Journey information
Overview: Jacksonville, FL to Greenville, SC flight
Flights from Jacksonville, FL to Greenville, SC depart on average 16 times per day, taking around 4h 31m. Cheap flight tickets for this journey start at $138 (€112) but you can travel from only $74 (€60) by bus.
The earliest flight runs at 05:00, the last at 20:37. The fastest flight covers the 315 miles (507 km) distance in 3h 39m. June is the cheapest month to fly.
Distance 315 miles (507 km) |
Average flight duration 4h 31m |
Cheapest ticket price $138 (€112) |
Flights per day 16 |
Fastest flight 3h 39m |
Cheapest month June |
First flight 05:00 |
Last flight 20:37 |
The cheapest and fastest flights from Jacksonville, FL to Greenville, SC
Cheapest price
$183
Average price
$243
Fastest journey
3 h 39 m
Average duration
4 h 53 m
Flights per day
2
Distance
507 km
The best way to find a cheap flight ticket from Jacksonville, FL to Greenville, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Jacksonville, FL to Greenville, SC will cost around $243 if you buy it on the day, but the cheapest tickets can be found for only $183.
Of the 2 flights that leave Jacksonville, FL for Greenville, SC onSun, Mar 08, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 08 the direct flights cover the 507 km distance in an average of 4 h 53 m but if you time it right, some flights will get you there in just 3 h 39 m .
On Sun, Mar 08 the longest flights will take 6 h 6 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Jacksonville, FL to Greenville, SC
Omio recommends booking the bus as it is the most popular option from Jacksonville, FL to Greenville, SC among Omio's users. If you are prioritising price take the bus with prices starting from $74. For those with little time consider booking a flight which can get you there in 4h 31m. The ticket price range depends on the travel mode: a bus costs an average of $74, and a flight costs an average of $138.
Distance: 315 miles (507 km)
Compare flight with
| Flight | Most popular Bus | Train |
|---|---|---|
$272 Average price | $128 Average price Cheapest | $208 Average price |
7h 31m Average total duration Fastest 4h 31m Onboard + 3h 0m Additional time* | 10h 30m Average total duration 10h 0m Onboard + 30m Additional time* | 25h 38m Average total duration 25h 8m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Jacksonville, FL to Greenville, SC flight times
The table below shows live departures for Jacksonville, FL to Greenville, SC flights for today, Saturday, March 7. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:22 PM Jacksonville, FL | 4h33 | 10:55 PM Greenville, SC | 0 transfersDirect | |
![]() | 9:57 PM Jacksonville, FL | 7h00 | 4:57 AM Greenville, SC | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Jacksonville, FL to Greenville, SC by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 08
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Mar 14
FAQs: Jacksonville, FL to Greenville, SC Flight
Find answers to the most common questions about traveling from Jacksonville, FL to Greenville, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Greenville, SC, this guide helps you travel smarter and with confidence.

- Greenville Jazz Festival, a vibrant celebration of jazz music featuring local and national artists performing in various venues
- Artisphere, an annual arts festival showcasing visual arts, live performances, and culinary delights from regional artists
- Fall for Greenville, a food and music festival highlighting the best local cuisine and entertainment in a family-friendly atmosphere.
- Memorial Day, the unofficial start of summer with vibrant local events and parades
- Independence Day, spectacular fireworks and festive celebrations throughout the city
- Labor Day, a perfect time for outdoor activities and community gatherings as summer winds down.
popular airports
Popular airports from Jacksonville, FL to Greenville, SC
- Free Wi-Fi available throughout the airport.
- Shops available in the main terminal, including newsstands and gift shops.
- Parking available near the terminal, approximately 1.1€ (20 MXN) per hour.
- Restaurants available in Concourse A and C, including fast food and sit-down options like Chili's and Vino Volo.
- Available outside the terminal.
- Elevators, toilets
- Available throughout the airport, near gates and baggage claim.
- Hotels nearby, such as DoubleTree by Hilton, within walking distance.
- Showers available in some lounges, check access requirements.
- Lounges available, including Delta Sky Club, with access for eligible passengers.
- Lost and Found located in the main terminal, near baggage claim.
- Car rental services available on-site, with major companies like Hertz and Avis.
- Bus Route 1, JTA stop at Airport terminal, 13 miles
More options for your journey from Jacksonville, FL to Greenville, SC
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