fee, refunds subject to fare rules.
Pregnant on board
Passengers can fly up to 36 weeks for single pregnancies, 32 weeks for multiple pregnancies. Medical certificate required within 7 days of departure if within 4 weeks of due date.
Unaccompagned minor
Children ages 5-14 can travel alone using American Airlines Unaccompanied Minor Service. Service fee is $150 each way.
Amenities on board the airplane
Wifi
Food sold onboard
USB plugs
Accessibility
American Airlines provides wheelchair assistance and special services for passengers with disabilities. Assistance must be requested at least 48 hours before departure.
Pets
Small dogs and cats allowed in cabin for $125 fee. Must be in approved carrier under seat. Service animals allowed.
Entertaiment on board
piedmont airlines
About
Piedmont Airlines is an American regional airline and a wholly-owned subsidiary of the American Airlines Group. Headquartered in Salisbury, Maryland, Piedmont operates American Eagle flights, staffing, operating, and maintaining aircraft for American Airlines.The airline traces its roots back to Henson Aviation, founded in 1931, and was rebranded as Piedmont Airlines in 1993. Today, Piedmont operates a fleet of Embraer ERJ 145 regional jets, with nearly 400 daily departures to over 50 destinations, primarily throughout the eastern United States. Its main hubs include Philadelphia International Airport and Charlotte Douglas International Airport. Piedmont also provides ground handling and customer service for airports in the northeastern and western United States.
Luggage & cancellation policy
Average piedmont airlines Duration
5h 14m
Cheapest piedmont airlines Price
$576 (€483)
piedmont airlines frequency
1 a day
Luggage included
Piedmont Airlines, operating as American Eagle, follows American Airlines' baggage policy, which generally does not include free checked bags in Main Cabin fares. Passengers are allowed one carry-on bag and one personal item. The carry-on bag should not exceed 56 x 36 x 23 cm with a maximum weight of 10 kilograms, and the personal item should not exceed 45 x 35 x 20 cm.
Additional luggage
Additional luggage can be checked for a fee.
Cancellation Policy
If your flight is canceled or significantly changed, you are generally entitled to a refund if you decline alternative transportation or travel credits.
Refund
If your flight is canceled or significantly changed, you are generally entitled to a cash refund for your airfare and ancillary service fees if you decline any alternative transportation or travel credits offered by the airline.
Amenities on board the airplane
Food sold onboard
Complimentary non-alcoholic beverages are offered, and snacks and meals may be complimentary or available for purchase depending on the length and location of the flight.
USB plugs
Accessibility
Piedmont Airlines is committed to ensuring digital accessibility for people with disabilities and their website is fully conformant with WCAG 2.1 level AA. For in-flight or curbside assistance, including wheelchairs and help with luggage, passengers should contact the airline directly.
Pets
Small dogs and cats can accompany passengers in the cabin, provided they meet size and weight requirements. Pets are not allowed to travel in-cabin on international flights or any itinerary that includes an international flight.
psa airlines
About
PSA Airlines is an American regional airline and a wholly-owned subsidiary of the American Airlines Group, operating exclusively on behalf of American Airlines under the American Eagle brand. Headquartered in Charlotte, North Carolina, PSA Airlines operates over 800 daily flights to nearly 100 destinations across the United States. The airline maintains an all-jet fleet consisting of Bombardier CRJ700 and CRJ900 regional aircraft. With a team of over 5,000 employees, PSA Airlines plays a significant role in connecting smaller cities to major hubs within American Airlines' network.
Luggage & cancellation policy
Average psa airlines Duration
2h 38m
Cheapest psa airlines Price
$424 (€356)
psa airlines frequency
3 a day
Luggage included
One carry-on bag and one personal item are allowed.
Additional luggage
Additional luggage can be checked for a fee, with weight limits up to 32kg (70lbs) for a single piece.
Cancellation Policy
PSA Airlines' cancellation policy depends on the timeframe of cancellation and ticket flexibility, with some flexible ticket options offering easier cancellations.
Refund
Passengers are entitled to a refund if the airline cancels a flight and they choose not to travel.
Amenities on board the airplane
Food sold onboard
Non-alcoholic beverages are complimentary in Economy Class, while alcoholic drinks and snack boxes can be purchased.
Accessibility
Wheelchair assistance is available and should be requested at least 24 hours prior to flight departure.
Republic Airlines
About
Republic Airways is a major regional airline in the United States, operating as a subsidiary of Republic Airways Holdings. It provides scheduled passenger service for American Airlines (as American Eagle), Delta Air Lines (as Delta Connection), and United Airlines (as United Express) using a fleet of Embraer 170 and 175 regional jets. Headquartered in Indianapolis, Indiana, Republic Airways operates over 900 daily flights to more than 80 cities across the U.S. and Canada. The company is known for its large fleet of Embraer E-Jets and its state-of-the-art training facilities. In April 2025, Republic Airways Holdings announced its acquisition of Mesa Air Group, which is expected to create the second-largest regional carrier in the U.S.
Luggage & cancellation policy
Average Republic Airlines Duration
3h 26m
Cheapest Republic Airlines Price
$285 (€239)
Republic Airlines frequency
2 a day
Luggage included
One carry-on bag (24 x 16 x 10) and one personal item
Additional luggage
Checked bags for a fee
Cancellation Policy
Tickets are non-refundable but may be cancelled for future flight credit minus applicable fees
Pregnant on board
Passengers can fly up to the end of their 36th week for single pregnancies and the end of their 32nd week for multiple pregnancies
Unaccompagned minor
Unaccompanied minor service is available for children ages 5-14. Must be booked directly with Republic Airlines
Amenities on board the airplane
USB plugs
Accessibility
Republic Airlines offers assistance for passengers with reduced mobility, including wheelchair services and priority boarding. Passengers are advised to request these services in advance to ensure availability and proper arrangements.
Companies, tickets, and onboard amenities between Jacksonville, FL and Greenville, SC
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a flight from Jacksonville, FL to Greenville, SC, you can count on American Airlines, psa airlines, Republic Airlines, piedmont airlines for the best way to get you to Greenville, SC. You can also check all possible airlines who offer a service between Jacksonville, FL and Greenville, SC and compare the amenities they offer before buying a plane ticket.
For international flights we recommend to arrive 2.5 to 3 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
Complete guide to Greenville, SC
Things to do in Greenville, SC
Discover the best of Greenville, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Greenville, SC trip today.
Greenville Center for Creative Arts
A contemporary art center showing regional and international artists through rotating exhibitions in a modern downtown gallery space.
Metropolitan Arts Council Gallery
A local gallery and arts space featuring exhibitions, classes, and community-focused programming in Greenville's Village area.
- Must visit
Falls Park on the Reedy
A signature downtown park with waterfalls, gardens, river trails, and lawns. It is Greenville's most popular public space for walking and views.
- Must visit
Main Street
Greenville's central street lined with shops, public art, and historic buildings. It is ideal for strolling between downtown attractions.
- Recommended
Prisma Health Swamp Rabbit Trail
A swamp rabbit-themed riverside greenway popular for walking and cycling, linking downtown Greenville with parks and nearby districts.
- Gluten-free
South Carolina Mustard-Style Barbecue
South Carolina barbecue is slow-smoked pork, often chopped or pulled, and classically served with the state’s distinctive mustard-based sauce.
- Gluten-free
Shrimp And Grits
Shrimp and grits pairs creamy stone-ground grits with shrimp, often enriched with bacon or sausage. It is a Lowcountry staple found across Greenville.
- Vegetarian
Fried Green Tomatoes
Fried green tomatoes are tart unripe tomatoes breaded and fried. They are a beloved Southern side and common on Upstate menus.
Henry's Smokehouse
Casual Greenville barbecue spot serving smoked meats, classic sides, and a relaxed neighborhood atmosphere.
Hall's Chophouse Greenville
Upscale downtown steakhouse and oyster bar with dry-aged beef, seafood, and an elegant supper-club feel.
Soby's
Refined Southern restaurant known for seasonal plates, thoughtful cocktails, and a polished downtown setting.
United States dollar ($)
Moderate for a U.S. city. Hotels and dining are usually cheaper than major metros, but car travel and limited transit can add to visitor costs.
Average meal costs
- Budget
- $10-15 for fast food or a casual meal.
- Mid-range
- $20-35 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $3-5 for coffee or a cappuccino.
Tipping culture
Tip 18-20% at restaurants, more for excellent service. Taxis usually get 10-15%. Cafes often have tip jars; $1-2 is common for drinks.
Plan your visit to Greenville, SC
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Greenville, SC.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Greenville, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like downtown and popular events. Common scams include overcharging by unofficial taxi or ride-share drivers and fake charity solicitations. It is advisable to use authorized transportation services, avoid displaying valuables openly, and stay aware of surroundings, particularly at night.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Jacksonville, FL to Greenville, SC Flight
Find answers to the most common questions about traveling from Jacksonville, FL to Greenville, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 3 ways to travel between Jacksonville, FL and Greenville, SC including taking a bus, train, and flight.
popular airports
Popular airports from Jacksonville, FL to Greenville, SC
Most Jacksonville, FL to Greenville, SC flights use the Jacksonville International Airport to Greenville-Spartanburg International Airport airport pair. Use this guide to compare Jacksonville, FL and Greenville, SC airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
Departure airports in Jacksonville
Arrival airports in Greenville
Which Jacksonville, FL airport do flights to Greenville, SC leave from?
Flights from Jacksonville, FL to Greenville, SC depart from Jacksonville International Airport. The airport is 7 miles (12 km) from Jacksonville, FL city centre at 2400 Yankee Clipper Dr, Jacksonville, FL 32218, USA.
Jacksonville International Airport (JAX)2400 Yankee Clipper Dr, Jacksonville, FL 32218, USA
City-centre transport
Getting to Jacksonville International Airport from Jacksonville city centre
Jacksonville International Airport is 11 km from Jacksonville city centre. Public transport options include:
Bus1 · 53m · $4 · every ~3 min
1 · 56m · $4 · every ~3 min
Jacksonville International Airport airport facilities and services
Jacksonville International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food and drink
Food options include: Restaurants available in Concourse A and C, including fast food and sit-down options like Chili's and Vino Volo.
Wi-Fi and ATMs
Free Wi-Fi available throughout the airport. ATMs are located near baggage claim and ticketingas.
Luggage and lost property
Lost and found is available at the station.
Parking, taxis and toilets
Available at Jacksonville International Airport: Parking, Taxis, WC.
Bike and car services
Available at Jacksonville International Airport: Car Rental.
Accessibility
Accessibility facilities are available at Jacksonville International Airport: Elevators, toilets.
Shops, hotels and contact
Nearby hotels include Hotels nearby, such as DoubleTree by Hilton, within walking distance..
Which Greenville, SC airport do flights from Jacksonville, FL arrive at?
Flights from Jacksonville, FL to Greenville, SC arrive at Greenville-Spartanburg International Airport. Greenville-Spartanburg International Airport is 3 miles (5 km) from Greenville, SC city centre.
Greenville-Spartanburg International Airport (GSP)Greenville-Spartanburg International Airport (GSP), 2000 GSP Dr, Greer, SC 29651, USA
City-centre transport
Getting to Greenville-Spartanburg International Airport from Greenville city centre
Greenville-Spartanburg International Airport is 5 km from Greenville city centre. Public transport options include:
TRUE
Greenville-Spartanburg International Airport airport facilities and services
Greenville-Spartanburg International Airport has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options are available in the terminal.
Wi-Fi and ATMs
Free Wi-Fi available throughout the terminal. ATMs are aTMs available near baggage claim.
Tickets and information
Ticket office support is available at Greenville-Spartanburg International Airport.
Parking, taxis and toilets
Available at Greenville-Spartanburg International Airport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Greenville-Spartanburg International Airport: Elevators and ramps available for accessibility.
Airports for flights from Jacksonville, FL to Greenville, SC
See which airports are used for flights between Jacksonville, FL and Greenville, SC, including airport details.
Flights from Jacksonville, FL to Greenville, SC generally leave from Jacksonville International Airport and arrive in Greenville-Spartanburg International Airport.Jacksonville International Airport is 7 miles (12 km) away from Jacksonville, FL city centre and Greenville-Spartanburg International Airport is 3 miles (5 km) from Greenville, SC city centre.
Most popular flights to and from Greenville, SC and Jacksonville, FL
Most popular flights to Greenville, SC
HomeFlightsFlights in USAFlight Schedules to Greenville, SCJacksonville, FL to Greenville, SC Flights
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